thegoodscentscompany.com

The Good Scents Company - Aromatic/Hydrocarbon/Inorganic Ingredients Catalog information

2-isobutyl thiazole
2-isobutylthiazole

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  • Augustus Oils

    The Premier Supplier
    Augustus Oils Ltd, in harmony with nature - to present it at its best...
    A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements.
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    Product(s):
    2 Iso Butyl Thiazole
  • Beijing Lys Chemicals

    From Grams to Tons
    Fine chemical high-tech company which contains R&D, production, and sales.
    BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
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    Product(s):
    10089 2-isoButylthiazole
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    Product(s):
    18640-74-9 2-isoButyl Thiazole 98%
  • Charkit Chemical

    The Specialty Chemical Specialists
    Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
    about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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    Product(s):
    ISOBUTYLTHIAZOLE, 2- 1% IN DPG
    ISOBUTYLTHIAZOLE, 2- FEMA 3134
  • Endeavour Specialty Chemicals

    Expertise in high impact aroma chemicals
    Endeavour Speciality Chemicals offers high-impact aroma chemicals, at small to medium scale.
    Speciality Chemical has more than 25 years experience of manufacturing high-impact aroma chemicals. With our core expertise in sulfur and heterocyclic chemistries, Endeavours products have applications in a range of industry sectors including flavours and fragrances, pharmaceutical research and material sciences. Endeavour also offer custom synthesis and contract manufacturing services at their UK manufacturing site.
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    Product(s):
    TZ0060 2-Isobutylthiazole 97% F&F
  • Frutarom

    Flavor & Specialty Ingredients
    Your preferred partner for flavour and fragrance success.
    Our broad and diverse product portfolio is designed to provide and cater for every flavor and taste profile required by our customer base and incorporates historic, and iconic, market leading products.
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    Product(s):
    441I110000 2-ISOBUTYLTHIAZOLE KOSHER
  • Indukern F&F

  • Jiangyin Healthway

    Independent Ingredients Supplier
    We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
    Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
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    Product(s):
    HL0145 2-IsoButyl Thiazole
  • Lluch Essence

    A family company dedicated to sales and distribution
    Flexibility, availability, price and quality.
    Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
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    Product(s):
    2-ISOBUTYL THIAZOLE
  • M&U International

    Steady supply & demand
    Meeting customers increasing demands at home as well as abroad.
    M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
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    Product(s):
    H0067 2-isoBUTYL THIAZOLE, Kosher
  • Natural Advantage

  • Pell Wall Perfumes

    Hand-made fragrances
    Pell Wall maintains a broad palette of ingredients & in order to keep stocks fresh & the options wide we also sell from our own stock.
    Pell Wall was founded by perfumer Chris Bartlett to provide exclusive hand-made fragrances to a select few people who love them. All our products are created using fine quality ingredients, many of which we also offer for sale to other perfumers and enthusiasts. Pell Wall make fragrances for men, for women and for the home.
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    Isobutylthiazole
    A very interesting material that, when sufficiently diluted gives an extremely realistic note of tomatoes – with the addition of other components it can easily be pushed in the direction of ripe tomato fruits or that characteristic smell of the tomato plant itself.
  • Penta International

    Chemistry innovation
    At Penta, our products and services help businesses do business better.
    For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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    Product(s):
    09-45100 2-ISOBUTYL THIAZOLE
    09-45120 2-ISOBUTYLTHIAZOLE NATURAL
  • Riverside Aromatics

    Speciality Aroma Chemicals, Naturals and Synthetics
    A specialist supplier of raw materials to the flavour industry.
    Peter Cannon & David Rowe established Riverside Aromatics in 2006 in Poole, UK, to offer a new type of specialist raw material supplier to the Flavour & Fragrance Industry. We bring together over 40 years of commercial & technical experience in the F&F industry which allows us to understand the needs of the Global F&F business and especially that of the West European Market.
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    Product(s):
    IT0100 2-isoBUTYLTHIAZOLE
    NI2001 2-isoBUTYLTHIAZOLE NATURAL 1% IN PG
    NI2000 2-ISOBUTYLTHIAZOLE, NATURAL
  • Robinson Brothers

  • Sigma-Aldrich

  • SRS Aromatics

    For over 25 years
    Bringing flavour and fragrance into your world.
    As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
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    Product(s):
    THIAZYL 1% DPG
  • Sunaux International

    Buy With Confidence
    We have industry leading processes and procedures to ensure nothing but the most reliable product.
    Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business.
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    Product(s):
    H0067 2-isoButyl Thiazole
  • Synerzine

    Innovation. Customization. Aroma Ingredients.
    Synerzine is a leading supplier of flavor and fragrance ingredients.
    Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
    Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
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    Products List:View
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    Product(s):
    T712 2-isobutylthiazole nick-named Tomato Leaf Thiazole
  • Taytonn ASCC

    Supplying Asia Pacific
    We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.
    Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers.
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    Product(s):
    2-isoButylthiazole
  • TCI AMERICA

    Moving Your Chemistry Forward
    We continuously strive to advance our technology.
    With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
    Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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    Product(s):
    I0652 2-isoButylthiazole >97.0%(GC)
    SDS
  • The John D. Walsh Company

    Suppliers Since 1942
    Supplying the fragrance and flavor industry with high quality products.
    The John D. Walsh Company, Inc. has evolved from its beginnings as an agent/broker into a distributor of essential oils, aroma chemicals, concretes and absolutes. We currently represent the following companies, as their North American distributor: Destilerias Munoz Galvez, S.A. International Flavors & Fragrances PFW Aroma Chemicals B.V. Innospec Widnes Limited Hydrodiffusion de Guatemala, S. A. DSM Nutritional Products The John D. Walsh Company, Inc. is proud to be a founding member of IFEAT, an active member of IFRA, North America, and a corporate sponsor of the WFFC.
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    973-962-1400

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    973-962-1557

    Firmenich Flavor Phone:973-962-1888
    Firmenich Flavor Fax:973-962-1898
    History
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    Product(s):
    Thiazyl 1% in DPG
    SDS
  • Tianjin Danjun International

    Quality Products
    We know the Chinese chemical market well.
    Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service.
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    +86-15822601686

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    Product(s):
    B-038 2-Isobutylthiazole
  • R C Treatt & Co Ltd

    Innovative ingredient solutions
    World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
    We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
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    +44 (0) 1284 702500

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    +1 863 668 3388

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    Product(s):
    2-Isobutylthiazole Halal, Kosher
    Odor threshold in water: 2-3.5 ppb.
    Effective in enhancing tomato juice at 25-50 ppb. Useful for enhancing Tomato flavor of condiments (e.g., Ketchup). This compound is essential to the flavor of Tomato. Normal use levels in finished consumer product: 0.02-1.0 ppm.
    2-Isobutylthiazole 1% in DPG Kosher
  • United International

    Quality Products
    A partner in your supply chain solution.
    Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
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    +86-532-83893699

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    +86-532-83893695

    GSC100537102917 GSC100537102917
    Product(s):
    2010 2-Isobutyl Thiazole
    2010N 2-Isobutyl Thiazole Nat.
  • Ernesto Ventós

  • Vigon International

    Passion for Simplicity
    Manufacturer and supplier of high quality flavor and fragrance ingredients.
    The growth and success of Vigon is due in large part to a unique corporate concept that Vigon has developed and established within the industry: Creative Partnerships. This partnership concept has been and continues to be the foundation and guiding principle for all of Vigon's activities.
    US Email:Sales
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    570-476-6300

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    Product(s):
    501355 Isobutyl-2 Thiazole
  • WholeChem

    Connecting Innovators To the Building Blocks Of the Universe
    Custom manufacturer and distributor of specialty ingredients. We make global local.
    SQF-Certified Supplier
    We owe our success to our integrity, our dedication to the industry, and our commitment to our clients. We invite your inquiries regarding our current product list and any other products you may be having trouble sourcing.
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    GSC100537102917 GSC100537102917
    Product(s):
    2-Isobutyl thiazole
Fragrance Demo Formulas
Flavor Demo Formulas
Name:2-(2-methylpropyl)-1,3-thiazole
CAS Number: 18640-74-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:242-470-1
FDA UNII: 7N03TDY75D
Nikkaji Web:J45.613F
MDL:MFCD00005334
CoE Number:11618
XlogP3-AA:2.60 (est)
Molecular Weight:141.23667000
Formula:C7 H11 N S
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)

Category: flavor and fragrance agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:1034 2-isobutylthiazole
DG SANTE Food Flavourings:15.013 2-isobutylthiazole
FEMA Number:3134 2-isobutylthiazole
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.

Physical Properties:

Appearance:colorless to pale yellow clear liquid (est)
Assay: 96.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.99500 to 0.99530 @ 25.00 °C.
Pounds per Gallon - (est).: 8.279 to 8.282
Specific Gravity:1.00000 to 1.00400 @ 20.00 °C.
Pounds per Gallon - est.: 8.331 to 8.364
Refractive Index:1.49400 to 1.49800 @ 20.00 °C.
Refractive Index:1.49000 to 1.49900 @ 20.00 °C.
Boiling Point: 174.00 to 180.00 °C. @ 760.00 mm Hg
Vapor Pressure:1.091000 mmHg @ 25.00 °C. (est)
Vapor Density:4.8 ( Air = 1 )
Flash Point: 135.00 °F. TCC ( 57.22 °C. )
logP (o/w): 1.715 (est)
Soluble in:
 alcohol
 water, 255.2 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 stable in most media

Organoleptic Properties:

Odor Type: green
Odor Strength:high ,
recommend smelling in a 0.10 % solution or less
Substantivity: > 1 hour(s) at 100.00 %
green wasabi privet tomato leaf earthy vegetable metallic
Odor Description:at 1.00 % in dipropylene glycol. green wasabi privet tomato leaf earthy vegetable metallic
Luebke, William tgsc, (2009)
Odor sample from: R C Treatt and Co Ltd
green vegetable musty waxy
Odor Description:Green, vegetable, musty with a waxy nuance
Mosciano, Gerard P&F 17, No. 4, 33, (1992)
Flavor Type: green
green vegetable tomato raw musty
Taste Description: at 2.00 ppm. Green, vegetable, tomato-like with raw musty nuances
Mosciano, Gerard P&F 17, No. 4, 33, (1992)
Odor and/or flavor descriptions from others (if found).
R C Treatt & Co Ltd
2-Isobutylthiazole Halal, Kosher
Odor Description:Green tomato leaf
Odor threshold in water: 2-3.5 ppb.
Taste Description:Green tomato
Effective in enhancing tomato juice at 25-50 ppb. Useful for enhancing Tomato flavor of condiments (e.g., Ketchup). This compound is essential to the flavor of Tomato. Normal use levels in finished consumer product: 0.02-1.0 ppm.
Pell Wall Perfumes
Isobutylthiazole
Odor Description:Green, tomato, earthy, vegetable, metallic. Extremely powerful
A very interesting material that, when sufficiently diluted gives an extremely realistic note of tomatoes � with the addition of other components it can easily be pushed in the direction of ripe tomato fruits or that characteristic smell of the tomato plant itself.
Perfumery Laboratory
Tomato leaf thiazol 0.1% in DPG PFW (Tomato leaf thiazole 0.1% PFW)
Odor Description:Powerful, fresh, natural, tomato, earthy

Cosmetic Information:

Suppliers:

Advanced Biotech
2-ISOBUTYL THIAZOLE NATURAL
Advanced Biotech
2-ISOBUTYL THIAZOLE

Odor: Tomato leaf

Advanced Biotech
ISO BUTYL THIAZOLE 1% ETOH NATURAL
Advanced Biotech
ISOBUTYL THIAZOLE 1% WS NATURAL

Odor: Tomato leaf

Ambles Nature et Chimie
2-ISOBUTYL THIAZOLE
Anhui Suzhou Jinli Aromatic Chemicals
2-isoButyl Thiazole

Odor: tomato

Augustus Oils
2 Iso Butyl Thiazole
Services
Beijing Lys Chemicals
2-isoButylthiazole
BOC Sciences
For experimental / research use only.
2-isoButyl Thiazole 98%
Charkit Chemical
ISOBUTYLTHIAZOLE, 2- 1% IN DPG
Charkit Chemical
ISOBUTYLTHIAZOLE, 2- FEMA 3134
DeLong Chemicals America
2-Isobutylthiazole, Kosher
Endeavour Specialty Chemicals
2-Isobutylthiazole 97% F&F
Speciality Chemical Product Groups
Ernesto Ventós
2-isoBUTYLTHIAZOLE

Odor: TOMATO LEAVES, MUSHROOM, EARTHY

Frutarom
2-ISOBUTYLTHIAZOLE

KOSHER

Flavor: Fresh, Green, Tomato, Vinous, Musty

CBD Offering
IFF
2-ISOBUTYLTHIAZOLE

KOSHER

Flavor: Fresh, Green, Tomato, Vinous, Musty

Indukern F&F
2-ISOBUTYL THIAZOLE

Odor: GREEN TOMATO LEAF, WOODY

Jiangyin Healthway
2-IsoButyl Thiazole
New functional food ingredients
Jinan Enlighten Chemical Technology(Wutong Aroma )
2-isoButyl thiazole, Kosherk
Kingchem Laboratories
2-ISOBUTYLTHIAZOLE

Odor: Tomato-like

Lluch Essence
2-ISOBUTYL THIAZOLE

Odor: WOODY, TOMATO-LEAF NOTES

M&U International
2-isoBUTYL THIAZOLE, Kosher
Natural Advantage
Isobutylthiazole Nat, 1% in Neobee

Flavor: green, musky, tomato

Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries
Natural Advantage
Isobutylthiazole Nat, 1% in OH

Flavor: green, musky, tomato

Natural Advantage
Isobutylthiazole Nat, 1% in PG

Flavor: green, musky, tomato

Natural Advantage
Isobutylthiazole Nat, 10% in Triacetin Nat USOC

Flavor: green, musky, tomato

Natural Advantage
Isobutylthiazole Nat, 10% in Triacetin

Flavor: green, musky, tomato

Natural Advantage
Isobutylthiazole

Flavor: green, musky, tomato

PCW France
Thiazyl 1% DPG
Steps to a fragranced product
Pearlchem Corporation
2-isoButyl Thiazole
Pell Wall Perfumes
Isobutylthiazole

Odor: Green, tomato, earthy, vegetable, metallic. Extremely powerful

Use: A very interesting material that, when sufficiently diluted gives an extremely realistic note of tomatoes � with the addition of other components it can easily be pushed in the direction of ripe tomato fruits or that characteristic smell of the tomato plant itself.

Penta International
2-ISOBUTYL THIAZOLE
Penta International
2-ISOBUTYLTHIAZOLE NATURAL
Perfumery Laboratory
Tomato leaf thiazol 0.1% in DPG PFW (Tomato leaf thiazole 0.1% PFW)

Odor: Powerful, fresh, natural, tomato, earthy

R C Treatt & Co Ltd
2-Isobutylthiazole 1% in DPG

Kosher

R C Treatt & Co Ltd
2-Isobutylthiazole

Halal, Kosher

Odor: Green tomato leaf

Use: Odor threshold in water: 2-3.5 ppb.

Flavor: Green tomato

Effective in enhancing tomato juice at 25-50 ppb. Useful for enhancing Tomato flavor of condiments (e.g., Ketchup). This compound is essential to the flavor of Tomato. Normal use levels in finished consumer product: 0.02-1.0 ppm.

Reincke & Fichtner
2-isoButylthiazole
Riverside Aromatics
2-isoBUTYLTHIAZOLE NATURAL 1% IN PG
Riverside Aromatics
2-ISOBUTYLTHIAZOLE, NATURAL
Riverside Aromatics
2-isoBUTYLTHIAZOLE
Robinson Brothers
2-IsoButylthiazole F&F
https://www.robinsonbrothers.uk/chemistry-competences
Santa Cruz Biotechnology
For experimental / research use only.
2-isoButylthiazole
Sigma-Aldrich
2-Isobutylthiazole, ≥99%, FG

Odor: green; vegetable

Certified Food Grade Products
SRS Aromatics
THIAZYL 1% DPG
Sunaux International
2-isoButyl Thiazole
Synerzine
2-isobutylthiazole

nick-named Tomato Leaf Thiazole

Taytonn ASCC
2-isoButylthiazole

Odor: Vinous, Green, Fresh, Tomato

TCI AMERICA
For experimental / research use only.
2-isoButylthiazole >97.0%(GC)
Tengzhou Jitian Aroma Chemiclal
2-isoButyl Thiazole
Tengzhou Xiang Yuan Aroma Chemicals
2-isoButyl Thiazole
The John D. Walsh Company
Thiazyl 1% in DPG
Tianjin Danjun International
2-Isobutylthiazole
United International
2-Isobutyl Thiazole Nat.
United International
2-Isobutyl Thiazole
Vigon International
Isobutyl-2 Thiazole

Odor: GREEN, NUTTY

WholeChem
2-Isobutyl thiazole

Safety Information:

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2-isobutyl thiazole usage levels up to:
  0.0800 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 3.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.40 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 4
Click here to view publication 4
 average usual ppmaverage maximum ppm
baked goods: -1.00000
beverages(nonalcoholic): -1.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.00000
fruit ices: -1.00000
gelatins / puddings: -1.00000
granulated sugar: --
gravies: -1.00000
hard candy: -1.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -1.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: -1.00000
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -1.00000
sugar substitutes: --
sweet sauces: --

Safety References:

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 21: Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29. Miscellaneous substances from chemical group 30. (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 76, (FGE.76)[1] - Consideration of sulphur-containing heterocyclic compounds evaluated by JECFA (59th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29, miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 21, Revision 1 (FGE.21Rev1): Thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29 Miscellaneous substances from chemical group 30
View page or View pdf
Scientific Opinion on the safety and efficacy of thiazoles, thiophene, thiazoline and thienyl derivatives (chemical group 29): 3-acetyl-2,5-dimethylthiophene when used as a flavouring for all animal species
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 76, Revision 1 (FGE.76Rev1): Consideration of sulphur-containing heterocyclic compounds evaluated by JECFA (59th meeting) structurally related to thiazoles, thiophene, thiazoline and thienyl derivatives from chemical group 29 and miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21Rev3
View page or View pdf
Safety and efficacy of thiazoles, thiophene and thiazoline belonging to chemical group 29 when used as flavourings for all animal species
View page or View pdf
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):18640-74-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :62725
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 1993
WGK Germany:3
2-(2-methylpropyl)-1,3-thiazole
Chemidplus:0018640749
RTECS:XJ5103412 for cas# 18640-74-9

References:

 2-(2-methylpropyl)-1,3-thiazole
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:18640-74-9
Pubchem (cid):62725
Pubchem (sid):135021306
Flavornet:18640-74-9
Pherobase:View

Other Information:

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB31862
FooDB:FDB008546
YMDB (Yeast Metabolome Database):YMDB01585
Export Tariff Code:2934.10.0090
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View

Potential Blenders and core components note

For Odor
alliaceous
dibutyl sulfide
FL/FR
dipropyl disulfide
FL/FR
amber
amber furan
FR
balsamic
tetrahydrofurfuryl cinnamate
FL/FR
caramellic

2-iso

butyl-3-methyl pyrazine
FL/FR
cheesy

S-(

methyl thio) butyrate
FL/FR
chocolate

2,4,5-

trimethyl thiazole
FL/FR
citrus
methyl heptenone
FL/FR
petitgrain combava oil
FR
coumarinic
phthalide
FL/FR
ethereal

2-

methyl valeraldehyde
FL/FR
fatty

2-

nonenal
FL/FR

(E)-2-

octenal
FL/FR
floral
allyl anthranilate
FL/FR
geranium dihydropyran
FR
methyl dihydrojasmonate
FL/FR

bitter

orangeflower absolute morocco
FL/FR
petitgrain lemon oil
FL/FR
rose absolute (rosa damascena) bulgaria
FL/FR

laevo-

rose oxide
FL/FR

(Z)-

rose oxide
FL/FR
fruity

2-

hexen-1-ol
FL/FR

(E)-2-

hexen-1-ol
FL/FR
hexyl acetate
FL/FR

gamma-

undecalactone (aldehyde C-14 (so-called))
FL/FR
green
acetaldehyde butyl phenethyl acetal
FL/FR
acetaldehyde di-(Z)-3-hexen-1-yl acetal
FL/FR
acetaldehyde ethyl phenethyl acetal
FL/FR

iso

butyl methyl ketone
FL/FR
cortex pyridine
FL/FR
cumin acetaldehyde
FL/FR

3,5,6-neo

cyclocitral
FR
diphenyl oxide
FL/FR
galbanum decatriene
FL/FR
galbanum oil terpeneless
FL/FR
galbanum oleoresin
FL/FR
geranium absolute
FL/FR
geranium thiazole
FL/FR

1-

hepten-3-ol
FL/FR
heptyl cinnamate
FL/FR

3-

hexen-1-ol
FL/FR

(Z)-4-

hexen-1-ol
FL/FR

(Z)-2-

hexen-1-ol
FL/FR

(E)-2-

hexen-1-yl acetate
FL/FR

(Z)-3-

hexen-1-yl benzoate
FL/FR

(Z)-3-

hexen-1-yl lactate
FL/FR

(Z)-3-

hexen-1-yl methyl carbonate
FL/FR

(Z)-3-

hexen-1-yl tiglate
FL/FR

3-

hexenal
FL/FR
hexoxyacetaldehyde dimethyl acetal
FR
hexyl heptanoate
FL/FR

(Z)-

leaf acetal
FL/FR
leafy acetal
FL/FR
leafy oxime
FR
methyl heptine carbonate
FL/FR
narcissus flower absolute
FR
nerol oxide
FL/FR

(Z,Z)-3,6-

nonadien-1-ol
FL/FR

(E,Z)-2,6-

nonadien-1-yl acetate
FL/FR
octanal dimethyl acetal
FL/FR

(Z)-5-

octen-1-yl propionate
FL/FR

1-

penten-3-ol
FL/FR

(E)-2-

pentenal
FL/FR

2-

pentenal
FL/FR
phenoxyacetaldehyde 50% in benzyl alcohol
FR

3-

phenyl propionaldehyde
FL/FR

iso

propyl phenyl propionaldehyde
FR
rose leaf absolute (rosa centifolia)
FL/FR
styralyl acetate
FL/FR
herbal
anthemis nobilis flower oil roman
FL/FR

sweet

basil absolute
FL/FR

3-

butylidene phthalide
FL/FR

iso

dihydrolavandulal
FL/FR
herbal heptane
FR
rosemary oleoresin
FL/FR
minty

iso

pulegyl formate
FL/FR
musty
cocoa butenal
FL/FR
nutty
shoyu pyrazine
FL/FR

2,3,5-

trimethyl pyrazine
FL/FR
pine
plectranthus glandulosus hook f. leaf oil cameroon
FR
sulfurous
dimethyl sulfide
FL/FR
ethyl methyl mercaptopropionate
FL/FR
methyl 3-(methyl thio) propionate
FL/FR

3-(

methyl thio) hexanol
FL/FR
tomato
tomato essence
FL/FR
tomato specialty
FR
vegetable
methional
FL/FR
woody

alpha-

farnesene
FL/FR

alpha-

farnesene isomer
FL/FR
yeasty

2-

octen-4-one
FL/FR
For Flavor
No flavor group found for these
acetaldehyde di-(Z)-3-hexen-1-yl acetal
FL/FR
allyl anthranilate
FL/FR

2-

ethyl-4,5-dimethyl oxazole
FL
heptyl cinnamate
FL/FR

3-

hexen-1-ol
FL/FR

2-

hexenal
FL

(E)-2-

hexenal
FL
hexyl heptanoate
FL/FR

3-

methyl-3-pentanol
FL

2-

pentenal
FL/FR

iso

pulegyl formate
FL/FR
tetrahydrofurfuryl cinnamate
FL/FR
alliaceous
alliaceous
allyl thiopropionate
FL
dipropyl disulfide
FL/FR
aromatic
leafy acetal
FL/FR
celery

3-

butylidene phthalide
FL/FR
citrus
petitgrain lemon oil
FL/FR
coumarinic
phthalide
FL/FR
creamy

gamma-

undecalactone (aldehyde C-14 (so-called))
FL/FR
fatty

(Z)-3-

hexen-1-yl benzoate
FL/FR

1-

methyl thio-3-octanone
FL

2-

nonenal
FL/FR

(E)-2-

octenal
FL/FR
fermented
methyl thio isovalerate
FL
floral
methyl dihydrojasmonate
FL/FR

bitter

orangeflower absolute morocco
FL/FR
rose absolute (rosa damascena) bulgaria
FL/FR

laevo-

rose oxide
FL/FR
fruity

2,4-

hexadien-1-ol
FL

2-

hexen-1-ol
FL/FR
hexyl acetate
FL/FR
styralyl acetate
FL/FR
green
acetaldehyde butyl phenethyl acetal
FL/FR
acetaldehyde ethyl phenethyl acetal
FL/FR

iso

butyl methyl ketone
FL/FR

2-iso

butyl-3-methyl pyrazine
FL/FR
cocoa butenal
FL/FR
cortex pyridine
FL/FR
cumin acetaldehyde
FL/FR
dibutyl sulfide
FL/FR
dihydroxyacetophenone (mixed isomers)
FL
diphenyl oxide
FL/FR

alpha-

farnesene
FL/FR

alpha-

farnesene isomer
FL/FR
galbanum decatriene
FL/FR
galbanum oil terpeneless
FL/FR
galbanum oleoresin
FL/FR
geranium absolute
FL/FR
geranium thiazole
FL/FR

1-

hepten-3-ol
FL/FR

(E)-2-

hexen-1-ol
FL/FR

(Z)-2-

hexen-1-ol
FL/FR

(Z)-4-

hexen-1-ol
FL/FR

(E)-2-

hexen-1-yl acetate
FL/FR

(Z)-3-

hexen-1-yl lactate
FL/FR

(Z)-3-

hexen-1-yl methyl carbonate
FL/FR

(Z)-3-

hexen-1-yl tiglate
FL/FR

3-

hexenal
FL/FR

2-

hexyl pyridine
FL
horseradish oil
FL

(Z)-

leaf acetal
FL/FR
methyl heptenone
FL/FR
methyl heptine carbonate
FL/FR

4-

methyl thiazole
FL
nerol oxide
FL/FR

(E,Z)-2,6-

nonadien-1-yl acetate
FL/FR
octanal dimethyl acetal
FL/FR

(Z)-5-

octen-1-yl propionate
FL/FR

4-

penten-1-yl acetate
FL

1-

penten-3-ol
FL/FR

(E)-2-

pentenal
FL/FR

3-

phenyl propionaldehyde
FL/FR
propylene glycol acetone ketal
FL
rose leaf absolute (rosa centifolia)
FL/FR

(Z)-

rose oxide
FL/FR
herbal
anthemis nobilis flower oil roman
FL/FR

sweet

basil absolute
FL/FR

iso

dihydrolavandulal
FL/FR
rosemary oleoresin
FL/FR
metallic

2,5-

dihydroxy-1,4-dithiane
FL

3-(

methyl thio) hexanol
FL/FR
musty

S-(

methyl thio) butyrate
FL/FR
shoyu pyrazine
FL/FR

2,3,5-

trimethyl pyrazine
FL/FR
nutty

2,4,5-

trimethyl thiazole
FL/FR
onion
methyl propyl disulfide
FL
sulfurous
dimethyl sulfide
FL/FR
ethyl methyl mercaptopropionate
FL/FR
ethyl methyl sulfide
FL
potato butanone
FL
tomato
methional
FL/FR
tomato essence
FL/FR
vegetable
methyl 3-(methyl thio) propionate
FL/FR

2-

methyl valeraldehyde
FL/FR

2-

octen-4-one
FL/FR
potato butyraldehyde
FL
radish isothiocyanate
FL
waxy

(Z,Z)-3,6-

nonadien-1-ol
FL/FR

Potential Uses:

FRapricot
FRearth
FRfloral
FRfungus
FRgreen
 leaf
FRmusk
FRpeach
FLtomato
FRtomato leaf
FLvegetable
 vine

Occurrence (nature, food, other):note

Synonyms:

2-isobutyl-1,3-thiazole
isobutyl-2 thiazole
2-isobutylthiazole
isobutylthiazole
2-(2-methyl propyl) thiazole
2-(2-methylpropyl)-1,3-thiazole
2-(2-methylpropyl)thiazole
 thiazole, 2-(2-methylpropyl)-
 thiazole, 2-isobutyl-
 thiazyl (PFW)
 thiazyl 1% DPG (PFW)
 thiazyl 1% in DPG (PFW)
 tomato leaf thiazole

Articles:

PubMed:Impact of different distribution scenarios and recommended storage conditions on flavor related quality attributes in ripening fresh tomatoes.
PubMed:Dynamics of odorant binding to thin aqueous films of rat-OBP3.
PubMed:Flavor release of the tomato flavor enhancer, 2-isobutylthiazole, from whey protein stabilized model dressings.
PubMed:Population pharmacokinetic model for a novel oral hypoglycemic formed in vivo: comparing the use of active metabolite data alone versus using data of upstream and downstream metabolites.
PubMed:Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase.
PubMed:Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells.
PubMed:P2Y2 receptor-Gq/11 signaling at lipid rafts is required for UTP-induced cell migration in NG 108-15 cells.
PubMed:Comparison of tomatillo and tomato volatile compounds in the headspace by selected ion flow tube mass spectrometry (SIFT-MS).
PubMed:The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor.
PubMed:Studies on the aroma of five fresh tomato cultivars and the precursors of cis- and trans-4,5-epoxy-(E)-2-decenals and methional.
PubMed:A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo.
PubMed:MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes.
PubMed:Nitric oxide donating nonsteroidal anti-inflammatory drugs induce apoptosis in human prostate cancer cell systems and human prostatic stroma via caspase-3.
PubMed:First synthesis of an amythiamicin pyridine cluster.
PubMed:Absolute configuration of 2-sec-butyl-4,5-dihydrothiazole in male mouse urine.
PubMed:CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
PubMed:Differential effects of tomato (Lycopersicon esculentum mill) matrix on the volatility of important aroma compounds.
PubMed:Addition of heteroaromatics to alkylidenecyclopropanes catalyzed by palladium.
PubMed:Odorants of different chemical classes interact with distinct odorant binding protein subtypes.
PubMed:Synthesis and dopamine receptor modulating activity of substituted bicyclic thiazolidine lactam peptidomimetics of L-prolyl-L-leucyl-glycinamide.
PubMed:Mammalian pheromones VIII Chemical characterization of preorbital gland secretion of grey duiker,Sylvicapra grimmia (Artiodactyla: Bovidae).
PubMed:Mammalian pheromone studies, VII. Identification of thiazole derivatives in the preorbital gland secretions of the grey duiker, Sylvicapra grimmia, and the red duiker, Cephalophus natalensis.
PubMed:The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants.

Notes:

isolated from preorbital gland of the grey duiker, sylvicapra grimmia and the red duiker, cephalophus natalensis. Tomato volatile and flavouring ingredient. Liq. with tomato leaf odour