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The Good Scents Company - Aromatic/Hydrocarbon/Inorganic Ingredients Catalog information

CAS Number: 8015-79-0
FDA UNII: Search
CoE Number:13
Also Contains:acorus calamus root extract

Category:fragrance agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

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FDA Mainterm (SATF):8015-79-0 ; CALAMUS OIL--PROHIBITED
FDA Regulation:
FDA PART 189 -- SUBSTANCES PROHIBITED FROM USE IN HUMAN FOOD
Subpart C--Substances Generally Prohibited From Direct Addition or Use as Human Food
Sec. 189.110 Calamus and its derivatives.

Physical Properties:

Appearance:pale yellow clear liquid (est)
Food Chemicals Codex Listed: No
Soluble in:
 alcohol
Insoluble in:
 water
Similar Items:note
acorus calamus extract hydrogenated
acorus calamus l. rhizome oil
acorus calamus l. root extract
acorus calamus l. root oil
acorus calamus l. root oil mongolia
acorus calamus l. root powder

Organoleptic Properties:

Odor Type: spicy
spicy clove calamus
Odor Description:at 100.00 %. spicy clove
Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

Suppliers:

Safety Information:

 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-guinea pig LD50 297 mg/kg
BEHAVIORAL: TETANY BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Antibiotics and Chemotherapy Vol. 7, Pg. 378, 1957.

intraperitoneal-mouse LD50 177 mg/kg
Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 163, 1959.

intravenous-mouse LD50 1138 mg/kg
BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Dissertationes Pharmaceuticae. Vol. 16, Pg. 447, 1964.

intraperitoneal-rat LD50 221 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Food and Cosmetics Toxicology. Vol. 15, Pg. 623, 1977.

oral-rat LD50 777 mg/kg
BEHAVIORAL: TREMOR
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

Dermal Toxicity:
skin-guinea pig LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 15, Pg. 623, 1977.
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA fragrance material specification:
 cis- and trans-Asarone as such should not be used as fragrance ingredients; essential oils containing cis- or trans-asarone (e.g. calamus oils) should not be used at a level such that the total concentration of cis- and trans-asarone exceeds 0.01% in consumer products.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
methyl eugenol Max. Found: <0.90 % and Reason: Potential carcinogenic activity in animals
Recommendation for calamus leaf oil usage levels up to:
  3.0000 % in the fragrance concentrate.
 
Recommendation for calamus leaf oil flavor usage levels up to:
 not for flavor use.

Safety References:

Chemical Carcinogenesis Research Information System:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8015-79-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
acorus calamus l. leaf oil
Chemidplus:0008015790

References:

Other Information:

Potential Blenders and core components note

For Odor
No odor group found for these
linoleic acid
FL/FR

(E)-beta-

ocimene
FL/FR
tricosane
FR
balsamic
balsamic

beta-

bisabolene
FL/FR

dextro,laevo-

borneol
FL/FR
bornyl acetate
FL/FR

iso

bornyl isobutyrate
FL/FR
camphoreous

(±)-

camphor
FL/FR
cheesy
heptanoic acid
FL/FR
citrus
dipentene
FL/FR
floral
cassie absolute
FL/FR
linalool
FL/FR

(Z)-beta-

ocimene
FL/FR

(Z,E)-

phytol
FL/FR
hay
tobacco absolute replacer
FR
herbal
acorus calamus rhizome oil
FR
acorus calamus root oil
FR
acorus calamus root oil mongolia
FR

beta-

bourbonene
FL/FR

alpha-

cadinol
FL/FR
calamus oil replacer
FR

1,8-

cineole
FL/FR

delta-

elemene
FL/FR

beta-

elemene
FL/FR
linalyl acetate
FL/FR

T-

muurolol
FL/FR

beta-

pinene
FL/FR

alpha-

pinene
FL/FR
oily
methyl linolenate
FL/FR
spicy
allspice berry oil
FL/FR
allspice berry oil terpeneless
FL/FR
allspice leaf oil
FL/FR
allspice leaf oil terpeneless
FL/FR
allspice oil
FL/FR
allspice oleoresin
FL/FR
carvacrol
FL/FR

4-

carvomenthenol
FL/FR

beta-

caryophyllene
FL/FR
cinnamomum culilawan bark oil
FR
cinnamomum culilawan leaf oil
FR
cinnamon leaf oil replacer
FR
dihydroeugenol
FL/FR

4-

ethyl guaiacol
FL/FR
ethyl isoeugenol
FL/FR

iso

eugenol
FL/FR

iso

eugenyl phenyl acetate
FL/FR
laurus nobilis leaf oil turkey
FL/FR
methyl eugenol
FR

4-

methyl guaiacol
FL/FR
methyl isoeugenol
FL/FR
myrcene
FR
pimenta acris leaf oil
FL/FR
pimenta officinalis fruit extract
FR
terpenic

para-

cymene
FL/FR

alpha-

phellandrene
FL/FR

gamma-

terpinene
FL/FR

alpha-

terpineol
FL/FR
waxy
palmitic acid
FR
woody
camphene
FL/FR

alpha-

cedrene
FL/FR
cedrol
FL/FR

alpha-

farnesene
FL/FR

(E)-beta-

farnesene
FL/FR
guaiene
FL/FR
sabinene
FL/FR

alpha-

terpinene
FL/FR
For Flavor
No flavor group found for these

beta-

bisabolene
FL/FR

dextro,laevo-

borneol
FL/FR

beta-

bourbonene
FL/FR

alpha-

cadinol
FL/FR

alpha-

cedrene
FL/FR
dipentene
FL/FR

delta-

elemene
FL/FR

beta-

elemene
FL/FR

(E)-beta-

farnesene
FL/FR
laurus nobilis leaf oil turkey
FL/FR
linoleic acid
FL/FR
methyl linolenate
FL/FR

T-

muurolol
FL/FR

(E)-beta-

ocimene
FL/FR
balsamic
balsamic

iso

bornyl isobutyrate
FL/FR

(Z,E)-

phytol
FL/FR
camphoreous
bornyl acetate
FL/FR
camphene
FL/FR

(±)-

camphor
FL/FR
citrus
linalool
FL/FR

alpha-

terpineol
FL/FR
cooling

4-

carvomenthenol
FL/FR
floral
linalyl acetate
FL/FR
green

alpha-

farnesene
FL/FR

(Z)-beta-

ocimene
FL/FR
minty

1,8-

cineole
FL/FR
pine

beta-

pinene
FL/FR
spicy
allspice berry oil
FL/FR
allspice berry oil terpeneless
FL/FR
allspice leaf oil
FL/FR
allspice leaf oil terpeneless
FL/FR
allspice oil
FL/FR
allspice oleoresin
FL/FR
carvacrol
FL/FR

beta-

caryophyllene
FL/FR
cassie absolute
FL/FR
dihydroeugenol
FL/FR
ethyl isoeugenol
FL/FR

iso

eugenol
FL/FR

iso

eugenyl phenyl acetate
FL/FR

4-

methyl guaiacol
FL/FR
methyl isoeugenol
FL/FR
pimenta acris leaf oil
FL/FR
terpenic

para-

cymene
FL/FR

alpha-

phellandrene
FL/FR

alpha-

terpinene
FL/FR

gamma-

terpinene
FL/FR
waxy
heptanoic acid
FL/FR
woody
cedrol
FL/FR

4-

ethyl guaiacol
FL/FR
guaiene
FL/FR

alpha-

pinene
FL/FR
sabinene
FL/FR

Potential Uses:

Occurrence (nature, food, other):note

Synonyms:

 acorus americanus leaf oil
 acorus angustatus leaf oil
 acorus angustifolius leaf oil
 acorus asiaticus leaf oil
 acorus calamus leaf oil
 acorus calamus var. americanus leaf oil
 acorus calamus var. angustatus leaf oil
 acorus calamus var. angustifolius leaf oil
 acorus calamus var. spurius leaf oil
 acorus calamus var. verus leaf oil
 acorus calamus var. vulgaris leaf oil
 acorus cochinchinensis leaf oil
 acorus griffithii leaf oil
 acorus spurius leaf oil
 acorus triqueter leaf oil
 acorus verus leaf oil
 orontium cochinchinense leaf oil

Articles:

PubMed:Assessment of litter degradation in medicinal plants subjected to ultraviolet-B radiation.
PubMed:Chemical compositions, phytotoxicity, and biological activities of Acorus calamus essential oils from Nepal.
PubMed:Identification, characterization, and palynology of high-valued medicinal plants.
PubMed:Effects of perchlorate on growth of four wetland plants and its accumulation in plant tissues.
PubMed:[Influence of perennial flooding and drought on growth restoration of Acorus calamus in water-level-fluctuation zone of the Three Gorges Reservoir].
PubMed:Efficacy of natural products against Callosobruchus chinensis (Coleoptera: Bruchidae) in Nepal.
PubMed:Terpenoid composition and antifungal activity of three commercially important essential oils against Aspergillus flavus and Aspergillus niger.
PubMed:Anti-inflammatory activity of a water extract of Acorus calamus L. leaves on keratinocyte HaCaT cells.
PubMed:Antifungal properties of haem peroxidase from Acorus calamus.
PubMed:Long-term anoxia tolerance in leaves of Acorus calamus L. and Iris pseudacorus L.