APAF1, the Glossary

Table of Contents

1. 17 relations: Alternative splicing, APIP, Apoptosis, Apoptosome, ATPase, Autocatalysis, Bcl-2-like protein 1, CARD (domain), Caspase-9, Cytochrome c, Deoxyadenosine triphosphate, Guy Salvesen, HSPA4, NLRP1, Protein–protein interaction, WD40 repeat, Xiaodong Wang (biochemist).

2. Apoptosis

Alternative splicing

Alternative splicing, or alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single gene to produce different splice variants.

See APAF1 and Alternative splicing

APIP

APAF1-interacting protein is a protein that in humans is encoded by the APIP gene.

See APAF1 and APIP

Apoptosis

Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. APAF1 and Apoptosis are programmed cell death.

See APAF1 and Apoptosis

Apoptosome

The apoptosome is a large quaternary protein structure formed in the process of apoptosis. APAF1 and apoptosome are apoptosis and programmed cell death.

See APAF1 and Apoptosome

ATPase

ATPases (Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion or the inverse reaction.

See APAF1 and ATPase

Autocatalysis

In chemistry, a chemical reaction is said to be autocatalytic if one of the reaction products is also a catalyst for the same reaction.

See APAF1 and Autocatalysis

Bcl-2-like protein 1

Bcl-2-like protein 1 is a protein encoded in humans by the BCL2L1 gene. APAF1 and Bcl-2-like protein 1 are apoptosis.

See APAF1 and Bcl-2-like protein 1

CARD (domain)

Caspase recruitment domains, or caspase activation and recruitment domains (CARDs), are interaction motifs found in a wide array of proteins, typically those involved in processes relating to inflammation and apoptosis. APAF1 and CARD (domain) are programmed cell death.

See APAF1 and CARD (domain)

Caspase-9

Caspase-9 is an enzyme that in humans is encoded by the CASP9 gene.

See APAF1 and Caspase-9

Cytochrome c

The cytochrome complex, or cyt c, is a small hemeprotein found loosely associated with the inner membrane of the mitochondrion where it plays a critical role in cellular respiration. APAF1 and cytochrome c are programmed cell death.

See APAF1 and Cytochrome c

Deoxyadenosine triphosphate

Deoxyadenosine triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.

See APAF1 and Deoxyadenosine triphosphate

Guy Salvesen

Guy Salvesen is a South African-born biochemist, best known for his work in the field of apoptosis.

See APAF1 and Guy Salvesen

HSPA4

Heat shock 70 kDa protein 4 is a protein that in humans is encoded by the HSPA4 gene.

See APAF1 and HSPA4

NLRP1

NLRP1 encodes NACHT, LRR, FIIND, CARD domain and PYD domains-containing protein 1 in humans.

See APAF1 and NLRP1

Protein–protein interaction

Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect.

See APAF1 and Protein–protein interaction

WD40 repeat

The WD40 repeat (also known as the WD or beta-transducin repeat) is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide.

See APAF1 and WD40 repeat

Xiaodong Wang (biochemist)

Xiaodong Wang (born 1963) is a Chinese-American biochemist best known for his work with apoptosis, one of the ways through which cells kill themselves.

See APAF1 and Xiaodong Wang (biochemist)

See also

Apoptosis

• ACAMPs
• APAF1
• ASK1
• Anoikis
• Anti-apoptotic Ras signalling cascade
• Apo2.7
• Apoptosis
• Apoptosis regulator BAX
• Apoptosis-inducing factor
• Apoptosome
• Apoptotic DNA fragmentation
• Athanogene
• BH3 interacting-domain death agonist
• Bcl-2
• Bcl-2 homologous antagonist killer
• Bcl-2-like protein 1
• Bcl-xL
• BinCARD
• Caspase
• Caspase-activated DNase
• Cell-mediated immunity
• DNA laddering
• Death domain
• Death-inducing signaling complex
• Dependence receptor
• Early 35 kDa protein
• Identification of cell death
• Mitochondrial apoptosis-induced channel
• Mitochondrial outer membrane permeabilization
• P53
• P53 upregulated modulator of apoptosis
• Phorbol-12-myristate-13-acetate-induced protein 1
• Programmed cell death
• Proteasome
• Pseudoapoptosis
• Sf caspase-1
• T helper cell
• TNF receptor superfamily
• TP53-inducible glycolysis and apoptosis regulator
• XIAP

References

[1] https://en.wikipedia.org/wiki/APAF1

Also known as APAF1 (gene), Apaf-1, Apoptotic peptidase activating factor 1.