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Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers - Nature

  • ️Gottlieb, Philip A.
  • ️Thu Jul 08 2004

References

  1. Suchyna, T. M. et al. Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels. J. Gen. Physiol. 115, 583–598 (2000)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Andersen, O. S. et al. Ion channels as tools to monitor lipid bilayer-membrane protein interactions: gramicidin channels as molecular force transducers. Methods Enzymol. 294, 208–224 (1999)

    Article  CAS  PubMed  Google Scholar 

  3. Patel, A. J. et al. Inhalational anesthetics activate two-pore-domain background K+ channels. Nature Neurosci. 2, 422–426 (1999)

    Article  CAS  PubMed  Google Scholar 

  4. Patel, A. J., Lazdunski, M. & Honore, E. Lipid and mechano-gated 2P domain K+ channels. Curr. Opin. Cell Biol. 13, 422–427 (2001)

    Article  CAS  PubMed  Google Scholar 

  5. Perozo, E., Kloda, A., Cortes, D. M. & Martinac, B. Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating. Nature Struct. Biol. 9, 696–703 (2002)

    Article  CAS  PubMed  Google Scholar 

  6. Lundbæk, J. A. & Andersen, O. S. Lysophospholipids modulate channel function by altering the mechanical properties of lipid bilayers. J. Gen. Physiol. 104, 645–673 (1994)

    Article  PubMed  Google Scholar 

  7. Hwang, T. C., Koeppe, R. E. II & Andersen, O. S. Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics. Biochemistry 42, 13646–13658 (2003)

    Article  CAS  PubMed  Google Scholar 

  8. Goulian, M. et al. Gramicidin channel kinetics under tension. Biophys. J. 74, 328–337 (1998)

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  9. Oswald, R. E., Suchyna, T. M., McFeeters, R., Gottlieb, P. & Sachs, F. Solution structure of peptide toxins that block mechanosensitive ion channels. J. Biol. Chem. 277, 34443–34450 (2002)

    Article  CAS  PubMed  Google Scholar 

  10. Ostrow, K. L. et al. cDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels. Toxicon 42, 263–274 (2003)

    Article  CAS  PubMed  Google Scholar 

  11. Markin, V. S. & Sachs, F. Thermodynamics of mechanosensitivity. Physical Biol. (in the press)

  12. Suchyna, T. & Sachs, F. Dynamic regulation of mechanosensitive channels: capacitance used to monitor patch tension in real time. Phys. Biol. 1, 1–18 (2004)

    Article  ADS  CAS  PubMed  Google Scholar 

  13. Ladokhin, A. S., Jayasinghe, S. & White, S. H. How to measure and analyze tryptophan fluorescence in membranes properly, and why bother? Anal. Biochem. 285, 235–245 (2000)

    Article  CAS  PubMed  Google Scholar 

  14. White, S. H., Wimley, W. C., Ladokhin, A. S. & Hristova, K. Protein folding in membranes: determining energetics of peptide-bilayer interactions. Methods Enzymol. 295, 62–87 (1998)

    Article  CAS  PubMed  Google Scholar 

  15. Kim, J., Mosior, M., Chung, L. A., Wu, H. & McLaughlin, S. Binding of peptides with basic residues to membranes containing acidic phospholipids. Biophys. J. 60, 135–148 (1991)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Lundbæk, J. A. & Andersen, O. S. Spring constants for channel-induced lipid bilayer deformations—estimates using gramicidin channels. Biophys. J. 76, 889–895 (1999)

    Article  PubMed  PubMed Central  Google Scholar 

  17. O'Connell, A. M., Koeppe, R. E. II & Andersen, O. S. Kinetics of gramicidin channel formation in lipid bilayers: transmembrane monomer association. Science 250, 1256–1259 (1990)

    Article  ADS  CAS  PubMed  Google Scholar 

  18. Elliott, J. R., Needham, D., Dilger, J. P. & Haydon, D. A. The effects of bilayer thickness and tension on gramicidin single-channel lifetime. Biochim. Biophys. Acta 735, 95–103 (1983)

    Article  CAS  PubMed  Google Scholar 

  19. Huang, H. W. Deformation free energy of bilayer membrane and its effect on gramicidin channel lifetime. Biophys. J. 50, 1061–1070 (1986)

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  20. Koeppe, R. E. II et al. On the helix sense of gramicidin A single channels. Proteins 12, 49–62 (1992)

    Article  CAS  PubMed  Google Scholar 

  21. Trudelle, Y. & Heitz, F. Synthesis and characterization of Tyr(Bzl)9,11,13,15 and Tyr9,11,13,15 gramicidin A. Int. J. Pept. Protein Res. 30, 163–169 (1987)

    Article  CAS  PubMed  Google Scholar 

  22. Lundbæk, J. A. et al. Regulation of sodium channel function by bilayer elasticity the importance of hydrophobic coupling: effects of micelle-forming amphiphiles and cholesterol. J. Gen. Physiol. 123, 599–621 (2004)

    Article  PubMed  PubMed Central  Google Scholar 

  23. Bode, F., Sachs, F. & Franz, M. R. Tarantula peptide inhibits atrial fibrillation. Nature 409, 35–36 (2001)

    Article  ADS  CAS  PubMed  Google Scholar 

  24. Lehtonen, J. Y. & Kinnunen, P. K. Phospholipase A2 as a mechanosensor. Biophys. J. 68, 1888–1894 (1995)

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  25. Gudi, S., Nolan, J. P. & Frangos, J. A. Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition. Proc. Natl Acad. Sci. USA 95, 2515–2519 (1998)

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  26. Laitko, U. & Morris, C. E. Membrane tension accelerates rate-limiting voltage-dependent activation and slow inactivation steps in a Shaker channel. J. Gen. Physiol. 123, 135–154 (2004)

    Article  PubMed  PubMed Central  Google Scholar 

  27. Greathouse, D. V., Koeppe, R. E. II, Providence, L. L., Shobana, S. & Andersen, O. S. Design and characterization of gramicidin channels. Methods Enzymol. 294, 525–550 (1999)

    Article  CAS  PubMed  Google Scholar 

  28. Andersen, O. S. Ion movement through gramicidin A channels. Single-channel measurements at very high potentials. Biophys. J. 41, 119–133 (1983)

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  29. Bett, G. C. & Sachs, F. Activation and inactivation of mechanosensitive currents in the chick heart. J. Membr. Biol. 173, 237–254 (2000)

    Article  CAS  PubMed  Google Scholar 

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