link.springer.com

Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast - Current Genetics

  • ️Hohmann, S.
  • ️Mon Jan 01 1990

Summary

suc2° is a naturally occurring amber mutant allele of the yeast invertase structural gene SUC2. Strains carrying suc2° had only 10% of the wild type invertase-specific mRNA level. Amber suppressors, which allowed suc2° strains to ferment sucrose caused an increase of the SUC-specific mRNA level.

Access this article

Log in via an institution

Subscribe and save

  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Baserga SJ, Benz EJ (1988) Proc Natl Acad Sci USA 85:2056–2060

    Google Scholar 

  • Beggs JD (1978) Nature 275:447–452

    Google Scholar 

  • Bossi L, Roth JR (1980) Nature 286:123–127

    Google Scholar 

  • Brown AJP, Purvis IJ, Santiago TC, Bettany AJE, Loughlin L, Moore J (1988) Gene 72:151–160

    Google Scholar 

  • Carlson M, Osmond BC, Botstein D (1981) Genetics 98:41–54

    Google Scholar 

  • Cleveland DW (1988) Trends Biochem Sci 13:339–343

    Google Scholar 

  • Feinstein SI, Altman S (1978) Genetics 88:201–219

    Google Scholar 

  • Gallwitz D, Sures J (1980) Proc Natl Acad Sci USA 77:2546–2550

    Google Scholar 

  • Gozalbo D, Hohmann S (1989) Mol Gen Genet 216:511–516

    Google Scholar 

  • Hohmann S (1987) PhD Thesis, Technische Hochschule Darmstadt

  • Kohli J, Grosjean H (1981) Mol Gen Genet 182:430–439

    Google Scholar 

  • Losson L, Lacroute F (1979) Proc Natl Acad Sci USA 76:5134–5137

    Google Scholar 

  • Pelsey F, Lacroute F (1984) Curr Genet 8:277–282

    Google Scholar 

  • Purvis IJ, Bettany AJE, Loughlin L, Brown AJP (1987) Nucleic Acids Res 15:7951–7962

    Google Scholar 

  • Ross J, Peltz SW, Kobs G, Brewer G (1987) J Biol Chem 262:9374–9381

    Google Scholar 

  • Santiago TC, Bettany AJE, Purvis IJ, Brown AJP (1987) Nucleic Acids Res 15:2417–2429

    Google Scholar 

  • Schneider E, Blundell M, Kennel D (1978) Mol Gen Genet 160:121–129

    Google Scholar 

  • Sherman F (1982) In: Strathern JN, Jones EW, Hicks JB (eds) Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

  • Struhl K, Stinchcomb DT, Scherer S, Davis RW (1979) Proc Natl Acad Sci USA 76:1035–1039

    Google Scholar 

  • Yen TJ, Gay DA, Pachter JS, Cleveland DW (1988) Mol Cell Biol 8:1224–1235

    Google Scholar 

Download references

Author information

Author notes

  1. D. Gozalbo

    Present address: Departament de Microbiologia, Facultat de Farmacia, Universitat de Valencia, Avgda Blasco Ibanez 13, E-46010, Valencia, Spain

Authors and Affiliations

  1. Institut für Mikrobiologie, Technische Hochschule Darmstadt, Schnittspahnstrasse 10, D-6100, Darmstadt, Germany

    D. Gozalbo & S. Hohmann

Authors

  1. D. Gozalbo

    You can also search for this author in PubMed Google Scholar

  2. S. Hohmann

    You can also search for this author in PubMed Google Scholar

Additional information

Communicated by K. Wolf

About this article

Cite this article

Gozalbo, D., Hohmann, S. Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast. Curr Genet 17, 77–79 (1990). https://doi.org/10.1007/BF00313252

Download citation

  • Received: 14 October 1989

  • Issue Date: January 1990

  • DOI: https://doi.org/10.1007/BF00313252

Key words