link.springer.com

Reduced Cerebellar Inhibition in Migraine with Aura: A TMS Study - The Cerebellum

  • ️Fierro, Brigida
  • ️Wed Jan 21 2009
  • Pietrobon D (2005) Migraine: new molecular mechanisms. Neuroscientist 11:373–386

    Article  PubMed  CAS  Google Scholar 

  • Ophoff RA, Terwindt GM, Vergouwe MN et al (1996) Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+channel gene CACNL1A4. Cell 87:543–552

    Article  PubMed  CAS  Google Scholar 

  • De Fusco M, Marconi R, Silvestri L, Atorino L, Rampoldi L, Morgante L et al (2003) Haploinsufficiency of ATP1A2 encoding the Na+/K+pump alpha2 subunit associated with familial hemiplegic migraine type 2. Nat Genet 33:192–196

    Article  PubMed  Google Scholar 

  • Dichgans M, Freilinger T, Eckstein G, Babini E, Lorenz-Depiereux B, Biskup S et al (2005) Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. Lancet 5(366):371–377

    Article  Google Scholar 

  • Ferrari MD, Haan J (2002) The genetics of migraine: implication for treatment approaches. J Neural Transm Suppl 63:111–127

    PubMed  CAS  Google Scholar 

  • Pietrobon D (2007) Familial Hemiplegic migraine. Neurotherapeutics 4:274–284

    Article  PubMed  CAS  Google Scholar 

  • Bolay H, Reuter U, Dunn AK, Huang Z, Boas DA, Moskowitz MA (2002) Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model. Nat Med 8(136):142

    Google Scholar 

  • Ambrosini A, Maertens de Noordhout A, Schoenen J (2001) Neuromuscular transmission in migraine: a single-fiber EMG study in clinical subgroups. Neurology 56:1038–1043

    PubMed  CAS  Google Scholar 

  • Plomp JJ, Vergouwe MN, Van den Maagdenberg AM, Ferrari MD, Frants RR, Molenaar PC (2000) Abnormal transmitter release at neuromuscular junctions of mice carrying the tottering alpha (1A) Ca (21) channel mutation. Brain 123:463–471

    Article  PubMed  Google Scholar 

  • Craig PJ, McAinsh AD, McCormack AL, Smith W, Beattie RE, Priestley JV (1998) Distribution of the voltage-dependent calcium channel alpha(1A) subunit throughout the mature rat brain and its relationship to neurotransmitter pathways. J Comp Neurol 397:251–267

    Article  PubMed  CAS  Google Scholar 

  • Terwindt GM, Ophoff RA, Haan J, Frants RR, Ferrari MD (1996) Familial hemiplegic migraine: a clinical comparison of families linked and unlinked to chromosome 19. Cephalalgia 16:153–155

    Article  PubMed  CAS  Google Scholar 

  • Sandor PS, Mascia A, Seidel L, de Pasqua V, Schoenen J (2001) Subclinical cerebellar impairment in the common types of migraine: a three-dimensional analysis of reaching movements. Ann Neurol 49:668–672

    Article  PubMed  CAS  Google Scholar 

  • Brighina F, Piazza A, Daniele O, Fierro B (2002) Modulation of visual cortical excitability in migraine with aura: effects of 1 Hz repetitive transcranial magnetic stimulation. Exp Brain Res 145:177–181

    Article  PubMed  Google Scholar 

  • Brighina F, Giglia G, Scalia S, Francolini M, Palermo A, Fierro B (2005) Facilitatory effects of 1 Hz rTMS in motor cortex of patients affected by migraine with aura. Exp Brain Res 161:34–38

    Article  PubMed  Google Scholar 

  • Siniatchkin M, Kroner-Herwig B, Kocabiyik E, Rothenberger A (2007) Intracortical inhibition and facilitation in migraine–a transcranial magnetic stimulation study. Headache 47:364–370

    PubMed  Google Scholar 

  • Dow RS (1974) Some novel concepts of cerebellar physiology. Mt Sinai J Med 41:103–119

    PubMed  CAS  Google Scholar 

  • Ugawa Y, Uesaka Y, Terao Y, Hanajima R, Kanazawa I (1995) Magnetic stimulation over the cerebellum in humans. Ann Neurol 37:703–713

    Article  PubMed  CAS  Google Scholar 

  • Pinto AD, Chen R (2001) Suppression of the motor cortex by magnetic stimulation of the cerebellum. Exp Brain Res 140:505–510

    Article  PubMed  CAS  Google Scholar 

  • Daskalakis ZJ, Paradiso GO, Christensen BK, Fitzgerald PB, Gunraj C, Chen R (2004) Exploring the connectivity between the cerebellum and motor cortex in humans. J Physiol 557:689–700

    Article  PubMed  CAS  Google Scholar 

  • Daskalakis ZJ, Christensen BK, Fitzgerald PB, Fountain SI, Chen R (2005) Reduced cerebellar inhibition in schizophrenia: a preliminary study. Am J Psychiatry 162:1203–1205

    Article  PubMed  Google Scholar 

  • Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9:97–113

    Article  PubMed  CAS  Google Scholar 

  • Headache Classification Subcommittee of the International Headache Society (2004) The International Classification of Headache Disorders: 2nd edn. Cephalalgia 24(Suppl.1):9–160

    Google Scholar 

  • 41st World Medical Assembly (1990) Declaration of Helsinki: Recommendations guiding physicians in biomedical research, involving human subjects. Bull Pan Am Health Organ 24:606–609

    Google Scholar 

  • Kaneko K, Kawai S, Fuchigami Y, Morita H, Ofuji A (1996) The effect of current direction induced by transcranial magnetic stimulation on the corticospinal excitability in human brain. Electroencephalogr Clin Neurophysiol 101:478–482

    Article  PubMed  CAS  Google Scholar 

  • Rothwell JC (1996) The use of paired pulse stimulation to investigate the intrinsic circuitry of human motor cortex. In: Nilsson J, Panizza M, Grandori F (eds) Advances in magnetic stimulation. Mathematical modeling and clinical applications. PI-ME, Pavia, pp 99–104

    Google Scholar 

  • Brighina F, Daniele O, Piazza A, Giglia G, Fierro B (2006) Hemispheric cerebellar rTMS to treat drug-resistant epilepsy: case reports. Neurosci Lett 397:229–233

    Article  PubMed  CAS  Google Scholar 

  • Ugawa Y, Genba-Shimizu K, Rothwell JC, Iwata M, Kanazawa I (1994) Suppression of motor cortical excitability by electrical stimulation over the cerebellum in ataxia. Ann Neurol 36(1):90–96

    Article  PubMed  CAS  Google Scholar 

  • Mulleners WM, Chronicle EP, Palmer JE, Koehler PJ, Vredeveld JW (2001) Visual cortex excitability in migraine with and without aura. Headache 41:565–572

    Article  PubMed  CAS  Google Scholar 

  • Fierro B, Ricci R, Piazza A, Scalia S, Giglia G, Vitello G, Brighina F (2003) 1 Hz rTMS enhances extrastriate cortex activity in migraine: evidence of a reduced inhibition? Neurology 61:1446–1448

    PubMed  CAS  Google Scholar 

  • Aurora SK, al-Sayeed F, Welch KM (1999) The cortical silent period is shortened in migraine with aura. Cephalalgia 19:708–712

    Article  PubMed  CAS  Google Scholar 

  • Bramanti P, Grugno R, Vitetta A, Di Bella P, Muscara N, Nappi G (2005) Migraine with and without aura: electrophysiological and functional neuroimaging evidence. Funct Neurol 20:29–32

    PubMed  Google Scholar 

  • Currà A, Pierelli F, Coppola G, Barbanti P, Buzzi MG, Galeotti F et al (2007) Shortened cortical silent period in facial muscles of patients with migraine. Pain 132:124–131

    Article  PubMed  Google Scholar 

  • Van den Maagdenberg AM, Pietrobon D, Pizzorusso T, Kaja S, Broos LA, Cesetti T et al (2004) A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression. Neuron 41(5):701–710, Mar 4

    Article  PubMed  Google Scholar 

  • Kruit MC, van Buchem MA, Hofman PA, Bakkers JT, Terwindt GM, Ferrari MD, Launer LJ (2004) Migraine as a risk factor for subclinical brain lesions. JAMA 291:427–434

    Article  PubMed  CAS  Google Scholar 

  • Kruit MC, Launer LJ, Ferrari MD, van Buchem MA (2005) Infarcts in the posterior circulation territory in migraine. The population-based MRI CAMERA study. Brain 128:2068–2077

    Article  PubMed  Google Scholar 

  • Kruit MC, Launer LJ, Ferrari MD, van Buchem MA (2006) Brain stem and cerebellar hyperintense lesions in migraine. Stroke 37:1109–1112

    Article  PubMed  Google Scholar 

  • Gerschlager W, Christensen LO, Bestmann S, Rothwell JC (2002) rTMS over the cerebellum can increase corticospinal excitability through a spinal mechanism involving activation of peripheral nerve fibres. Clin Neurophysiol 113:1435–440

    Article  PubMed  CAS  Google Scholar 

  • Werhahn KJ, Taylor J, Ridding M, Meyer BU, Rothwell JC (1996) Effect of transcranial magnetic stimulation over the cerebellum on the excitability of human motor cortex. Electroencephalogr Clin Neurophysiol 101:58–66

    Article  PubMed  CAS  Google Scholar