[PDF] Cell adhesion and signalling by cadherins and Ig-CAMs in cancer | Semantic Scholar
@article{Cavallaro2004CellAA,
title={Cell adhesion and signalling by cadherins and Ig-CAMs in cancer},
author={Ugo Cavallaro and Gerhard Christofori},
journal={Nature Reviews Cancer},
year={2004},
volume={4},
pages={118-132},
url={https://api.semanticscholar.org/CorpusID:18383054}
}In addition to their adhesive functions, cell-adhesion molecules modulate signal-transduction pathways by interacting with molecules such as receptor tyrosine kinases, components of the WNT signalling pathway and RHO-family GTPases, which have a crucial role in tumour progression.