\documentclass[border=5mm]{standalone}
\usepackage{pgfplots}
\usepackage[super]{nth}
\usepackage{amsmath}
\pgfplotstableread{
Siglos Manuscritos Libros impresos
6 13552 nan
7 10639 nan
8 43702 nan
9 201742 nan
10 135637 nan
11 212030 nan
12 768721 nan
13 1761951 nan
14 2746951 nan
%15 4999161 12589000
16 nan 217444000
17 nan 531941000
18 nan 983874000
}\datatable
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\definecolor{RYB2}{RGB}{253, 180, 98}
\begin{document}
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axis lines*=left,
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yticklabels={1000, 10\,000, 100\,000, 1\,000\,000, 10\,000\,000, 100\,000\,000, 1\,000\,000\,000},
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ybar=-10pt, xtick={6,...,18}, xticklabel={\pgfmathparse{int(\tick)}\nth{\pgfmathresult}},
xlabel=Siglos, xlabel style={yshift=-1ex},ylabel=Número\\ de Copias,
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after end axis/.code={
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font=\large\bfseries,
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fill=white, fill opacity=0.85, text opacity=1,
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},
title={Producción Europea occidental de libros entre los años 500 y 1800$^{\text{\tiny{*}}}$},
title style={font=\large\bfseries, align=center}
]
\addplot +[fill=RYB1, draw=RYB1!50!black] table [y=Books] {\datatable};
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\node (annotation) at (current axis.below south west) [inner xsep=0pt, anchor=north west, align=left, font=\tiny] {$^*$without Southeast Europe (Byzantine, later Ottoman realm) and Russia};
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\end{document}