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Somatic point mutations occurring early in development: a monozygotic twin study | Semantic Scholar

@article{Li2013SomaticPM,
  title={Somatic point mutations occurring early in development: a monozygotic twin study},
  author={Rui Li and Alexandre Montpetit and Maryl{\`e}ne Rousseau and Si-Yu Wu and Celia M. T. Greenwood and Tim D. Spector and Michael N. Pollak and Constantin Polychronakos and J. Brent Richards},
  journal={Journal of Medical Genetics},
  year={2013},
  volume={51},
  pages={28 - 34},
  url={https://api.semanticscholar.org/CorpusID:6031153}
}

Findings provide direct evidence that early somatic point mutations do occur and can lead to differences in genomes between otherwise identical twins, suggesting a considerable burden of somatic mutations among the trillions of mitoses that occur over the human lifespan.

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