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Wdr76 MGI Mouse Gene Detail - MGI:1926186 - WD repeat domain 76

Summary

Symbol

Wdr76
Name

WD repeat domain 76
Synonyms

5830411K18Rik

Feature Type

protein coding gene
IDs

MGI:1926186
NCBI Gene: 241627
Alliance
Transcription Start Sites

6 TSS

Location &
Maps

Sequence Map

Chr2:121337204-121375341 bp, + strand
From NCBI annotation of GRCm39
Genome Browsers

Genetic Map

Chromosome 2, 60.41 cM, cytoband F1
Mapping Data

3 experiments

Strain
Comparison

SNPs within 2kb

979 from dbSNP Build 142
Strain Annotations

17

Homology

Human Ortholog

WDR76, WD repeat domain 76

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

WDR76, WD repeat domain 76
Synonyms

CDW14, CMR1
Links
Chr Location

15q15.3; chr15:43826980-43868412 (+) GRCh38

MGI Vertebrate Homology
HCOP

vertebrate homology predictions: WDR76
Gene Tree

Mutations,
Alleles, and
Phenotypes

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
11 phenotype references

All Mutations and Alleles
Chemically induced (other)
Endonuclease-mediated
Gene trapped
Radiation induced
Targeted
Genomic Mutations

2 involving Wdr76
Incidental Mutations
Find Mice (IMSR)

Mice homozygous for a knock-out allele are viable and fertile with no apparent developmental abnormalities.

Gene Ontology
(GO)
Classifications

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All GO Annotations
GO References

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

Expression

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Expression Overview

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results
cDNA Data

Other Mouse Links
Other Vertebrate Links

Sequences &
Gene Models

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All Sequences
RefSeq
UniProt
CCDS

Ensembl
NCBI Gene

Protein
Information

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UniProt

2 Sequences
Protein Ontology
InterPro Domains

IPR036322 WD40-repeat-containing domain superfamily

IPR015943 WD40/YVTN repeat-like-containing domain superfamily

IPR050853 WD repeat-containing DNA damage-binding protein
GlyGen

Molecular
Reagents

less

All nucleic 27

Microarray probesets 4

References

Summaries

Gene Ontology 4

Phenotypes 11
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;