Innovative therapies for systemic sclerosis | Semantic Scholar

Factors that need to be considered in the future include deeper knowledge of the pathogenic mechanisms, the identification of valuable biomarkers assessing efficacy and safety and finally the more defined characterization of optimum treatment paradigms and most appropriate patient populations for the use of new therapeutic agents.

Novel therapies that block key mediators that drive the fibrotic response are being developed and appear as potential therapeutic tools in the treatment of SSc, highlighting the importance for an effective therapy targeted towards the molecular and cellular pathways.