[PDF] Behavioral and cognitive effects of tyrosine intake in healthy human adults | Semantic Scholar

The present study breaks new ground in relating the impact of a dietary supplement to challenge and threat states and finding that tyrosine may in some cases attenuate the negative effects of a threat state.

A cross-sectional association between habitual tyrosine intake levels in daily nutrition and cognitive performance (WM, Gf, and EM) is extended to corroborates nutritional recommendations that are thus far derived from single-dose administration studies.

Elevated blood concentrations of neurotransmission-related amino acids are associated with improved neuropsychological performance after a single bout of high-intensity exercise and regression analysis indicated that tyrosine accounted for 38.0% of the variance in the Trail Making Test part-A test.

These findings provide first evidence that tyrosine supplementation might impact psychophysiological parameters, and suggest that modeling approaches based on sequential sampling models can yield novel insights into latent cognitive processes modulated by amino-acid supplementation.

These findings provide the first evidence linking tyrosine intake with LC-NA system signal intensity and its correlation with neuropsychological performance and strengthens the role of diet for maintaining brain and cognitive health and supports the noradrenergic theory of cognitive reserve.

The current findings suggest that SAGAT contributes to maintaining proper motivation and cognitive function in the recovery period after mental work loaded in a four-week intervention compared to the placebo.

Tyrosine depletion in healthy volunteers affected baseline dopamine function on the different measures employed in this study, suggesting that this manipulation may be free of significant side effects when used as a treatment for conditions characterised by dopamine over activity, such as acute mania and schizophrenia.

While APTD did not induce relapse in any participant, it did cause patients recovered from depression to show lowered sensitivity to reward in a gambling game, suggesting a specific role for the involvement of DA in reward/punishment processing in humans.

Findings in the present study are consistent with the hypothesis that dopaminergic factors are particularly involved in disrupted affect/reward-based processing characteristic of clinical depression.

This review focuses on Tyr and phenylalanine (Phe).

The results indicate that fatigue during endurance exercise was increased by pharmacological augmentation of the brain serotonergic activity, however, a reduction of 5-HT synthesis via BCAA supplementation did not affect physical fatigue.