Cognitive functioning in obsessive-compulsive disorder: a meta-analysis | Psychological Medicine | Cambridge Core

Abbruzzese, M, Bellodi, L, Ferri, S, Scarone, S (1995). Frontal lobe dysfunction in schizophrenia and obsessive–compulsive disorder: a neuropsychological study. Brain and Cognition 27, 202–212.Google Scholar

Abbruzzese, M, Ferri, S, Scarone, S (1997). The selective breakdown of frontal functions in patients with obsessive–compulsive disorder and in patients with schizophrenia: a double dissociation experimental finding. Neuropsychologia 35, 907–912.CrossRefGoogle ScholarPubMed

Abramovitch, A, Dar, R, Schweiger, A, Hermesh, H (2011). Neuropsychological impairments and their association with obsessive–compulsive symptom severity in obsessive–compulsive disorder. Archives of Clinical Neuropsychology 26, 364–376.Google Scholar

Aigner, M, Sachs, G, Bruckmuller, E, Winklbaur, B, Zitterl, W, Kryspin-Exner, I, Gur, R, Katschnig, H (2007). Cognitive and emotion recognition deficits in obsessive-compulsive disorder. Psychiatry Research 149, 121–128.CrossRefGoogle ScholarPubMed

Aycicegi, A, Dinn, WM, Harris, CL, Erkmen, H (2003). Neuropsychological function in obsessive–compulsive disorder: effects of comorbid conditions on task performance. European Psychiatry 18, 241–248.CrossRefGoogle ScholarPubMed

Bohne, A, Savage, CR, Deckersbach, T, Keuthen, NJ, Jenike, MA, Tuschen-Caffier, B, Wilhelm, S (2005). Visuospatial abilities, memory, and executive functioning in trichotillomania and obsessive-compulsive disorder. Journal of Clinical and Experimental Neuropsychology 27, 385–399.CrossRefGoogle ScholarPubMed

Boone, KB, Ananth, J, Philpott, L, Kaur, A (1991). Neuropsychological characteristics of nondepressed adults with obsessive–compulsive disorder. Neuropsychiatry, Neuropsychology and Behavioral Neurology 4, 96–109.Google Scholar

Borges, MC, Braga, DT, Iego, S, D'Alcante, CC, Sidrim, I, Machado, MC, Pinto, PS, Cordioli, AV, do Rosario, MC, Petribu, K, Mendlowicz, MV, Mari, JJ, Miguel, EC, Fontenelle, LF (2011). Cognitive dysfunction in post-traumatic obsessive–compulsive disorder. Australian and New Zealand Journal of Psychiatry 45, 76–85.Google Scholar

Bucci, P, Galderisi, S, Catapano, F, Di Benedetto, R, Piegari, G, Mucci, A, Maj, M (2007). Neurocognitive indices of executive hypercontrol in obsessive-compulsive disorder. Acta Psychiatry Scandinavica 115, 380–387.Google Scholar

Cavallaro, R, Cavedini, P, Mistretta, P, Bassi, T, Angelone, SM, Ubbiali, A, Bellodi, L (2003). Basal-corticofrontal circuits in schizophrenia and obsessive–compulsive disorder: a controlled, double dissociation study. Biological Psychiatry 54, 437–443.Google Scholar

Cavedini, P, Cisima, M, Riboldi, G, D'Annucci, A, Bellodi, L (2001). A neuropsychological study of dissociation in cortical and subcortical functioning in obsessive–compulsive disorder by Tower of Hanoi task. Brain and Cognition 46, 357–363.Google Scholar

Cavedini, P, Gorini, A, Bellodi, L (2006). Understanding obsessive–compulsive disorder: focus on decision making. Neuropsychology Review 16, 3–15.Google Scholar

Cavedini, P, Zorzi, C, Piccinni, M, Cavallini, MC, Bellodi, L (2010). Executive dysfunctions in obsessive–compulsive patients and unaffected relatives: searching for a new intermediate phenotype. Biological Psychiatry 67, 1178–1184.CrossRefGoogle ScholarPubMed

Ceschi, G, Van der Linden, M, Dunker, D, Perroud, A, Bredart, S (2003). Further exploration memory bias in compulsive washers. Behaviour Research and Therapy 41, 737–748.CrossRefGoogle ScholarPubMed

Cha, KR, Koo, MS, Kim, CH, Kim, JW, Oh, WJ, Suh, HS, Lee, HS (2008). Nonverbal memory dysfunction in obsessive–compulsive disorder patients with checking compulsions. Depression and Anxiety 25, E115–E120.Google Scholar

Chamberlain, SR, Blackwell, AD, Fineberg, NA, Robbins, TW, Sahakian, BJ (2005). The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers. Neuroscience and Biobehavioral Reviews 29, 399–419.Google Scholar

Chamberlain, SR, Fineberg, NA, Blackwell, AD, Clark, L, Robbins, TW, Sahakian, BJ (2007). A neuropsychological comparison of obsessive–compulsive disorder and trichotillomania. Neuropsychologia 45, 654–662.Google Scholar

Choi, JS, Kang, DH, Kim, JJ, Ha, TH, Lee, JM, Youn, T, Kim, IY, Kim, SI, Kwon, JS (2004). Left anterior subregion of orbitofrontal cortex volume reduction and impaired organizational strategies in obsessive-compulsive disorder. Journal of Psychiatry Research 38, 193–199.CrossRefGoogle ScholarPubMed

Cohen, J (1988). Statistical Power Analysis for the Behavioral Sciences, 2nd edn. Lawrence Earlbaum: Hillsdale, NJ.Google Scholar

Cohen, Y, Lachenmeyer, JR, Springer, C (2003). Anxiety and selective attention in obsessive–compulsive disorder. Behaviour Research and Therapy 41, 1311–1323.Google Scholar

Deckersbach, T, Savage, CR, Reilly-Harrington, N, Clark, L, Sachs, G, Rauch, SL (2004). Episodic memory impairment in bipolar disorder and obsessive–compulsive disorder: the role of memory strategies. Bipolar Disorders 6, 233–244.Google Scholar

de Geus, F, Denys, DA, Sitskoorn, MM, Westenberg, HG (2007). Attention and cognition in patients with obsessive-compulsive disorder. Psychiatry and Clinical Neurosciences 61, 45–53.Google Scholar

Duval, S, Tweedie, R (2000). Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56, 455–463.CrossRefGoogle ScholarPubMed

Egger, M, Smith, GD, Schneider, M, Minder, C (1997). Bias in meta-analysis detected by a simple, graphical test. BMJ 315, 629–634.Google Scholar

Fenger, MM, Gade, A, Adams, KH, Hansen, ES, Bolwig, TG, Knudsen, GM (2005). Cognitive deficits in obsessive–compulsive disorder on tests of frontal lobe functions. Nordic Journal of Psychiatry 59, 39–44.CrossRefGoogle ScholarPubMed

Gambini, O, Abbruzzese, M, Scarone, S (1993). Smooth pursuit and saccadic eye movements and Wisconsin Card Sorting Test performance in obsessive-compulsive disorder. Psychiatry Research 48, 191–200.Google Scholar

Goncalves, OF, Marques, TR, Lori, NF, Sampaio, A, Branco, MC (2010). Obsessive–compulsive disorder as a visual processing impairment. Medical Hypotheses 74, 107–109.Google Scholar

Hedges, L, Holkin, I (1985). Statistical Methods for Meta-Analysis. Academic Press: New York, NY.Google Scholar

Henin, A, Savage, CR, Rauch, SL, Deckersbach, T, Wilhelm, S, Baer, L, Otto, MW, Jenike, MA (2001). Is age at symptom onset associated with severity of memory impairment in adults with obsessive–compulsive disorder? American Journal of Psychiatry 158, 137–139.Google Scholar

Hur, JW, Shin, NY, Kim, SN, Jang, JH, Choi, JS, Shin, YC, Kwon, JS (2012). Do pathological gambling and obsessive-compulsive disorder overlap? A neurocognitive perspective. CNS Spectrums 17, 207–213.CrossRefGoogle ScholarPubMed

Hwang, SH, Kwon, JS, Shin, YW, Lee, KJ, Kim, YY, Kim, MS (2007). Neuropsychological profiles of patients with obsessive–compulsive disorder: early onset versus late onset. Journal of the International Neuropsychological Society 13, 30–37.Google Scholar

Kitis, A, Akdede, BB, Alptekin, K, Akvardar, Y, Arkar, H, Erol, A, Kaya, N (2007). Cognitive dysfunctions in patients with obsessive-compulsive disorder compared to the patients with schizophrenia patients: relation to overvalued ideas. Progress in Neuro-Psychopharmacology and Biological Psychiatry 31, 254–261.CrossRefGoogle Scholar

Kuelz, AK, Hohagen, F, Voderholzer, U (2004). Neuropsychological performance in obsessive–compulsive disorder: a critical review. Biological Psychology 65, 185–236.Google Scholar

Lacerda, AL, Dalgalarrondo, P, Caetano, D, Haas, GL, Camargo, EE, Keshavan, MS (2003). Neuropsychological performance and regional cerebral blood flow in obsessive-compulsive disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry 27, 657–665.Google Scholar

Lawrence, NS, Wooderson, S, Mataix-Cols, D, David, R, Speckens, A, Phillips, ML (2006). Decision making and set shifting impairments are associated with distinct symptom dimensions in obsessive-compulsive disorder. Neuropsychology 20, 409–419.CrossRefGoogle ScholarPubMed

Lucey, JV, Burness, CE, Costa, DC, Gacinovic, S, Pilowsky, LS, Ell, PJ, Marks, IM, Kerwin, RW (1997). Wisconsin Card Sorting Task (WCST) errors and cerebral blood flow in obsessive-compulsive disorder (OCD). British Journal of Medical Psychology 70 403–411.Google Scholar

Melloni, M, Urbistondo, C, Sedeño, L, Gelormini, C, Kichic, R, Ibanez, A (2012). The extended fronto-striatal model of obsessive compulsive disorder: convergence from event-related potentials, neuropsychology and neuroimaging. Frontiers in Human Neuroscience 6, 259.Google Scholar

Menzies, L, Chamberlain, SR, Laird, AR, Thelen, SM, Sahakian, BJ, Bullmore, ET (2008). Integrating evidence from neuroimaging and neuropsychological studies of obsessive–compulsive disorder: the orbitofronto-striatal model revisited. Neuroscience and Biobehavioral Reviews 32, 525–549.Google Scholar

Muller, J, Roberts, JE (2005). Memory and attention in obsessive–compulsive disorder: a review. Journal of Anxiety Disorders 19, 1–28.Google Scholar

Murphy, R, Nutzinger, DO, Paul, T, Leplow, B (2004). Conditional-associative learning in eating disorders: a comparison with OCD. Journal of Clinical and Experimental Neuropsychology 26, 190–199.Google Scholar

Nakao, T, Nakagawa, A, Yoshiura, T, Nakatani, E, Nabeyama, M, Yoshizato, C, Kudoh, A, Tada, K, Yoshioka, K, Kawamoto, M (2005). A functional MRI comparison of patients with obsessive-compulsive disorder and normal controls during a Chinese character Stroop task. Psychiatry Research 139, 101–114.CrossRefGoogle ScholarPubMed

Nakao, T, Nakagawa, A, Yoshiura, T, Nakatani, E, Nabeyama, M, Sanematsu, H, Togao, O, Yoshioka, K, Tomita, M, Kuroki, T, Kanba, S (2009). Duration effect of obsessive–compulsive disorder on cognitive function: a functional MRI study. Depression and Anxiety 26, 814–823.Google Scholar

Nedeljkovic, M, Kyrios, M, Moulding, R, Doron, G, Wainwright, K, Pantelis, C, Purcell, R, Maruff, P (2009). Differences in neuropsychological performance between subtypes of obsessive–compulsive disorder. Australian New Zealand Journal of Psychiatry 43, 216–226.CrossRefGoogle ScholarPubMed

Nielen, MM, Den Boer, JA (2003). Neuropsychological performance of OCD patients before and after treatment with fluoxetine: evidence for persistent cognitive deficits. Psychological Medicine 33, 917–925.Google Scholar

Olley, A, Malhi, G, Sachdev, P (2007). Memory and executive functioning in obsessive–compulsive disorder: a selective review. Journal of Affective Disorders 104, 15–23.Google Scholar

Penades, R, Catalan, R, Rubia, K, Andres, S, Salamero, M, Gasto, C (2007). Impaired response inhibition in obsessive compulsive disorder. European Psychiatry 22, 404–410.CrossRefGoogle ScholarPubMed

Purcell, R, Maruff, P, Kyrios, M, Pantelis, C (1998). Neuropsychological deficits in obsessive-compulsive disorder: a comparison with unipolar depression, panic disorder, and normal controls. Archives of General Psychiatry 55, 415–423.Google Scholar

Radua, J, van den Heuvel, OA, Surguladze, S, Mataix-Cols, D (2010). Meta-analytical comparison of voxel-based morphometry studies in obsessive–compulsive disorder vs other anxiety disorders. Archives of General Psychiatry 67, 701–711.Google Scholar

Rajender, G, Bhatia, MS, Kanwal, K, Malhotra, S, Singh, TB, Chaudhary, D (2011). Study of neurocognitive endophenotypes in drug-naive obsessive–compulsive disorder patients, their first-degree relatives and healthy controls. Acta Psychiatrica Scandinavica 124, 152–161.Google Scholar

Rampacher, F, Lennertz, L, Vogeley, A, Schulze-Rauschenbach, S, Kathmann, N, Falkai, P, Wagner, M (2010). Evidence for specific cognitive deficits in visual information processing in patients with OCD compared to patients with unipolar depression. Progress in Neuro-psychopharmacology and Biological Psychiatry 34, 984–991.Google Scholar

Roth, RM, Milovan, D, Baribeau, J, O'Connor, K (2005). Neuropsychological functioning in early- and late-onset obsessive–compulsive disorder. Journal of Neuropsychiatry and Clinical Neuroscience 17, 208–213.CrossRefGoogle ScholarPubMed

Savage, CR, Baer, L, Keuthen, NJ, Brown, HD, Rauch, SL, Jenike, MA (1999). Organizational strategies mediate nonverbal memory impairment in obsessive–compulsive disorder. Biological Psychiatry 45, 905–916.Google Scholar

Savage, CR, Deckersbach, T, Wilhelm, S, Rauch, SL, Baer, L, Reid, T, Jenike, MA (2000). Strategic processing and episodic memory impairment in obsessive compulsive disorder. Neuropsychology 14, 141–151.Google Scholar

Schmidtke, K, Schorb, A, Winkelmann, G, Hohagen, F (1998). Cognitive frontal lobe dysfunction in obsessive–compulsive disorder. Biological Psychiatry 43, 666–673.Google Scholar

Segalas, C, Alonso, P, Real, E, Garcia, A, Minambres, A, Labad, J, Pertusa, A, Bueno, B, Jimenez-Murcia, S, Menchon, JM (2010). Memory and strategic processing in first-degree relatives of obsessive compulsive patients. Psychological Medicine 40, 2001–2011.Google Scholar

Shin, MS, Park, SJ, Kim, MS, Lee, YH, Ha, TH, Kwon, JS (2004). Deficits of organizational strategy and visual memory in obsessive–compulsive disorder. Neuropsychology 18, 665–672.Google Scholar

Simpson, HB, Rosen, W, Huppert, JD, Lin, SH, Foa, EB, Liebowitz, MR (2006). Are there reliable neuropsychological deficits in obsessive-compulsive disorder? Journal of Psychiatric Research 40, 247–257.Google Scholar

Starcke, K, Tuschen-Caffier, B, Markowitsch, HJ, Brand, M (2010). Dissociation of decisions in ambiguous and risky situations in obsessive–compulsive disorder. Psychiatry Research 175, 114–120.Google Scholar

Trivedi, JK, Dhyani, M, Goel, D, Sharma, S, Singh, AP, Sinha, PK, Tandon, R (2008). Neurocognitive dysfunction in patients with obsessive compulsive disorder. African Journal of Psychiatry 11, 204–209.Google Scholar

Tukel, R, Gurvit, H, Ertekin, BA, Oflaz, S, Ertekin, E, Baran, B, Kalem, SA, Kandemir, PE, Ozdemiroglu, FA, Atalay, F (2012). Neuropsychological function in obsessive–compulsive disorder. Comprehensive Psychiatry 53, 167–175.Google Scholar

Tumkaya, S, Karadag, F, Oguzhanoglu, NK, Tekkanat, C, Varma, G, Ozdel, O, Atesci, F (2009). Schizophrenia with obsessive–compulsive disorder and obsessive–compulsive disorder with poor insight: a neuropsychological comparison. Psychiatry Research 165, 38–46.Google Scholar

Veale, DM, Sahakian, BJ, Owen, AM, Marks, IM (1996). Specific cognitive deficits in tests sensitive to frontal lobe dysfunction in obsessive-compulsive disorder. Psychological Medicine 26, 1261–1269.Google Scholar

Wobrock, T, Gruber, O, McIntosh, AM, Kraft, S, Klinghardt, A, Scherk, H, Reith, W, Schneider-Axmann, T, Lawrie, SM, Falkai, P, Moorhead, TW (2010). Reduced prefrontal gyrification in obsessive–compulsive disorder. European Archives of Psychiatry and Clinical Neurosciences 260, 455–464.Google Scholar