Advances in characterisation and biological activities of chitosan and chitosan oligosaccharides - PubMed

Affiliations

• PMID: 26213092
• DOI: 10.1016/j.foodchem.2015.06.076

Review

Advances in characterisation and biological activities of chitosan and chitosan oligosaccharides

Pan Zou et al. Food Chem. 2016.

Abstract

Chitosan and chitosan oligosaccharides (COS) have been reported to possess various biomedical properties, including antimicrobial activities, immuno-enhancing effects, and anti-tumour activities. COS have attracted considerable interest due to their physicochemical properties, and potential applications in the food and pharmaceutical industries, especially in cancer therapies. This paper describes the preparation of COS and their physicochemical properties, and modification, which aids understanding of their biological activities. Based on the latest reports, several biological and anti-tumour activities of COS will be discussed. The proposed anti-tumour mechanisms of COS are summarised, to provide comprehensive insights into research on the molecular level. Finally, the potential applications and future development of the biopolymer will be discussed.

Keywords: Anti-tumour; Biological activities; Chitosan; Chitosan oligosaccharides; Mechanism; Physicochemical.

Similar articles

• Chitosan oligosaccharide (COS): An overview.

  Naveed M, Phil L, Sohail M, Hasnat M, Baig MMFA, Ihsan AU, Shumzaid M, Kakar MU, Mehmood Khan T, Akabar MD, Hussain MI, Zhou QG. Naveed M, et al. Int J Biol Macromol. 2019 May 15;129:827-843. doi: 10.1016/j.ijbiomac.2019.01.192. Epub 2019 Jan 29. Int J Biol Macromol. 2019. PMID: 30708011 Review.

• Advances in the preparation, characterization, and biological functions of chitosan oligosaccharide derivatives: A review.

  Li B, Cui J, Xu T, Xu Y, Long M, Li J, Liu M, Yang T, Du Y, Xu Q. Li B, et al. Carbohydr Polym. 2024 May 15;332:121914. doi: 10.1016/j.carbpol.2024.121914. Epub 2024 Feb 6. Carbohydr Polym. 2024. PMID: 38431416 Review.

• Chitooligosaccharide and its derivatives: preparation and biological applications.

  Lodhi G, Kim YS, Hwang JW, Kim SK, Jeon YJ, Je JY, Ahn CB, Moon SH, Jeon BT, Park PJ. Lodhi G, et al. Biomed Res Int. 2014;2014:654913. doi: 10.1155/2014/654913. Epub 2014 Mar 3. Biomed Res Int. 2014. PMID: 24724091 Free PMC article. Review.

• Chitosan and Chitooligosaccharide: The Promising Non-Plant-Derived Prebiotics with Multiple Biological Activities.

  Guan Z, Feng Q. Guan Z, et al. Int J Mol Sci. 2022 Jun 17;23(12):6761. doi: 10.3390/ijms23126761. Int J Mol Sci. 2022. PMID: 35743209 Free PMC article. Review.

• Chitosan oligosaccharide: Biological activities and potential therapeutic applications.

  Muanprasat C, Chatsudthipong V. Muanprasat C, et al. Pharmacol Ther. 2017 Feb;170:80-97. doi: 10.1016/j.pharmthera.2016.10.013. Epub 2016 Oct 20. Pharmacol Ther. 2017. PMID: 27773783 Review.

Cited by

• Characterization and Antioxidant Activity of the Polysaccharide Hydrolysate from Lactobacillus plantarum LPC-1 and Their Effect on Spinach (Spinach oleracea L.) Growth.

  Yan ZX, Li M, Wei HY, Peng SY, Xu DJ, Zhang B, Cheng X. Yan ZX, et al. Appl Biochem Biotechnol. 2024 Sep;196(9):6151-6173. doi: 10.1007/s12010-023-04843-w. Epub 2024 Jan 9. Appl Biochem Biotechnol. 2024. PMID: 38194184

• The preparation and antioxidant activities of three phenyl-acylchitooligosaccharides.

  Liu Y, Wen F, Yang H, Bao L, Zhao Z, Zhong Z. Liu Y, et al. Heliyon. 2022 Sep 15;8(9):e10624. doi: 10.1016/j.heliyon.2022.e10624. eCollection 2022 Sep. Heliyon. 2022. PMID: 36164516 Free PMC article.

• Chitosan Versus Dapagliflozin in a Diabetic Cardiomyopathy Mouse Model.

  Târtea G, Popa-Wagner A, Sfredel V, Mitran SI, Dan AO, Țucă AM, Preda AN, Raicea V, Țieranu E, Cozma D, Vătășescu R. Târtea G, et al. Int J Mol Sci. 2024 Feb 9;25(4):2118. doi: 10.3390/ijms25042118. Int J Mol Sci. 2024. PMID: 38396795 Free PMC article.

• Chitosan and its derivatives regulate lactic acid synthesis during milk fermentation.

  Kurchenko V, Halavach T, Yantsevich A, Shramko M, Alieva L, Evdokimov I, Lodygin A, Tikhonov V, Nagdalian A, Ali Zainy FM, Al-Farga A, ALFaris NA, Shariati MA. Kurchenko V, et al. Front Nutr. 2024 Sep 16;11:1441355. doi: 10.3389/fnut.2024.1441355. eCollection 2024. Front Nutr. 2024. PMID: 39351492 Free PMC article.

• Review on Natural Preservatives for Extending Fish Shelf Life.

  Mei J, Ma X, Xie J. Mei J, et al. Foods. 2019 Oct 13;8(10):490. doi: 10.3390/foods8100490. Foods. 2019. PMID: 31614926 Free PMC article. Review.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science

• Other Literature Sources

  • The Lens - Patent Citations Database
  • scite Smart Citations