The Clinical Proteomic Technologies for Cancer | Details for CPTC-CEACAM8-2

Background

Catalog Number:

CPTC-CEACAM8-1

Target Antigen:

CEA Cell Adhesion Molecule 8 Peptide 1

Isotype:

IgG

Species:

Mouse Monoclonal Antibody

Last Updated:

10/20/2023

Antigen Recognition(s):

Peptide

Characterization Data [Compare Characterization Data]

Background

NCI Identification Number:

00471

Antigen Name:

CEA Cell Adhesion Molecule 8 Peptide 1

CPTC Name:

CPTC-CEACAM8 Peptide 1

Aliases:

CEA Cell Adhesion Molecule 8; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8; Carcinoembryonic Antigen Related Cell Adhesion Molecule 8; Non-Specific Cross-Reacting Antigen NCA-95; Carcinoembryonic Antigen CGM6; CD67 Antigen; CD66b; CGM6; Carcinoembryonic Antigen Gene Family Member 6; CD66b Antigen; CEACAM8; NCA-95; CD67

Function:

CEACAM8 (CEA Cell Adhesion Molecule 8) is a Protein Coding gene. Diseases associated with CEACAM8 include Hemoglobinuria and Paroxysmal Nocturnal Hemoglobinuria. Among its related pathways are Degradation of the extracellular matrix and Cell surface interactions at the vascular wall. An important paralog of this gene is CEACAM6.Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner (PubMed:8776764, PubMed:2022629, PubMed:11590190). Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:8776764, PubMed:2022629, PubMed:11590190). Heterophilic interaction with CEACAM8 occurs in activated neutrophils.

Chromosomal Localization:

19q13.2

Accession Number:

NP_001807.2

UniProt Accession Number:

P31997

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

IIGYVISNQQITPGPAYSNR

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

2200

Last Updated:

12/16/2020

Links

• EnsEMBL - EnsEMBL CEACAM8
• Entrez - Entrez CEACAM8
• Uniprot - Uniprot P31997

Characterization Data

SOPs