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ANTIANDROGEN THERAPY IN DERMATOLOGY | Semantic Scholar

Management of Androgenetic Alopecia

There have been tremendous advances in the treatment of hair loss in recent years and the future is very encouraging, as the knowledge of androgenetic alopecia pathophysiology increases, novel targeted treatments will potentially be developed.

Ketoconazole blocks testosterone synthesis.

The diminution of testosterone synthesis could be significant as further therapeutic trials may use larger doses or more than once-daily administration, and the paucity of reports of endocrinologic toxicity may relate to the "escape from the block demonstrated in vivo.