BIGSdb: Scalable analysis of bacterial genome variation at the population level - BMC Bioinformatics

The Genome Comparator plugin can identify loci shared among genomes. ClonalFrame trees were generated from 43 Streptococcal genome sequences using A) seven MLSA gene fragment loci and B) 77 complete genes found to be present throughout the genus identified by BIGSDB. Aligned sequences were exported from the database and 50% consensus trees generated from six independent runs with 50 k iterations, 50 k burn-in iterations, and a thinning interval of 100.

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