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Crystal structure and assembly of a eukaryotic small heat shock protein | Semantic Scholar

@article{Montfort2001CrystalSA,
  title={Crystal structure and assembly of a eukaryotic small heat shock protein},
  author={Rob L. M. van Montfort and Eman Basha and Kenneth L. Friedrich and Christine Slingsby and Elizabeth Vierling},
  journal={Nature Structural Biology},
  year={2001},
  volume={8},
  pages={1025-1030},
  url={https://api.semanticscholar.org/CorpusID:618916}
}

The 2.7 Å structure of wheat HSP16.9, a member of the small heat shock proteins (sHSPs), indicates how its α-crystallin domain and flanking extensions assemble into a dodecameric double disk, and provides a model by which members of the sHSP protein family bind unfolded substrates.

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Subunit Exchange of Small Heat Shock Proteins

The development of a fluorescence resonance energy transfer method for measuring structural compatibility between αA-crystallin and other proteins is reported, suggesting residues 20–56 are essential for the formation of large oligomers and the exchange of subunits in a dynamic equilibrium with the oligomeric complex.