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@article{Doney2010TheGH,
  title={The Growing Human Footprint on Coastal and Open-Ocean Biogeochemistry},
  author={Scott C. Doney},
  journal={Science},
  year={2010},
  volume={328},
  pages={1512 - 1516},
  url={https://api.semanticscholar.org/CorpusID:8792396}
}

Major observed trends include a shift in the acid-base chemistry of seawater, reduced subsurface oxygen both in near-shore coastal water and in the open ocean, rising coastal nitrogen levels, and widespread increase in mercury and persistent organic pollutants.

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Spreading Dead Zones and Consequences for Marine Ecosystems

Dead zones in the coastal oceans have spread exponentially since the 1960s and have serious consequences for ecosystem functioning, exacerbated by the increase in primary production and consequent worldwide coastal eutrophication fueled by riverine runoff of fertilizers and the burning of fossil fuels.