The Arabidopsis CLAVATA2 gene encodes a receptor-like protein required for the stability of the CLAVATA1 receptor-like kinase - PubMed

The Arabidopsis CLAVATA2 gene encodes a receptor-like protein required for the stability of the CLAVATA1 receptor-like kinase

S Jeong et al. Plant Cell. 1999 Oct.

Abstract

The CLAVATA2 (CLV2) gene regulates both meristem and organ development in Arabidopsis. We isolated the CLV2 gene and found that it encodes a receptor-like protein (RLP), with a presumed extracellular domain composed of leucine-rich repeats similar to those found in plant and animal receptors, but with a very short predicted cytoplasmic tail. RLPs lacking cytoplasmic signaling domains have not been previously shown to regulate development in plants. Our prior work has demonstrated that the CLV1 receptor-like kinase (RLK) is present as a disulfide-linked multimer in vivo. We report that CLV2 is required for the normal accumulation of CLV1 protein and its assembly into protein complexes, indicating that CLV2 may form a heterodimer with CLV1 to transduce extracellular signals. Sequence analysis suggests that the charged residue in the predicted transmembrane domain of CLV2 may be a common feature of plant RLPs and RLKs. In addition, the chromosomal region in which CLV2 is located contains an extremely high rate of polymorphism, with 50 nucleotide and 15 amino acid differences between Landsberg erecta and Columbia ecotypes within the CLV2 coding sequence.

Similar articles

• CLAVATA2 forms a distinct CLE-binding receptor complex regulating Arabidopsis stem cell specification.

  Guo Y, Han L, Hymes M, Denver R, Clark SE. Guo Y, et al. Plant J. 2010 Sep;63(6):889-900. doi: 10.1111/j.1365-313X.2010.04295.x. Plant J. 2010. PMID: 20626648 Free PMC article.

• The receptor kinase CORYNE of Arabidopsis transmits the stem cell-limiting signal CLAVATA3 independently of CLAVATA1.

  Müller R, Bleckmann A, Simon R. Müller R, et al. Plant Cell. 2008 Apr;20(4):934-46. doi: 10.1105/tpc.107.057547. Epub 2008 Apr 1. Plant Cell. 2008. PMID: 18381924 Free PMC article.

• Synergistic interaction of CLAVATA1, CLAVATA2, and RECEPTOR-LIKE PROTEIN KINASE 2 in cyst nematode parasitism of Arabidopsis.

  Replogle A, Wang J, Paolillo V, Smeda J, Kinoshita A, Durbak A, Tax FE, Wang X, Sawa S, Mitchum MG. Replogle A, et al. Mol Plant Microbe Interact. 2013 Jan;26(1):87-96. doi: 10.1094/MPMI-05-12-0118-FI. Mol Plant Microbe Interact. 2013. PMID: 22835273

• The Multifunction of CLAVATA2 in Plant Development and Immunity.

  Pan L, Lv S, Yang N, Lv Y, Liu Z, Wu J, Wang G. Pan L, et al. Front Plant Sci. 2016 Oct 24;7:1573. doi: 10.3389/fpls.2016.01573. eCollection 2016. Front Plant Sci. 2016. PMID: 27822222 Free PMC article. Review.

• Signaling through the CLAVATA1 receptor complex.

  DeYoung BJ, Clark SE. DeYoung BJ, et al. Plant Mol Biol. 2001 Jul;46(5):505-13. doi: 10.1023/a:1010672910703. Plant Mol Biol. 2001. PMID: 11516143 Review. No abstract available.

Cited by

• Next Generation Cereal Crop Yield Enhancement: From Knowledge of Inflorescence Development to Practical Engineering by Genome Editing.

  Liu L, Lindsay PL, Jackson D. Liu L, et al. Int J Mol Sci. 2021 May 13;22(10):5167. doi: 10.3390/ijms22105167. Int J Mol Sci. 2021. PMID: 34068350 Free PMC article. Review.

• The Protein Phosphatases and Protein Kinases of Arabidopsis thaliana.

  Wang H, Chevalier D, Larue C, Ki Cho S, Walker JC. Wang H, et al. Arabidopsis Book. 2007;5:e0106. doi: 10.1199/tab.0106. Epub 2007 Feb 20. Arabidopsis Book. 2007. PMID: 22303230 Free PMC article. No abstract available.

• Knowing When to Silence: Roles of Polycomb-Group Proteins in SAM Maintenance, Root Development, and Developmental Phase Transition.

  Yan B, Lv Y, Zhao C, Wang X. Yan B, et al. Int J Mol Sci. 2020 Aug 15;21(16):5871. doi: 10.3390/ijms21165871. Int J Mol Sci. 2020. PMID: 32824274 Free PMC article. Review.

• Formation, maintenance and function of the shoot apical meristem in rice.

  Itoh J, Sato Y, Nagato Y, Matsuoka M. Itoh J, et al. Plant Mol Biol. 2006 Apr;60(6):827-42. doi: 10.1007/s11103-005-5579-3. Plant Mol Biol. 2006. PMID: 16724255 Review.

• Genomic identification of direct target genes of LEAFY.

  William DA, Su Y, Smith MR, Lu M, Baldwin DA, Wagner D. William DA, et al. Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1775-80. doi: 10.1073/pnas.0307842100. Epub 2004 Jan 21. Proc Natl Acad Sci U S A. 2004. PMID: 14736918 Free PMC article.

References

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • PubMed Central
  • Silverchair Information Systems

• Other Literature Sources

  • The Lens - Patent Citations Database

• Molecular Biology Databases

  • Gene Ontology
  • The Arabidopsis Information Resource