Expanding diversity in dynamic combinatorial libraries: simultaneous exchange of disulfide and thioester linkages
- ️Jeremy K. M. Sanders
Abstract
Dynamic combinatorial libraries have been prepared which feature two simultaneous covalent exchange reactions in aqueous solution at neutral pH. This allows for diversity, not only of the subunits that are linked, but also of the linkage itself.
Supplementary files
Article information
- https://doi.org/10.1039/B500638D
- Communication
- 14 Jan 2005
- 09 Feb 2005
- 18 Feb 2005
DOI
Article type
Submitted
Accepted
First published
Chem. Commun., 2005, 1959-1961
Permissions
Expanding diversity in dynamic combinatorial libraries: simultaneous exchange of disulfide and thioester linkages
J. Leclaire, L. Vial, S. Otto and J. K. M. Sanders, Chem. Commun., 2005, 1959 DOI: 10.1039/B500638D
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