Protein Arginine Methyltransferase 5 Functions in Opposite Ways in the Cytoplasm and Nucleus of Prostate Cancer Cells
Figure 8
PRMT5 forms a stoichiometric complex with p44 and PRMT5.
(A) SDS-PAGE of PRMT5 complexes produced by co-expression in E. coli. (B) Methylation of SmD3 and histone H4 substrates by PRMT5 and PRMT5-containing complexes. Top: autoradiography of the gel. Bottom: Coomassie blue staining of the gel.