Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
- ️Sebastião Freitas de Medeiros; Bruna Barcelo Barbosa; Matheus Antonio Souto de Medeiros; Márcia Marly Winck Yamamoto
- ️Tue Jul 27 2021
Abstract
The process of ovulation involves multiple and iterrelated genetic, biochemical, and morphological events: cessation of the proliferation of granulosa cells, resumption of oocyte meiosis, expansion of cumulus cell-oocyte complexes, digestion of the follicle wall, and extrusion of the metaphase-II oocyte. The present narrative review examines these interrelated steps in detail. The combined or isolated roles of the folliclestimulating hormone (FSH) and luteinizing hormone (LH) are highlighted. Genes indiced by the FSH genes are relevant in the cumulus expansion, and LH-induced genes are critical for the resumption ofmeiosis and digestion of the follicle wall. A nonhuman model for follicle-wall digestion and oocyte release was provided.
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How to cite this article
Electronic Document Format (Vancouver)
Medeiros SF, Barbosa BB, Medeiros MAS, Yamamoto MMW. Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação. Revista Brasileira de Ginecologia e Obstetrícia 2021;43(6):480-6.
Electronic Document Format (ABNT)
Medeiros, Sebastião Freitas de; Barbosa, Bruna Barcelo; Medeiros, Matheus Antonio Souto de; Yamamoto, Márcia Marly Winck. Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação. Revista Brasileira de Ginecologia e Obstetrícia, v. 43, n. 6, p. 480-486, Jul. 2021.
Electronic Document Format (APA)
Medeiros, S. F. , Barbosa, B. B., Medeiros, M. A. S. , & Yamamoto, M. M. W. (2021). Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação. Revista Brasileira de Ginecologia e Obstetrícia, 43(6), 480-486.
Electronic Document Format (ISO)
Medeiros, Sebastião Freitas de and Barbosa, Bruna Barcelo and Medeiros, Matheus Antonio Souto de and Yamamoto, Márcia Marly Winck. Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação. Revista Brasileira de Ginecologia e Obstetrícia [online]. 2021, vol. 43, n. 6, [cited 2025-02-15], pp.480-486. Available from: <https://journalrbgo.org/article/morphology-and-biochemistry-of-ovulation-morfologia-e-bioquimica-da-ovulacao/>.
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Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação | Abstract
The process of ovulation involves multiple and iterrelated genetic, biochemical, and morphological events: cessation of the proliferation of granulosa cells, resumption of oocyte meiosis, expansion of cumulus cell-oocyte complexes, digestion of the follicle wall, and extrusion of the metaphase-II oocyte. The present narrative review examines these interrelated steps in detail. The combined or isolated roles of the folliclestimulating hormone (FSH) and luteinizing hormone (LH) are highlighted. Genes indiced by the FSH genes are relevant in the cumulus expansion, and LH-induced genes are critical for the resumption ofmeiosis and digestion of the follicle wall. A nonhuman model for follicle-wall digestion and oocyte release was provided.