Unexpected dependence of RyR1 splice variant expression in human lower limb muscles on fiber-type composition | Semantic Scholar
@article{Willemse2015UnexpectedDO, title={Unexpected dependence of RyR1 splice variant expression in human lower limb muscles on fiber-type composition}, author={Hermia Willemse and Angelo Theodoratos and Paul N. Smith and Angela F. Dulhunty}, journal={Pfl{\"u}gers Archiv - European Journal of Physiology}, year={2015}, volume={468}, pages={269 - 278}, url={https://api.semanticscholar.org/CorpusID:5894066} }
The results suggest that the reduced expression of ASI(−)RyR1 during development may reflect a reduction in type 1 fibers during development, which may compensate for the reduced terminal cisternae volume, fewer junctional contacts and reduced charge movement in type1 fibers.
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PHYSIOLOGICAL CONSEQUENCES AND CLINICAL IMPLICATIONS OF THE CHANGES IN COMPONENTS OF THE RYR 1 COMPLEX
- 2016