Increase in cases of Guillain-Barré syndrome during a Chikungunya outbreak, French Polynesia, 2014 to 2015
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- ️Thu Dec 03 2015
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http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2015.20.48.30079
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- 1 , Emmanuel Fournier2 , Isabelle Leparc-Goffart3 , Philippe Larre4 , Stéphanie Cubizolle4 , Chantal Sookhareea4 , Stéphane Lastère5 , Frédéric Ghawche4
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Affiliations:
1 Internal Medicine Department, French Polynesia Tertiary Hospital, Tahiti, French Polynesia
2 Clinical Neurophysiology Department, Pitié Salpétrière, APHP, Paris, France
3 French National Reference Centre for Arboviruses, IRBA, Marseille, France
4 Neurology Department, French Polynesia Tertiary Hospital, Tahiti, French Polynesia
5 Clinical Virology Laboratory, French Polynesia Tertiary Hospital, Tahiti, French Polynesia
Correspondence:
Erwan Oehler
erwan.oehler cht.pf
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Abstract
During the recent chikungunya fever outbreak in French Polynesia in October 2014 to March 2015, we observed an abnormally high number of patients with neurological deficit. Clinical presentation and complementary exams were suggestive of Guillain–Barré syndrome (GBS) for nine patients. All nine had a recent dengue-like syndrome and tested positive for chikungunya virus (CHIKV) in serology or RT-PCR. GBS incidence was increased four- to nine-fold during this period, suggesting a link to CHIKV infection.
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/content/10.2807/1560-7917.ES.2015.20.48.30079
2015-12-03
2025-02-08
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