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Action of cannabidiol on the anxiety and other effects produced by δ9-THC in normal subjects - Psychopharmacology

  • ️Karniol, I. G.
  • ️Mon Mar 01 1982
  • Agurell S, Levander S, Bindler M, Bader-Bartfai A, Gustafson B, Leander K, Lindgren J, Ohlsson A, Tobisson B (1976) Pharmacokinetics of Δ 8-tetrahydrocannabinol (Δ 6-tetrahydrocannabinol) in man after smoking — Relations to physiological and psychological effects. In: Braude MC, Szara S (eds) The pharmacology of marihuana. Raven Press, New York, pp 49–61

    Google Scholar 

  • Bech P, Rafaelsen L, Rafaelsen OJ (1974) Cannabis: A psychopharmacological review. Dan Med Bull 21 (3):106–120

    Google Scholar 

  • Biaggio AMB, Natalício L, Spielberger CD (1977) Desenvolvimento da forma experimental em portugues do Inventário de Ansiedade. Traço — Estado (IDATE), de Spielberger. Arquivos Brasileiros de Psicologia Aplicada 29:31–44

    Google Scholar 

  • Bond A, Lader M (1974) The use of analogue scales in rating subjective feelings. Br J Med Psychol 47:211–218

    Google Scholar 

  • Borg J, Gerson S, Alpert M (1975) Dose effects of smoked marihuana on human cognitive and motor functions. Psychopharmacologia 42:211–218

    Google Scholar 

  • Bussab WO (1976) Hierarchical dichotomous partitions in cluster analysis. PhD Thesis, University of London

  • Cappell H, Kuchar E (1974) Pharmacologic and nonpharmacologic factors in marijuana intoxication. Clin Toxicol 7:315

    Google Scholar 

  • Carlin AS, Bakker CB, Halpern L, Post RD (1972) Social facilitation of marijuana intoxication: Impact of social set and pharmacological activity. J Abnorm Psychol 80:132–140

    Google Scholar 

  • Carlini EA, Leite JR, Tanhauser M, Berardi AC (1973) Cannabidiol and Cannabis sativa extract protect mice and rats against convulsive agents. J Pharm Pharmacol 25:664–665

    Google Scholar 

  • Carlini EA, Masur J, Magalhães CCPB (1979) Possível efeito hipnótico do canabidiol no ser humano. Estudo preliminar. Cìência e Cultura 31:315–322

    Google Scholar 

  • Cunha JM (1979) O efeito anti-epiléptico do canabidiol. Tese de doutoramento apresentada a Escola Paulista de Medicina, São Paulo

  • Dalton WS, Martz R, Lemberger L, Rodda BE, Forney B (1976) Influence of cannabidiol on Δ 9-tetrahydrocannabinol effects. Clin Pharmacol Ther 19:300–309

    Google Scholar 

  • Davis WM, Borgen LA (1974) Effects of cannabidiol and Δ 9-tetrahydrocannabinol on operant behavior. Res Commun Chem Pathol Pharmacol 9:453–462

    Google Scholar 

  • Fernandes M, Schabarek A, Coper H, Hill R (1974) Modification of Δ 9-THC actions by cannabinol and cannabidiol in the rat. Psychopharmacologia 38:329–338

    Google Scholar 

  • Galanter M, Wyatt RJ, Lemberger L, Weingartner H, Vaughan TB, Roth WT (1972) Effects on humans of Δ 9-tetrahydrocannabinol administered by smoking. Science 176:934–936

    Google Scholar 

  • Gregg JM, Small EW, Moore R, Raft D, Toomey TC (1976) Emotional response to intravenous Δ 9-tetrahydrocannabinol during oral surgery. J Oral Surg 34:301–313

    Google Scholar 

  • Grlic L (1976) A comparative study on some chemical and biological characteristics of various samples of cannabis resin. Bull Narcot 14:37–46

    Google Scholar 

  • Haertzen CA, Hill HE, Belleville RE (1963) Development of the Addiction Research Center Inventory (ARCI): Selection of items that are sensitive to the effects of various drugs. Psychopharmacologia 4:155–166

    Google Scholar 

  • Hollister LE (1971) Manhuana in man: three yeas later. Science 172:21–29

    Google Scholar 

  • Hollister LE (1973) Cannabidiol and cannabinol in man. Experientia 29:825–826

    Google Scholar 

  • Hollister LE, Gillespie H (1975) Interactions in man of Δ 9-tetrahydrocannabinol. II-Cannabinol and Cannabidiol. Clin Pharmacol Ther 18:80–83

    Google Scholar 

  • Hollister LE, Richards RK, Gillespie H (1968) Comparison of tetrahydrocannabinol and synhexil in human. Clin Pharmacol Ther 9 (6):783–791

    Google Scholar 

  • Isbell H, Jasinski DR (1969) A comparison of LSD-25 with (-)Δ 9-tetrahydrocannabinol (THC) and attempted cross tolerance between LSD and THC. Psychopharmacologia 14:115–123

    Google Scholar 

  • Jones RT (1971) Tetrahydrocannabinol and the marijuana — Induced social “high”, or the effects of the mind on marijuana. In: Singer AD (ed) Marijuana. Chemistry, Pharmacology, and Patterns of Social Use. New York Academy of Sciences, pp 155–165

  • Jones RT (1978) Marihuana: Human effects. In: Iversen LL, Iversen SD, Snyder SH (eds) Handbook of Psychopharmacology. Drugs of Abuse. Plenum Press, New York, pp 373–412

    Google Scholar 

  • Karniol IG, Carlini EA (1973) Comparative studies in man and in laboratory animals on Δ 8- and Δ 9-trans-tetrahydrocannabinol. Pharmacology 9:115–126

    Google Scholar 

  • Karniol IG, Dalton J, Lader M (1976) Comparative psychotropic effects of trazodone imipramine and diazepam in normal subjects. Curr Ther Res 20 (3):337–347

    Google Scholar 

  • Karniol IG, Dalton J, Lader M (1978) Acute and chronic effects of lithium chloride on physiological and psychological measures in normals. Psychopharmacology 57:289–294

    Google Scholar 

  • Karniol IG, Shirakawa I, Kasinski N, Pfeferman A, Carlini EA (1974) Cannabidiol interferes with the effects of Δ 9-tetrahydrocannabinol in man. Eur J Pharmacol 28:172–177

    Google Scholar 

  • Kiplinger GF, Manno JE, Rodda BE, Forney RB (1971) Dose-response analysis of the tetrahydrocannabinols in man. Clin Pharmacol Ther 12:650–657

    Google Scholar 

  • Klapper JA, McCulloch MA, Sidell RF (1972) The effect on personality of reactivity to 1,2-dimethyl-heptyl tetrahydrocannabinol. Arch Gen Psychiatry 26:483–485

    Google Scholar 

  • Malit LA, Johnstone RF, Bourke DI, Kulp RA, Klein D, Eng D, Smith DC (1975) Intravenous Δ 9-tetrahydrocannabinol: effects on ventilatory control and cardiovascular dynamics. Anesthesiol 42:666–673

    Google Scholar 

  • Martz R, Brown DJ, Forney RB, Bright TP, Kiplinger GF, Rodda BE (1972) Propanolol antagonism of marihuana induced tachycardia. Life Sci 11:999–1005

    Google Scholar 

  • Meyer RE (1978) Behavioral pharmacology of marihuana. In: Lipton MA, Dimascio A, Killam KF (eds) Psychopharmacology: A generation of progress. Raven Press, New York, pp 1634–1652

    Google Scholar 

  • Miller LL, Cornett TL (1978) Marijuana: dose effects on pulse rate, subjective estimates of intoxication free recall and recognition memory. Pharmacol Biochem Behav 9:573–577

    Google Scholar 

  • Monti JM (1977) Hypnoticlike effects of cannabidiol in the rat. Psychopharmacology 55:263–265

    Google Scholar 

  • Naliboff BD, Rickles WH, Cohen MJ, Naimark RS (1976) Interactions of marijuana and induced stress: forearm blood flow heart rate, and skin conductance. Psychophysiology 13:517–522

    Google Scholar 

  • Norris H (1971) The action of sedatives on brain stem oculomotor systems in man. Neuropharmacology 10:181–191

    Google Scholar 

  • Perez-Reyes M, Timmons MC, Dauls KH, Wall ME (1973) A comparison of the pharmacological activity in man of the intravenously administered Δ 9-tetrahydrocannabinol, cannabinol and cannabidiol. Experientia 29:1368–1369

    Google Scholar 

  • Pillard RC, McNair DM, Fisher S (1974) Does marijuana enhance experimental induced anxiety? Psychopharmacologia 40:205–210

    Google Scholar 

  • Rossi AM, Kuehnle JC, Mendelson JH (1978) Marihuana and mood in human volunteers. Pharmacol Biochem Behav 8:447–455

    Google Scholar 

  • Scott AJ, Knott M (1974) A cluster analysis method for grouping means in the analysis of variance. Biometrics 30:507–512

    Google Scholar 

  • Siegel S (1956) Nonparametric statistics for the behavioral sciences. McGraw-Hill e Kogakusha, Ltd., Japan

    Google Scholar 

  • Spielberger CD, Gorsuch RL, Lushene RE (1970) Manual for the State-Trait Anxiety Inventory. Consulting Psychologist Press, Palo Alto, CA

    Google Scholar 

  • Szara S (1976) Clinical pharmacology of cannabis: scientific and nonscientific constrainst. In: Braude MC, Szara S (eds) The pharmacology of marihuana. Raven Press, New York, pp 22–33

    Google Scholar 

  • Tassinari CA, Ambrosetto G, Peraita-Adrados MR, Gestaut H (1976) The neuropsychiatric syndrome of Δ 9-tetrahydrocannabinol and cannabis intoxication in naive subjects: a clinical and poligraphic study during wakefulness and sleep. In: Braude MC, Szara S (eds) The pharmacology of marihuana. Raven Press, New York

    Google Scholar 

  • Weil AT, Zinberg NE, Nelsen JM (1968) Clinical and psychological effects of marihuana in man. Science 162:1234–1242

    Google Scholar 

  • Zuardi AW, Karniol IG (1981) Estudo transcultural de uma escala de auto-avaliação para estados subjectivos. J Brasileiro de Psiquiatria (in press)