nature.com

A human MSX1 homeodomain missense mutation causes selective tooth agenesis - Nature Genetics

  • ️Seidman, Christine E.
  • ️Thu Aug 01 1996

References

  1. McKusick, V.A. Mendelian Inheritance in Man 11th edn.(The Johns Hopkins University Press, Baltimore, 1994).

    Google Scholar 

  2. Graber, L.W. Congenital absence of teeth: a review with emphasis on inheritance patterns. J. Am. Dent Assoc. 96, 266–275 (1978).

    Article  CAS  Google Scholar 

  3. Gorlin, R., Cohen, M. & Levin, L. Syndromes of the Head and Neck. (Oxford University Press, New York, 1990).

    Google Scholar 

  4. Burzynski, N.J. & Escobar, V.H. Classification and genetics of numeric anomalies of dentition. Birth Defects. 19, 95–106 (1983).

    CAS  PubMed  Google Scholar 

  5. Symons, A.L., Stritzel, F. & Stamatiou, J. Anomalies associated with hypodontia of the permanent lateral incisor and second premolar. J. Clin. Pediat. Dent. 17, 109–111 (1993).

    CAS  Google Scholar 

  6. Sharpe, P.T. Homeobox genes and orofacial development. Connect. Tissue. Res. 32, 17–25 (1995).

    Article  CAS  Google Scholar 

  7. Jowett, A.K., Vainio, S., Ferguson, M.W., Sharpe, P.T. & Thesleff, I. Epithelial-mesenchymal interactions are required for msxl and msx2 gene expression in the developing murine molar tooth. Development 117, 461–470 (1993).

    CAS  Google Scholar 

  8. Robert, B., Sassoon, D., Jacq, B., Gehring, W. & Buckingham, M., Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis. EMBO J. 8, 91–100 (1989).

    Article  CAS  Google Scholar 

  9. Satokata, I. & Maas, R. Msxl deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nature Genet. 6, 348–356 (1994).

    Article  CAS  Google Scholar 

  10. Gyapay, G. et al. The 1993–p94 Généthon human genetic linkage map. Nature Genet. 7, 246–339 (1994).

    Article  CAS  Google Scholar 

  11. Murray, J.C., et al. A comprehensive human linkage map with centimorgan density. Cooperative Human Linkage Center (CHLC). Science 265, 2049–2054 (1994).

    Article  CAS  Google Scholar 

  12. Padanilam, B.J. . et al. Characterization of the human HOX 7 cDNA and identification of polymorphic markers. Hum. Mol. Genet. 1, 407–410 (1992).

    Article  CAS  Google Scholar 

  13. Genome Data Base. Chromosome 4.

  14. Ferguson, M. Craniofacial malformations: towards a molecular understanding. Nature Genet. 6, 329–330 (1994).

    Article  CAS  Google Scholar 

  15. Hewitt, J.E., Clark, L.N., Ivens, A. & Williamson, R. Structure and sequence of the human homeobox gene HOX7. Genomics 11, 670–678 (1991).

    Article  CAS  Google Scholar 

  16. Davidson, D. The function and evolution of Msx genes: pointers and paradoxes. Trends Genet. 11, 405–411 (1995).

    Article  CAS  Google Scholar 

  17. Nieminen, P., Arte, S., Pirinen, S., Peltonen, L. & Thesleff, I. Gene defect in hypodontia: exclusion of MSX1 and MSX2 as candidate genes. Hum. Genet. 96, 305–308 (1995).

    Article  CAS  Google Scholar 

  18. Gehring, W.J. et al. Homeodomain-DNA recognition. Cell 78, 211–223 (1994)

    Article  CAS  Google Scholar 

  19. Muller, M. et al. Isolation and sequence-specific DNA binding of the Antennapedia homeodomain. EMBO J. 7, 4299–4304 (1988).

    Article  CAS  Google Scholar 

  20. Laughon, A. DNA binding specificity of homeodomains. Biochemistry 30, 11357–11367 (1991).

    Article  CAS  Google Scholar 

  21. Zhang, H., Catron, K. & Abate-Shen, C. A role for the Msx-1 homeodomain in transcriptional regulation: Residues in the N-terminal arm mediate TATA binding protein interactions and transcriptional repression. Proc. Natl. Acad. Sci. USA 93, 1764–1769 (1996).

    Article  CAS  Google Scholar 

  22. Watkins, H. et al. A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1 q3. Nature Genet. 3, 333–337 (1993).

    Article  CAS  Google Scholar 

  23. Ausubel, F. et al. Current Protocols in Molecular Biology. (Greene Publishing, New York, 1989).

    Google Scholar 

Download references