semanticscholar.org

[PDF] Dissecting Temporal and Spatial Control of Cytokinesis with a Myosin II Inhibitor | Semantic Scholar

@article{Straight2003DissectingTA,
  title={Dissecting Temporal and Spatial Control of Cytokinesis with a Myosin II Inhibitor},
  author={Aaron F. Straight and Amy Cheung and John Limouze and Irene Chen and Nicholas James Westwood and James R. Sellers and Timothy J. Mitchison},
  journal={Science},
  year={2003},
  volume={299},
  pages={1743 - 1747},
  url={https://api.semanticscholar.org/CorpusID:38625401}
}

It is shown that exit from the cytokinetic phase of the cell cycle depends on ubiquitin-mediated proteolysis and continuous signals from microtubules are required to maintain the position of the cleavage furrow, and these signals control the localization of myosin II independently of other furrow components.

1,397 Citations

29 References

Animal cell cytokinesis.

An overview of the literature on cytokinesis is provided with a particular emphasis on the molecular pathways involved in the division of animal cells.