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Mecamylamine – a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders | Semantic Scholar

@article{Bacher2009MecamylamineA,
  title={Mecamylamine – a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders},
  author={Ingrid Bacher and Becky S. Wu and Douglas Ronald Shytle and Tony P. George},
  journal={Expert Opinion on Pharmacotherapy},
  year={2009},
  volume={10},
  pages={2709 - 2721},
  url={https://api.semanticscholar.org/CorpusID:25690407}
}

Two independent Phase II clinical trials recently confirmed mecamylamine's hypothesized antidepressant activity and suggest that it may be effective as an augmentation pharmacotherapy for SSRI treatment resistant major depression.

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