Controlled Release Drugs in Overdose | Semantic Scholar

In both patients, the tablets were visualized on abdominal radiographs and the gastrointestinal tracts of both were successfully decontaminated using whole-bowel irrigation, and the abdominal radiograph appears to be useful in detecting sustained-release potassium tablets.

A prospective evaluation of patients 12 years or older who were referred to the Massachusetts Poison Control System because of theophylline intoxication found that patients who are chronically overmedicated have a greater risk for life-threatening manifestations, with major toxicity occurring when serum theophylla concentrations are in what is considered the range for mild toxicity.