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Mantle zone

Mantle zone
Germinal centre
Keimzentrum.jpg
Image labeled in German, but "Mantel-zone" visible near center.

The mantle zone (or just mantle) of a lymphatic nodule (or lymphatic follicle) is an outer ring of small lymphocytes surrounding a germinal center.[1]

It is also known as the "corona".[2]

It contains transient lymphocytes.[3]

It is the location of the lymphoma in mantle cell lymphoma.

Pathology

Intermediate magnification micrograph of Castleman disease showing the characteristic expansion of the mantle zone. H&E stain.

Mantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e. Mantle cell lymphoma.

References

External links

v · d · eLymphoid system (TA A13.1–2, TH H3.10, GA 8 and 9)
Primary lymphoid organs
Secondary lymphoid organs

Spleen
(process blood)

Palatine · Lingual · Pharyngeal · Tubal
Tonsillar crypts

lymph flow: Afferent lymph vessels · Cortical sinuses · Medullary sinuses · Efferent lymph vessels

T cells: High endothelial venules

B cells: Primary follicle/Germinal center · Mantle zone · Marginal zone

layers: Capsule/Trabeculae · Subcapsular sinus · Cortex · Paracortex · Medulla (Medullary cord) · Hilum

MALT
(process mucosa)

GALT · Peyer's patch · Germinal center

M: LMO

anat(h, u, t, a, l)/phys/depv

noco/cong/tumr

proc

Categories:

  • Lymphatic system stubs
  • Lymphatic organ anatomy

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