Pax genes and organogenesis | Semantic Scholar
@article{Dahl1997PaxGA,
title={Pax genes and organogenesis},
author={Edgar Dahl and Haruhiko Koseki and Rudi Balling},
journal={BioEssays},
year={1997},
volume={19},
url={https://api.semanticscholar.org/CorpusID:23755557}
}Pax genes are a family of development control genes that encode nuclear transcription factors. They are characterized by the presence of the paired domain, a conserved amino acid motif with DNA‐binding activity. Originally, paired‐box‐containing genes were detected in Drosophila malenogaster, where they exert multiple functions during embryogenesis. In vertebrates, Pax genes are also involved in embryogenesis. Mutations in four out of nine characterized Pax genes have been associated with…