Resistance training reduces pain indices and improves quality of life and body strength in women with migraine disorders - Sport Sciences for Health

Purpose

The benefits of resistance training (RT) for migraineurs appears to be lacking although beneficial of aerobic training have been shown in previous studies. The aim of the current study, therefore, is to investigate the influence of RT on migraine headache indices, upper and lower-body strength, and quality of life (QOL) in women with migraine disorders.

Methods

Twenty female migraine patients who were referred by a neurologist were randomly assigned to two groups including RT group (n = 10) and control (CON) group (n = 10). The RT protocol consisted of 8 weeks, 3 sessions per week, 45–60 min per session. Visual Analog Scale (VAS) and pain diary were utilized to measure the subjects’ migraine indices including duration, pain severity, and frequency within 48 h pre- and post-training protocol. Patients in the Control group (CON) have been refrained from regular exercise during this study. The quality of life (QOL) and muscular strength were measured by the Headache Impact Tests (HIT) and one-repetition maximum (1RM) test, respectively, for 48 h pre- and post-training protocol.

Results

The RT resulted in a significant decrease in the migraine indices (headache intensity, frequency, and duration) (p = 0.02, p = 0.001, p = 0.04, respectivetly). Increased quality of life and chest and leg muscular strength significantly (p = 0.001 for all) were also showed after 8-week RT protocol. However, there were not any significant differences between groups considering, BMI and waist-hip ratio (WHR) after executing RT protocol (p > 0.05).

Conclusion

Based on the results of the current study that mainly had a positive trend, it could state that RT protocol with special consideration for migraine patients is probably an alternative therapy or augmentative complement to established interventions for migraine treatment.

1RM:

One-repetition maximum

BMI:

Body mass index

CGRP:

Calcitonin gene-related peptide

CSD:

Cortical spreading depression

DUR:

Duration

FRQ:

Frequency

HIT:

Headache impact tests

ICHD:

International classification of headache disorders

IHS:

International headache society

INT:

Intensity

QOL:

Quality of life

RT:

Resistance training

SED:

Sedentary

VAS:

Visual Analog Scale

WHR:

Waist to hip ratio

1. Durstine JL, Painter P, Franklin BA, Morgan D, Pitetti KH, Roberts SO (2000) Physical activity for the chronically Ill and disabled. Sports Med 30(3):207–219

   Article  CAS  Google Scholar 

2. Varkey E, Grüner Sveälv B, Edin F, Ravn-Fischer A, Cider Å (2017) Provocation of migraine after maximal exercise: a test-retest study. Eur Neurol 78(1–2):22–27

   Article  Google Scholar 

3. Varkey E, Cider A, Carlsson J, Linde M (2009) A Study to evaluate the feasibility of an aerobic exercise program in patients with migraine. Headache 49(4):563–570

   Article  Google Scholar 

4. Pairo Z, Parnow A, Sari-aslani P, Eslami R (2016) Effect of moderate intensity aerobic exercise on migraine headache indexes and quality of life improvement in women with migraine. Q Horiz Med Sci 22:291–297

   Article  Google Scholar 

5. Busch V, Gaul C (2008) Exercise in migraine therapy—is there any evidence for efficacy? A critical review. Headache 48(6):890–899

   Article  Google Scholar 

6. Eftekhari S, Edvinsson L (2010) Possible sites of action of the new calcitonin gene-related peptide receptor antagonists. Ther Adv Neurol Disord 3(6):369–378

   Article  CAS  Google Scholar 

7. Varkey E (2012) On the prevention of migraine-focus on exercise and the patient’s perspective. University of Gothenburg, Gothenburg

   Google Scholar 

8. Hindiyeh NA, Krusz JC, Cowan RP (2013) Does exercise make migraines worse and tension type headaches better? Curr Pain Headache Rep. https://doi.org/10.1007/s11916-013-0380-5

   Article  PubMed  Google Scholar 

9. Schwartz JS, Song P, Blitzer A (2007) Headache. Therapeutic uses of botulinum toxin. Humana Press, pp 91–108

   Book  Google Scholar 

10. Gil-Martínez A, Kindelan-Calvo P, Agudo-Carmona D, Muñoz-Plata R, López-de-Uralde-Villanueva I, La Touche R (2013) Therapeutic exercise as treatment for migraine and tension-type headaches: a systematic review of randomised clinical trials. Rev Neurol 57(10):433–443

    PubMed  Google Scholar 

11. Totzeck A, Unverzagt S, Bak M, Augst P, Diener HC, Gaul C (2012) Aerobic endurance training versus relaxation training in patients with migraine (ARMIG): study protocol for a randomized controlled trial. Trials. https://doi.org/10.1186/1745-6215-13-46

    Article  PubMed  PubMed Central  Google Scholar 

12. Eslami R, Parnow A, Pairo Z, Nikolaidis P, Knechtle B (2021) The effects of two different intensities of aerobic training protocols on pain and serum neuro-biomarkers in women migraineurs: a randomized controlled trail. Eur J Appl Physiol 121(2):609–620

    Article  Google Scholar 

13. Barber M, Pace A (2020) Exercise and migraine prevention: a review of the literature. Curr Pain Headache Rep 24(8):1–7

    Article  Google Scholar 

14. Parnow AH, Gharakhanlou R, Eslami R (2012) Effects of physical activity on calcitonin gene-related peptide content at trigeminal ganglion nerve in wistar rats. J Mazandaran Univ Med Sci 22(90):25–31

    Google Scholar 

15. La Touche R, Fernández Pérez JJ, Proy Acosta A, González Campodónico L, Martínez García S, Adraos Juárez D et al (2020) Is aerobic exercise helpful in patients with migraine? A systematic review and meta-analysis. Scand J Med Sci Sports 30(6):965–982

    Article  Google Scholar 

16. Song T-J, Chu MK (2021) Exercise in treatment of migraine including chronic migraine. Curr Pain Headache Rep 25(3):1–11

    Article  Google Scholar 

17. Faul F, Erdfelder E, Lang A-G, Buchner A (2007) G* Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39(2):175–191

    Article  Google Scholar 

18. Marchese R, Taylor J, Fagan K (2019) The essential guide to fitness: for the fitness instructor. Cengage Learning, Australia

    Google Scholar 

19. Brzycki M (1989) A practical approach to strength training. Masters Press, Grand Rapids, MI

    Google Scholar 

20. Yang M, Rendas-Baum R, Varon SF, Kosinski M (2011) Validation of the Headache Impact Test (HIT-6^TM) across episodic and chronic migraine. Cephalalgia 31(3):357–367

    Article  Google Scholar 

21. De Wilde JA, Van Dommelen P, Middelkoop BJC (2013) Appropriate body mass index cut-offs to determine thinness, overweight and obesity in South Asian children in The Netherlands. PLoS ONE 8(12):e82822

    Article  Google Scholar 

22. Amin FM, Aristeidou S, Baraldi C, Czapinska-Ciepiela EK, Ariadni DD, Di Lenola D et al (2018) The association between migraine and physical exercise. J Headache Pain 19(1):83

    Article  Google Scholar 

23. Misra UK, Kalita J, Tripathi GM, Bhoi SK (2013) Is β endorphin related to migraine headache and its relief? Cephalalgia 33(5):316–322

    Article  Google Scholar 

24. Köseoglu E, Akboyraz A, Soyuer A, Ersoy AÖ (2003) Aerobic exercise and plasma beta endorphin levels in patients with migrainous headache without aura. Cephalalgia 23(10):972–976

    Article  Google Scholar 

25. Krøll LS, Hammarlund CS, Linde M, Gard G, Jensen RH (2018) The effects of aerobic exercise for persons with migraine and co-existing tension-type headache and neck pain. A randomized, controlled, clinical trial. Cephalalgia 38(12):1805–1816

    Article  Google Scholar 

26. Darabaneanu S, Overath CH, Rubin D, Lüthje S, Sye W, Niederberger U et al (2011) Aerobic exercise as a therapy option for migraine: a pilot study. Int J Sports Med 32(6):455–460

    Article  CAS  Google Scholar 

27. Jackson W, Zale EL, Berman SJ, Malacarne A, Lapidow A, Schatman ME et al (2019) Physical functioning and mindfulness skills training in chronic pain: a systematic review. J Pain Res 12:179–189

    Article  Google Scholar 

28. Daenen L, Varkey E, Kellmann M, Nijs J (2015) Exercise, not to exercise, or how to exercise in patients with chronic pain? Applying science to practice. Clin J Pain 31(2):108–114

    Article  Google Scholar 

29. Irby MB, Bond DS, Lipton RB, Nicklas B, Houle TT, Penzien DB (2016) Aerobic exercise for reducing migraine burden: mechanisms, markers, and models of change processes. Headache 56(2):357–369

    Article  Google Scholar 

30. Bigal M, Krymchantowski AV, Lipton RB (2009) Barriers to satisfactory migraine outcomes. What have we learned, where do we stand?: Views and perspectives. Headache 49(7):1028–1041

    Article  Google Scholar 

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Authors and Affiliations

1. Neurology Department, School of Medicine, Medical Sciences of Kermanshah University, Kermanshah, Iran

   Payam Sari Aslani

2. Exercise Physiology Department, Sports Sciences Faculty, Razi University, PO BOX 6714414874, Kermanshah, Iran

   Maryam Hassanpour, Omid Razi & Abdolhossein Parnow

3. Institute of Primary Care, University of Zurich, Zurich, Switzerland

   Beat Knechtle

4. Medbase St. Gallen Am Vadianplatz, St. Gallen, Switzerland

   Beat Knechtle

Contributions

AP contributed to designing research and final edition, MA contributed to the literature search, training the subjects, and data collection. OR contributed in preparing the manuscript, BK contributed in discussion preparation, and, PS contributed as supervisor and Neurologist to Migraine patients.

Corresponding author

Correspondence to Abdolhossein Parnow.

Conflict of interest

All authors declare no conflicts of interest.

Ethical approval

The Medical Ethics Committee formally approved this research, Medical Sciences University, Kermanshah, Iran (ethical code: IR.kums.rec.1394.15), and it was registered at the Iranian Registry of Clinical Trials (IRCT2015100910824N2).

Consent to participate

All patients were requested to fill out the consent form.

Consent for publication

All authors are consent to publish the manuscript.

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