Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type? | Semantic Scholar
@article{Toyoda2009EarwaxOA, title={Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?}, author={Yu Toyoda and Aki Sakurai and Yasumasa Mitani and Masahiro Nakashima and Koh-ichiro Yoshiura and Hiroshi Nakagawa and Yasuo Sakai and Ikuko Ota and Alexander Lezhava and Yoshihide Hayashizaki and Norio Niikawa and Toshihisa Ishikawa}, journal={The FASEB Journal}, year={2009}, volume={23}, pages={2001 - 2013}, url={https://api.semanticscholar.org/CorpusID:26853548} }
The evidence is provided that this genetic polymorphism has an effect on the Alinked glycosylation of ABCC11, intracellular sorting, and proteasomal degradation of the variant protein.