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The labile nature of consolidation theory - Nature Reviews Neuroscience

  • ️LeDoux, Joseph E.
  • ️Fri Dec 01 2000
  • Müller, G. E. & Pilzecker, A. Experimentelle beitrage zur lehre vom gedachtnis. Z. Psychol. S1, 1–288 (1900).

    Google Scholar 

  • Hebb, D. O. The organization of behavior (Wiley, New York, 1949 ).

    Google Scholar 

  • Nader, K., Schafe, G. E. & LeDoux, J. E. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406, 722–726 (2000).

    Article  CAS  Google Scholar 

  • Sara, S. J. Retrieval and reconsolidation: toward a Neurobiology of remembering. Learn. Mem. 7, 73–84 ( 2000).

    Article  CAS  Google Scholar 

  • Moscovitch, M. & Nadel, L. Consolidation and the hippocampal complex revisited: in defense of the multiple-trace model. Curr. Opin. Neurobiol. 8, 297–300 (1998).

    Article  CAS  Google Scholar 

  • Nadel, L. & Land, C. Memory traces revisited. Nature Rev. Neurosci. 1, 209–212 (2000). Abstract

    Article  CAS  Google Scholar 

  • Miller, R. & Matzel, L. D. Memory involves far more than 'consolidation'. Nature Rev. Neurosci. 1, 214–216 (2000). Abstract

    Article  CAS  Google Scholar 

  • Sara, S. Strengthening the shaky trace through retrieval. Nature Rev. Neurosci. 1, 212–213 (2000). Abstract

    Article  CAS  Google Scholar 

  • Squire, L. R. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol. Rev. 99, 195– 231 (1992); erratum 99, 582 (1992).

    Article  CAS  Google Scholar 

  • McClelland, J. L., McNaughton, B. L. & O'Reilly, R. C. Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory. Psychol. Rev. 102, 419–457 (1995).

    Article  Google Scholar 

  • Knowlton, B. J. & Fanselow, M. S. The hippocampus, consolidation and on-line memory. Curr. Opin. Neurobiol. 8, 293–296 (1998).

    Article  CAS  Google Scholar 

  • Cahill, L. & McGaugh, J. L. Modulation of memory storage . Curr. Opin. Neurobiol. 6, 237– 242 (1996).

    Article  CAS  Google Scholar 

  • DeZazzo, J. & Tully, T. Dissection of memory formation: from behavioral pharmacology to molecular genetics. Trends Neurosci. 18, 212–218 ( 1995).

    Article  CAS  Google Scholar 

  • Dudai, Y. & Morris, R. in Brain, Perception, Memory. Advances in Cognitive Sciences (ed. Bolhius, J.) (Oxford Univ. Press, Oxford, in the press).

  • Bailey, C. H., Bartsch, D. & Kandel, E. R. Toward a molecular definition of long-term memory storage. Proc. Natl Acad. Sci. USA 93, 13445 –13452 (1996).

    Article  CAS  Google Scholar 

  • Davis, H. P. & Squire, L. R. Protein synthesis and memory. A review. Psychol. Bull. 96, 518– 559 (1984).

    Article  CAS  Google Scholar 

  • Agranoff, B. W. in Basic Neurochemistry (eds Siegel, G. J., Albers, R. W., Agranoff, B. W. & Catzman, R.) 801–820 (Little, Brown, Boston, 1981).

    Google Scholar 

  • Flexner, L. B., Flexner, J. B. & Stellar, E. Memory and cerebral protein synthesis in mice as affected by graded amounts of puromycin. Exp. Neurol. 13, 264–272 (1965).

    Article  CAS  Google Scholar 

  • McGaugh, J. L. Memory — a century of consolidation. Science 287, 248–251 (2000).

    Article  CAS  Google Scholar 

  • Munoz, C. & Grossman, S. P. Spatial discrimination, reversal and active or passive avoidance learning in rats with KA-induced neuronal depletions in dorsal hippocampus. Brain Res. Bull. 6, 399–406 (1981).

    Article  CAS  Google Scholar 

  • Quevedo, J. et al. Two time windows of anisomycin-induced amnesia for inhibitory avoidance training in rats: protection from amnesia by pretraining but not pre-exposure to the task apparatus. Learn. Mem. 6, 600–607 (1999).

    Article  CAS  Google Scholar 

  • Roozendaal, B., Quirarte, G. L. & McGaugh, J. L. Stress-activated hormonal systems and the regulation of memory storage. Ann. NY Acad. Sci. 821, 247–258 (1997).

    Article  CAS  Google Scholar 

  • McGaugh, J. L., Cahill, L. & Roozendaal, B. Involvement of the amygdala in memory storage: interaction with other brain systems. Proc. Natl Acad. Sci. USA 93, 13508–13514 (1996).

    Article  CAS  Google Scholar 

  • McGaugh, J. L. Involvement of hormonal and neuromodulatory systems in the regulation of memory storage. Annu. Rev. Neurosci. 12, 255– 287 (1989).

    Article  CAS  Google Scholar 

  • Wilensky, A. E., Schafe, G. E. & LeDoux, J. E. The amygdala modulates memory consolidation of fear-motivated inhibitory avoidance learning but not classical fear conditioning. J. Neurosci. 20, 7059–7066 (2000).

    Article  CAS  Google Scholar 

  • Wilensky, A. E., Schafe, G. E. & LeDoux, J. E. Functional inactivation of the amygdala before but not after auditory fear conditioning prevents memory formation. J. Neurosci. 19, RC48 (1999).

  • Schafe, G. E. & LeDoux, J. E. Memory consolidation of Pavlovian fear conditioning is dependent on protein synthesis and PKA in the lateral and basal amygdala. J. Neurosci. 20, RC96 (2000).

    Article  CAS  Google Scholar 

  • Cahill, L., Weinberger, N. M., Roozendaal, B. & McGaugh, J. L. Is the amygdala a locus of 'conditioned fear'? Some questions and caveats . Neuron 23, 227–228 (1999).

    Article  CAS  Google Scholar 

  • Dudai, Y. Consolidation: Fragility on the road to the engram. Neuron 17, 367–370 (1996).

    Article  CAS  Google Scholar 

  • Duncan, C. P. The retroactive effect of electroconvulsive shock. J. Comp. Physiol. Psychol. 42, 32–44 ( 1949).

    Article  CAS  Google Scholar 

  • McGaugh, J. L. Time-dependent processes in memory storage. Science 153, 1351–1358 (1966).

    Article  CAS  Google Scholar 

  • Misanin, J. R., Miller, R. R. & Lewis, D. J. Retrograde amnesia produced by electroconvulsive shock after reactivation of a consolidated memory trace. Science 160, 203–204 ( 1968).

    Article  Google Scholar 

  • Dawson, R. G. & McGaugh, J. L. Electroconvulsive shock effects on a reactivated memory trace: Further examination. Science 166, 525–527 (1969).

    Article  CAS  Google Scholar 

  • Gordon, W. C. & Spear, N. E. Effect of reactivation of a previously acquired memory on the interaction between memories. J. Exp. Psychol. 99, 349–355 ( 1973).

    Article  CAS  Google Scholar 

  • Fanselow, M. S. & LeDoux, J. E. Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala. Neuron 23, 229– 232 (1999).

    Article  CAS  Google Scholar 

  • LeDoux, J. E. Emotion circuits in the brain. Annu. Rev. Neurosci. 23, 155–184 (2000).

    Article  CAS  Google Scholar 

  • Rescorla, R. A. Pavlovian Second-Order Conditioning: Studies in Associative Learning (Lawrence Erlbaum Associates, Hillsdale, New Jersey, 1980 ).

    Google Scholar 

  • Nadel, L. & Moscovitch, M. Memory consolidation, retrograde amnesia and the hippocampal complex. Curr. Opin. Neurobiol. 7, 217–227 (1997).

    Article  CAS  Google Scholar 

  • Miller, R. & Springer, A. Implications of recovery from experimental amnesia. Psychol. Rev. 81, 470– 473 (1974).

    Article  CAS  Google Scholar 

  • Gold, P. E. & King, R. A. Retrograde amnesia: Storage failure versus retrieval failure. Psychol. Rev. 81, 465–495 (1974).

    Article  CAS  Google Scholar 

  • Milner, B., Squire, L. R. & Kandel, E. R. Cognitive neuroscience and the study of memory. Neuron 20, 445–468 ( 1998).

    Article  CAS  Google Scholar 

  • LeDoux, J. E. The Emotional Brain Simon & Schuster, New York, 1996).

    Google Scholar 

  • Cherkin, A. Retrograde amnesia in the chick: resistance to the reminder. Physiol. Behav. 8, 949–955 ( 1972).

    Article  Google Scholar 

  • Springer, A. D. & Miller, R. R. Retrieval failure induced by electroconvulsive shock: Reversal with dissimilar training and recovery agents. Science 177, 628– 630 (1972).

    Article  CAS  Google Scholar 

  • Martin, K. C. et al. Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage . Cell 91, 927–938 (1997).

    Article  CAS  Google Scholar 

  • Frey, U. & Morris, R. G. Synaptic tagging and long-term potentiation. Nature 385, 533– 536 (1997).

    Article  CAS  Google Scholar 

  • Lewis, D. J. Psychobiology of active and inactive memory. Psychol. Bull. 86, 1054–1083 ( 1979).

    Article  CAS  Google Scholar 

  • Schacter, D. L. The seven sins of memory. Insights from psychology and cognitive neuroscience . Am. Psychol. 54, 182– 203 (1999).

    Article  CAS  Google Scholar