Dermis

Dermis

Dermis
Latin	dermis; corium
Code	TH H3.12.00.1.03001

A graphic representation of the interface between skin epithelium and the underlying connective tissue. Zone B, indicating the region of overlapping projections of epithelium and connective tissue, is the papillary dermis. Zone C, indicating the region of dermis that lies immediately subjacent to the interdigitations of epithelium, is the reticular dermis.

The dermis is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis.^[1] Structural components of the dermis are collagen, elastic fibers, and extrafibrillar matrix (previously called ground substance).^[2]

Contents

• 1 Components of the Dermis
• 2 Stratum papillare
• 3 Stratum reticulare
• 4 Additional images
• 5 See also
• 6 References

Components of the Dermis

The dermis is composed of three major types of cells^[3]: 1. Fibroblasts 2. Macrophages 3. Adipocytes

Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and glycosaminoglycans^[3].

Stratum papillare

The stratum papillare sends conical elevations (papillae) into the epidermis which contain either terminal networks of blood capillaries or tactile Meissner's corpuscles. ^[4]

Stratum reticulare

The stratum reticulare possesses coarser and more regularly arranged collagenous fiber bundles.

Additional images

• 

  Epidermis and dermis of human skin.

• 

  Cross-section of all human skin layers.

See also

• Dermal papillae

References

1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. Pages 1, 11–12. ISBN 0-7216-2921-0.
2. ^ Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 8–9. ISBN 1-4160-3185-5.
3. ^ ^{a b} The Ageing Skin - Structure
4. ^ http://microvet.arizona.edu/Courses/vsc422/secure/VSC422AppledHistologyLabHandout.pdf

v · d · eIntegumentary system (TA A16, TH H3.12, GA 10.1062)
Skin	Epidermis Stratum corneum · Stratum lucidum · Stratum granulosum · Stratum spinosum · Stratum basale Basement membrane zone Basal keratinocyte · Lamina lucida · Lamina densa Skin fields Head campus frontalis, campus parietalis, campus occipitalis, campus temroralis, campus facialis (campus orbitalis, campus nasalis, campus oralis, campus mentalis, campus infraorbitalis, campus buccalis, campus zygomaticus) Neck campus cervicalis anterior (campus submandibularis, campus caroticus, campus omotrachealis, campus submentalis), campus sternocleidomastoideus, campus cervicalis posterior (campus omoclavicularis), campus nuchalis Chest campus presternalis, campus clavipectoralis, campus pectoralis verus, campus mammarius, campus inframammarius, campus axillaris Abdomen campus hypochondriacus, campus epigastricus, campus abdominalis lateralis, campus umbilicalis, campus inguinalis, campus hypogastricus Perineum campus analis, campus urogenitalis
Subcutaneous tissue	Panniculus/Pannus (Panniculus adiposus · Panniculus carnosus) · Stratum membranosum · Loose connective tissue · Superficial fascia
Adnexa	Skin glands Sweat glands: Apocrine sweat gland · Eccrine sweat gland Sebaceous Hair Root sheath Outer root sheath · Inner root sheath (Henle's layer, Huxley's layer) Hair shaft Cuticle · Cortex · Medulla · Bulb with matrix cells · Hair follicle Muscle Arrector pili muscle Pilosebaceous unit Hair sebaceous gland Nail Nail matrix · Nail plate (Lunula)  · Eponychium · Paronychium · Hyponychium
M: INT, SF, LCT anat/phys/devp noco(i/b/d/q/u/r/p/m/k/v/f)/cong/tumr(n/e/d), sysi/epon proc, drug (D2/3/4/5/8/11) M: SKA anat/phys/devp noco/cong/tumr, sysi/epon proc, drug(D10)

v · d · eHistology: connective tissue (TH H2.00.03)
Composition	Cells Resident Fibroblast · Fibrocyte · Reticular cell · Tendon cell Adipocyte Melanocyte Wandering cell Mast cell · Macrophage Extracellular matrix (noncellular) Ground substance Tissue fluid Fibers Collagen fibers Reticular fibers: COL3A1 Elastic fibers: Elastin · Fibrillin (FBN1, FBN2, FBN3) · EMILIN1 Elaunin
Classification	Connective tissue proper Loose Reticular · Adipose (Brown, White) Dense Dense irregular connective tissue (Submucosa, Dermis) · Dense regular connective tissue (Ligament, Tendon, Aponeurosis) Embryonic Mucoid · Mesenchymal Specialized Cartilage · Bone
Related	Soft tissue
see also Template:Soft tissue tumors and sarcomas M: INT, SF, LCT anat/phys/devp noco(i/b/d/q/u/r/p/m/k/v/f)/cong/tumr(n/e/d), sysi/epon proc, drug (D2/3/4/5/8/11) M: MUS, DF+DRCT anat (h/n, u, t/d, a/p, l)/phys/devp/hist noco(m, s, c)/cong(d)/tumr, sysi/epon, injr proc, drug (M1A/3)

v · d · eRoutes of administration / Dosage forms
Oral	Digestive tract (enteral) Solids Pill Tablet Capsule Time release technology Osmotic controlled release capsule (OROS) Liquids Solution Softgel Suspension Emulsion Syrup Elixir Tincture Hydrogel Buccal / Sublabial / Sublingual Solids Orally Disintegrating Tablet (ODT) Film Lollipop Lozenges Chewing gum Liquids Mouthwash Toothpaste Ointment Oral spray Respiratory tract Solids Smoking device Dry Powder Inhaler (DPI) Liquids pressurized Metered Dose Inhaler (pMDI) Nebulizer Vaporizer Gas Oxygen mask Oxygen concentrator Anaesthetic machine Relative analgesia machine
Ocular / Otologic / Nasal	Nasal spray Ear drops Eye drops Ointment Hydrogel Nanosphere suspension Mucoadhesive microdisc (microsphere tablet)
Urogenital	Ointment Pessary (vaginal suppository) Vaginal ring Vaginal douche Intrauterine device (IUD) Extra-amniotic infusion Intravesical infusion
Rectal (enteral)	Ointment Suppository Enema (Solution • Hydrogel) Murphy drip Nutrient enema
Dermal	Ointment Liniment Paste Film Hydrogel Liposomes Transfersome vesicals Cream Lotion Lip balm Medicated shampoo Dermal patch Transdermal patch Transdermal spray Jet injector
Injection / Infusion (into tissue/blood)	Skin Intradermal Subcutaneous Transdermal implant Organs Intracavernous Intravitreal Intra-articular or intrasynovial injection Transscleral Central nervous system Intracerebral Intrathecal Epidural Circulatory / Musculoskeletal Intravenous Intracardiac Intramuscular Intraosseous Intraperitoneal Nanocell injection
Additional explanation:	Mucous membranes are used by the human body to absorb the dosage for all routes of administration, except for "Dermal" and "Injection/Infusion". Administration routes can also be grouped as Topical (local effect) or Systemic (defined as Enteral = Digestive tract/Rectal, or Parenteral = All other routes).

v · d · eRoutes of administration by organ system
Gastrointestinal	Oral • Buccal • Sublabial • Sublingual • Rectal
Respiratory system	Pulmonary • Nasal
Visual system / Auditory system	Ocular (Ocular-topical / Intravitreal / Transscleral) • Otologic (Oto-topical)
Reproductive system	Intracavernous • Intravaginal • Intrauterine (Extra-amniotic)
Urinary system	Intravesical
Peritoneum	Intraperitoneal
Central nervous system	Intracerebral • Intrathecal • Epidural
Circulatory system	Intravenous • Intracardiac
Musculoskeletal system	Intramuscular • Intraosseous
Skin	Epicutaneous • Intradermal • Subcutaneous

Categories:

• Skin anatomy
• Routes of administration
• Dermatology stubs

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Look at other dictionaries:

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• Dermis — ⇒ Corium …   Deutsch wörterbuch der biologie

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