AmiGO 2: Term Details for "nucleolus" (GO:0005730)
️Gene Ontology Consortium
️Tue Nov 05 2024
Accession
GO:0005730
Name
nucleolus
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
Source:ISBN:0198506732