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Rpl4 MGI Mouse Gene Detail - MGI:1915141 - ribosomal protein L4

Summary

Symbol

Rpl4
Name

ribosomal protein L4
Synonyms

2010004J23Rik

Feature Type

protein coding gene
IDs

MGI:1915141
NCBI Gene: 67891
Alliance
Transcription Start Sites

2 TSS

Location &
Maps

Sequence Map

Chr9:64080657-64085948 bp, + strand
From Ensembl annotation of GRCm39
Genome Browsers

Genetic Map

Chromosome 9, 34.54 cM, cytoband D
Mapping Data

2 experiments

Strain
Comparison

SNPs within 2kb

199 from dbSNP Build 142
Strain Annotations

18

Homology

Human Ortholog

RPL4, ribosomal protein L4

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPL4, ribosomal protein L4
Synonyms

L4, uL4
Links
Chr Location

15q22.31; chr15:66498015-66524532 (-) GRCh38

MGI Vertebrate Homology
HCOP

vertebrate homology predictions: RPL4
Gene Tree

Mutations,
Alleles, and
Phenotypes

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Phenotype Summary

5 phenotype references

All Mutations and Alleles
Chemically induced (other)
Gene trapped
Targeted
Genomic Mutations

1 involving Rpl4
Incidental Mutations
Find Mice (IMSR)

Gene Ontology
(GO)
Classifications

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All GO Annotations
GO References

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

Expression

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Expression Overview

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results
Tissues
cDNA Data
Literature Summary

Other Mouse Links
Other Vertebrate Links

Sequences &
Gene Models

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All Sequences
RefSeq
UniProt
CCDS

Ensembl
NCBI Gene

Protein
Information

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UniProt

4 Sequences
Protein Ontology

PR:000014228 eukaryotic-type large ribosomal subunit protein uL4
PDB
InterPro Domains

IPR002136 Large ribosomal subunit protein uL4

IPR025755 Large ribosomal subunit protein uL4, C-terminal domain

IPR023574 Large ribosomal subunit protein uL4 domain superfamily

IPR045240 Large ribosomal subunit protein uL4, eukaryotic and archaeal type

IPR013000 Large ribosomal subunit protein uL4, eukaryotic/archaeal, conserved site
GlyGen

Q9D8E6 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)

Molecular
Reagents

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Primer pair 2

Microarray probesets 2

References

Summaries

Developmental Gene Expression 2

Gene Ontology 9

Phenotypes 5
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731