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Almotriptan, the Glossary

Almotriptan (trade name Axert and others) is a triptan medication discovered and developed by Almirall for the treatment of heavy migraine headache.^[1]

34 relations: Almirall, Aura (symptom), Bioavailability, Biological half-life, Clearance (pharmacology), Cmax (pharmacology), Coronary artery disease, CYP2D6, CYP3A4, Ergotamine, Fluoxetine, Hypertension, Liver, Medication, Medication package insert, Migraine, Moclobemide, Monoamine oxidase A, Nausea, Oral administration, Peripheral artery disease, Pharmacokinetics, Phonophobia, Photophobia, Placebo, Propranolol, Sex, Stroke, Sumatriptan, Transient ischemic attack, Triptan, Vasoconstriction, Verapamil, 5-HT receptor.
5-HT1D agonists
Triptans

Almirall

Almirall, S.A. is a Spanish pharmaceutical company dedicated to medical dermatology, with headquarters in Barcelona, founded in 1944.

See Almotriptan and Almirall

Aura (symptom)

An aura is a perceptual disturbance experienced by some with epilepsy or migraine.

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Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

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Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (Cmax) to half of Cmax in the blood plasma.

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Clearance (pharmacology)

In pharmacology, clearance (Cl_) is a pharmacokinetic parameter representing the efficiency of drug elimination.

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Cmax (pharmacology)

Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administered and before the administration of a second dose.

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Coronary artery disease

Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart.

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CYP2D6

Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.

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CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans is encoded by CYP3A4 gene.

See Almotriptan and CYP3A4

Ergotamine

Ergotamine, sold under the brand name Ergomar among others, is an ergopeptine and part of the ergot family of alkaloids; it is structurally and biochemically closely related to ergoline.

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Fluoxetine

Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

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Hypertension

Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

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Medication

A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Medication package insert

A package insert is a document included in the package of a medication that provides information about that drug and its use.

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Migraine

Migraine is a genetically influenced complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea and light and sound sensitivity.

See Almotriptan and Migraine

Moclobemide

Moclobemide, sold under the brand names Amira, Aurorix, Clobemix, Depnil and Manerix among others, is a reversible inhibitor of monoamine oxidase A (RIMA) drug primarily used to treat depression and social anxiety. It is not approved for use in the United States, but is approved in other Western countries such as Canada, the UK and Australia.

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Monoamine oxidase A

Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene.

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Nausea

Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit.

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Oral administration

| name.

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Peripheral artery disease

Peripheral artery disease (PAD) is a vascular disorder that causes abnormal narrowing of arteries other than those that supply the heart or brain.

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration.

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Phonophobia

Phonophobia, also called ligyrophobia or sonophobia, is a fear of or aversion to loud sounds (for example firecrackers)—a type of specific phobia.

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Photophobia

Photophobia is a medical symptom of abnormal intolerance to visual perception of light.

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Placebo

A placebo is a substance or treatment which is designed to have no therapeutic value.

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Propranolol

Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker class. It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors, as well to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks.

See Almotriptan and Propranolol

References

[1] https://en.wikipedia.org/wiki/Almotriptan

Also known as ATC code N02CC05, ATCvet code QN02CC05, Almatriptan, Almogran, Almotriptan Malate, Axert.

Almotriptan, the Glossary

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