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The Effects of the Tramadol Metabolite O-Desmethyl Tramadol on Muscarinic Receptor-Induced Responses in Xenopus Oocytes Expressing Cloned M1 or M3 Receptors | Semantic Scholar

@article{Nakamura2005TheEO,
  title={The Effects of the Tramadol Metabolite O-Desmethyl Tramadol on Muscarinic Receptor-Induced Responses in Xenopus Oocytes Expressing Cloned M1 or M3 Receptors},
  author={Motohiro Nakamura and Kouichiro Minami and Yasuhito Uezono and Takafumi Horishita and Jun-ichi Ogata and Munehiro Shiraishi and Takashi Okamoto and Tadanori Terada and Takeyoshi Sata},
  journal={Anesthesia \& Analgesia},
  year={2005},
  volume={101},
  pages={180-186},
  url={https://api.semanticscholar.org/CorpusID:23861688}
}

O-desmethyl tramadol inhibits functions of M1 receptors but has little effect on those of M3 receptors, which may help to explain its neural function.

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