[PDF] High-quality de novo assembly of the apple genome and methylome dynamics of early fruit development | Semantic Scholar

A complete and easy to use pipeline is developped which aim is to handle the complete treatment of WGBS data, from the reads mapping to the DMRs computing, which can handle datasets having a low number of biological replicates.

Comparative analyses indicate that at least a single WGD is shared by both pear and apple, and it has likely occurred following pear/apple lineage split from that of strawberry (Fragaria), supporting the hypothesis that syntenic blocks found in apple (and pear) have been generated by the Malinae WGD.