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Antimalarial medication, the Glossary

Index Antimalarial medication

Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women.[1]

Table of Contents

  1. 177 relations: Abortifacient, Affective spectrum, Alkaloid, Amazon Malaria Initiative, Amodiaquine, Anemia, Animal disease model, Anorexia (symptom), Anti-inflammatory, Antifolate, Antiparasitic, Antipyretic, Anxiety disorder, Apicomplexan life cycle, Arrhythmia, Artemether, Artemether/lumefantrine, Artemisia annua, Artemisinin, Artemotil, Artesunate, Artesunate/amodiaquine, Artesunate/pyronaridine, AstraZeneca, Atovaquone, Atovaquone/proguanil, Atrioventricular block, Bacteriostatic agent, Biguanide, Biocrystallization, Blood plasma, Bradycardia, Cardiotoxicity, Carl Warburg, Cell division, Chemoprophylaxis, Chloroquine, Chlorproguanil, Cinchona, Cinchonism, Circulatory system, Clindamycin, Clostridioides difficile, Colitis, Combination therapy, Cycloguanil, Cytotoxicity, Dapsone, Delirium, Diethyl ether, ... Expand index (127 more) »

Abortifacient

An abortifacient ("that which will cause a miscarriage" from Latin: abortus "miscarriage" and faciens "making") is a substance that induces abortion.

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Affective spectrum

The affective spectrum is a spectrum of mood disorders.

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Alkaloid

Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom.

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Amazon Malaria Initiative

The Amazon Malaria Initiative (AMI) was a regional program that was created in 2001 by several countries sharing the Amazon basin with technical support from PAHO/WHO and financial support from the U.S. Agency for International Development (USAID), and managed by USAID/Peru as part of its South American Regional Infectious Disease Program (SARI).

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Amodiaquine

Amodiaquine (ADQ) is a medication used to treat malaria, including Plasmodium falciparum malaria when uncomplicated. Antimalarial medication and Amodiaquine are antimalarial agents.

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Anemia

Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen.

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Animal disease model

An animal model (short for animal disease model) is a living, non-human, often genetic-engineered animal used during the research and investigation of human disease, for the purpose of better understanding the disease process without the risk of harming a human.

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Anorexia (symptom)

Anorexia is a medical term for a loss of appetite.

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Anti-inflammatory

Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling.

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Antifolate

Antifolates are a class of antimetabolite medications that antagonise (that is, block) the actions of folic acid (vitamin B9).

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Antiparasitic

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases, such as those caused by helminths, amoeba, ectoparasites, parasitic fungi, and protozoa, among others.

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Antipyretic

An antipyretic (from anti- 'against' and 'feverish') is a substance that reduces fever.

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Anxiety disorder

Anxiety disorders are a group of mental disorders characterized by significant and uncontrollable feelings of anxiety and fear such that a person's social, occupational, and personal functions are significantly impaired.

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Apicomplexan life cycle

Apicomplexans, a group of intracellular parasites, have life cycle stages that allow them to survive the wide variety of environments they are exposed to during their complex life cycle.

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Arrhythmia

Arrhythmias, also known as cardiac arrhythmias, are irregularities in the heartbeat, including when it is too fast or too slow.

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Artemether

Artemether is a medication used for the treatment of malaria. Antimalarial medication and Artemether are antimalarial agents.

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Artemether/lumefantrine

Artemether/lumefantrine, sold under the trade name Coartem among others, is a combination of the two medications artemether and lumefantrine. Antimalarial medication and Artemether/lumefantrine are antimalarial agents.

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Artemisia annua

Artemisia annua, also known as sweet wormwood, sweet annie, sweet sagewort, annual mugwort or annual wormwood, is a common type of wormwood native to temperate Asia, but naturalized in many countries including scattered parts of North America.

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Artemisinin

Artemisinin and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to Plasmodium falciparum. Antimalarial medication and Artemisinin are antimalarial agents.

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Artemotil

Artemotil (INN; also known as β-arteether), is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant ''Plasmodium falciparum'' malaria and cerebral malaria cases. Antimalarial medication and Artemotil are antimalarial agents.

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Artesunate

Artesunate (AS) is a medication used to treat malaria. Antimalarial medication and Artesunate are antimalarial agents.

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Artesunate/amodiaquine

Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria. Antimalarial medication and Artesunate/amodiaquine are antimalarial agents.

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Artesunate/pyronaridine

Artesunate/pyronaridine, sold under the brand name Pyramax, is a fixed-dose combination medication for the treatment of malaria.

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AstraZeneca

AstraZeneca plc (AZ) is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, England.

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Atovaquone

Atovaquone, sold under the brand name Mepron, is an antimicrobial medication for the prevention and treatment of ''Pneumocystis jirovecii'' pneumonia (PCP). Antimalarial medication and Atovaquone are antimalarial agents.

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Atovaquone/proguanil

Atovaquone/proguanil, sold under the brand name Malarone among others, is a fixed-dose combination medication used to treat and prevent malaria, including chloroquine-resistant malaria. Antimalarial medication and Atovaquone/proguanil are antimalarial agents.

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Atrioventricular block

Atrioventricular block (AV block) is a type of heart block that occurs when the electrical signal traveling from the atria, or the upper chambers of the heart, to ventricles, or the lower chambers of the heart, is impaired.

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Bacteriostatic agent

A bacteriostatic agent or bacteriostat, abbreviated Bstatic, is a biological or chemical agent that stops bacteria from reproducing, while not necessarily killing them otherwise.

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Biguanide

Biguanide is the organic compound with the formula HN(C(NH)NH2)2.

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Biocrystallization

Biocrystallization is the formation of crystals from organic macromolecules by living organisms.

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Blood plasma

Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but which contains proteins and other constituents of whole blood in suspension.

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Bradycardia

Bradycardia, also called bradyarrhythmia, is a resting heart rate under 60 beats per minute (BPM).

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Cardiotoxicity

Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity.

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Carl Warburg

Carl Warburg (c. 1805–1892), also known as Charles Warburg, was a physician and scientist.

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Cell division

Cell division is the process by which a parent cell divides into two daughter cells.

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Chemoprophylaxis

Chemoprevention or chemoprophylaxis refers to the administration of a medication for the purpose of preventing disease or infection.

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Chloroquine

Chloroquine is a medication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects. Antimalarial medication and Chloroquine are antimalarial agents.

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Chlorproguanil

Chlorproguanil is an antimalarial drug. Antimalarial medication and Chlorproguanil are antimalarial agents.

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Cinchona

Cinchona (pronounced or) is a genus of flowering plants in the family Rubiaceae containing at least 23 species of trees and shrubs. Antimalarial medication and Cinchona are antimalarial agents.

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Cinchonism

Cinchonism is a pathological condition caused by an overdose of quinine or its natural source, cinchona bark.

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Circulatory system

The circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate.

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Clindamycin

Clindamycin is a lincosamide antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infections), and endocarditis.

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Clostridioides difficile

Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer.

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Colitis

Colitis is swelling or inflammation of the large intestine (colon).

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Combination therapy

Combination therapy or polytherapy is therapy that uses more than one medication or modality.

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Cycloguanil

Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in vivo has been thought to be primarily responsible for the antimalarial activity of proguanil. Antimalarial medication and Cycloguanil are antimalarial agents.

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Cytotoxicity

Cytotoxicity is the quality of being toxic to cells.

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Dapsone

Dapsone, also known as 4,4'-sulfonyldianiline (SDA) or diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.

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Delirium

Delirium (formerly acute confusional state, an ambiguous term which is now discouraged) is a specific state of acute confusion attributable to the direct physiological consequence of a medical condition, effects of a psychoactive substance, or multiple causes, which usually develops over the course of hours to days.

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Diethyl ether

Diethyl ether, or simply ether, is an organic compound with the chemical formula, sometimes abbreviated as.

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Dihydroartemisinin

Dihydroartemisinin (also known as dihydroqinghaosu, artenimol or DHA) is a drug used to treat malaria. Antimalarial medication and Dihydroartemisinin are antimalarial agents.

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Dihydrofolate reductase

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as an electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.

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Dihydropteroate synthase

Dihydropteroate synthase (DHPS) is an enzyme classified under.

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Diospyros melanoxylon

Diospyros melanoxylon, the Coromandel ebony or East Indian ebony, is a species of flowering tree in the family Ebenaceae native to India and Sri Lanka; it has a hard, dry bark.

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Disease

A disease is a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to any external injury.

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Disease vector

In epidemiology, a disease vector is any living agent that carries and transmits an infectious pathogen such as a parasite or microbe, to another living organism.

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DNA

Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.

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DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

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Doxycycline

Doxycycline is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. Antimalarial medication and Doxycycline are antimalarial agents.

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Drug of last resort

A drug of last resort (DoLR), also known as a heroic dose, is a pharmaceutical drug which is tried after all other drug options have failed to produce an adequate response in the patient.

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Drug resistance

Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition.

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Drug-induced hyperthermia

Drug-induced fever is a symptom of an adverse drug reaction wherein the administration of drugs intended to help a patient causes a hypermetabolic state resulting in fever.

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Endemic (epidemiology)

In epidemiology, an infection is said to be endemic in a specific population or populated place when that infection is constantly present, or maintained at a baseline level, without extra infections being brought into the group as a result of travel or similar means.

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Esophagitis

Esophagitis, also spelled oesophagitis, is a disease characterized by inflammation of the esophagus.

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Ether

In organic chemistry, ethers are a class of compounds that contain an ether group—an oxygen atom bonded to two organyl groups (e.g., alkyl or aryl).

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Evolution

Evolution is the change in the heritable characteristics of biological populations over successive generations.

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Folate

Folate, also known as vitamin B9 and folacin, is one of the B vitamins.

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Gamete

A gamete (ultimately) is a haploid cell that fuses with another haploid cell during fertilization in organisms that reproduce sexually.

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Gametocyte

A gametocyte is a eukaryotic germ cell that divides by mitosis into other gametocytes or by meiosis into gametids during gametogenesis.

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Ge Hong

Ge Hong (b. 283 – d. 343 or 364), courtesy name Zhichuan (稚川), was a Chinese linguist, philosopher, physician, politician, and writer during the Eastern Jin dynasty.

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Glucose-6-phosphate dehydrogenase

Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) is a cytosolic enzyme that catalyzes the chemical reaction This enzyme participates in the pentose phosphate pathway (see image), a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the reduced form of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH).

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Granulocyte

Granulocytes are cells in the innate immune system characterized by the presence of specific granules in their cytoplasm.

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Half-life

Half-life (symbol) is the time required for a quantity (of substance) to reduce to half of its initial value.

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Halofantrine

Halofantrine is a drug used to treat malaria. Antimalarial medication and Halofantrine are antimalarial agents.

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Heme

Heme (American English), or haem (Commonwealth English, both pronounced /hi:m/), is a ring-shaped iron-containing molecular component of hemoglobin, which is necessary to bind oxygen in the bloodstream.

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Hemolytic anemia

Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular).

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Hemozoin

Haemozoin is a disposal product formed from the digestion of blood by some blood-feeding parasites.

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Hydroxy group

In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula and composed of one oxygen atom covalently bonded to one hydrogen atom.

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Hydroxychloroquine

Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth, often in the form of hydroxychloroquine sulfate. Antimalarial medication and hydroxychloroquine are antimalarial agents.

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Hypoglycemia

Hypoglycemia, also called low blood sugar, is a fall in blood sugar to levels below normal, typically below 70 mg/dL (3.9 mmol/L).

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Immunodeficiency

Immunodeficiency, also known as immunocompromisation, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent.

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Indoor residual spraying

Indoor residual spraying or IRS is the process of spraying the inside of dwellings with an insecticide to kill mosquitoes that spread malaria.

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Infrastructure

Infrastructure is the set of facilities and systems that serve a country, city, or other area, and encompasses the services and facilities necessary for its economy, households and firms to function.

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Insect repellent

An insect repellent (also commonly called "bug spray") is a substance applied to the skin, clothing, or other surfaces to discourage insects (and arthropods in general) from landing or climbing on that surface.

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Insecticide

Insecticides are pesticides used to kill insects.

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Insulin

Insulin (from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (INS) gene.

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Intermittent preventive therapy

Intermittent preventive therapy or intermittent preventive treatment (IPT) is a public health intervention aimed at treating and preventing malaria episodes in infants (IPTi), children (IPTc), schoolchildren (IPTsc) and pregnant women (IPTp).

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Intramuscular injection

Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle.

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Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

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Itch

An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch.

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Kidney failure

Kidney failure, also known as end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and chronic kidney failure, which develops slowly and can often be irreversible.

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Lincomycin

Lincomycin is a lincosamide antibiotic that comes from the actinomycete Streptomyces lincolnensis.

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Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

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Long QT syndrome

Long QT syndrome (LQTS) is a condition affecting repolarization (relaxing) of the heart after a heartbeat, giving rise to an abnormally lengthy QT interval.

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Lumefantrine

Lumefantrine (or benflumetol) is an antimalarial drug. Antimalarial medication and Lumefantrine are antimalarial agents.

See Antimalarial medication and Lumefantrine

Lupus erythematosus

Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues.

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Maceration (cooking)

Maceration is the process of preparing foods through the softening or breaking into pieces using a liquid.

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Malaria

Malaria is a mosquito-borne infectious disease that affects vertebrates.

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Malaria prophylaxis

Malaria prophylaxis is the preventive treatment of malaria.

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Malaria vaccine

Malaria vaccines are vaccines that prevent malaria, a mosquito-borne infectious disease which affected an estimated 249 million people globally in 85 malaria endemic countries and areas and caused 608,000 deaths in 2022.

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Martindale: The Complete Drug Reference

Martindale: The Complete Drug Reference is a reference book published by Pharmaceutical Press listing some 6,000 drugs and medicines used throughout the world, including details of over 125,000 proprietary preparations.

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Medicines for Malaria Venture

Medicines for Malaria Venture (MMV) is a not-for-profit public-private partnership that was established as a foundation in Switzerland in 1999.

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Mefloquine

Mefloquine, sold under the brand name Lariam among others, is a medication used to prevent or treat malaria. Antimalarial medication and Mefloquine are antimalarial agents.

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Merck Veterinary Manual

The Merck Veterinary Manual is a reference manual of animal health care.

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In biochemistry, a metabolite is an intermediate or end product of metabolism.

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Methyl group

In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula (whereas normal methane has the formula). In formulas, the group is often abbreviated as Me.

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Mosquito net

A mosquito net is a type of meshed curtain that is circumferentially draped over a bed or a sleeping area, to offer the sleeper barrier protection against bites and stings from mosquitos, flies, and other pest insects, and thus against the diseases they may carry.

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Multiple drug resistance

Multiple drug resistance (MDR), multidrug resistance or multiresistance is antimicrobial resistance shown by a species of microorganism to at least one antimicrobial drug in three or more antimicrobial categories.

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Mutation

In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA.

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Myeloid tissue

Myeloid tissue, in the bone marrow sense of the word myeloid (myelo- + -oid), is tissue of bone marrow, of bone marrow cell lineage, or resembling bone marrow, and myelogenous tissue (myelo- + -genous) is any tissue of, or arising from, bone marrow; in these senses the terms are usually used synonymously, as for example with chronic myeloid/myelogenous leukemia.

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Natural product

A natural product is a natural compound or substance produced by a living organism—that is, found in nature.

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Neurotoxicity

Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.

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Neutropenia

Neutropenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood.

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Nucleic acid

Nucleic acids are large biomolecules that are crucial in all cells and viruses.

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Ossification

Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts.

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Oxytetracycline

Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered.

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Papua New Guinea

Papua New Guinea, officially the Independent State of Papua New Guinea, is a country in Oceania that comprises the eastern half of the island of New Guinea and its offshore islands in Melanesia (a region of the southwestern Pacific Ocean north of Australia).

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Parasitemia

Parasitemia is the quantitative content of parasites in the blood.

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Peru

Peru, officially the Republic of Peru, is a country in western South America. It is bordered in the north by Ecuador and Colombia, in the east by Brazil, in the southeast by Bolivia, in the south by Chile, and in the south and west by the Pacific Ocean. Peru is a megadiverse country with habitats ranging from the arid plains of the Pacific coastal region in the west to the peaks of the Andes mountains extending from the north to the southeast of the country to the tropical Amazon basin rainforest in the east with the Amazon River.

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PH

In chemistry, pH, also referred to as acidity or basicity, historically denotes "potential of hydrogen" (or "power of hydrogen").

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration.

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Phenotypic plasticity

Phenotypic plasticity refers to some of the changes in an organism's behavior, morphology and physiology in response to a unique environment.

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Photosensitivity

Photosensitivity is the amount to which an object reacts upon receiving photons, especially visible light.

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Piperaquine

Piperaquine is an antiparasitic drug used in combination with dihydroartemisinin to treat malaria. Piperaquine was developed under the Chinese National Malaria Elimination Programme in the 1960s and was adopted throughout China as a replacement for the structurally similar antimalarial drug chloroquine. Antimalarial medication and Piperaquine are antimalarial agents.

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Plasmodium

Plasmodium is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects.

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Plasmodium falciparum

Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.

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Plasmodium malariae

Plasmodium malariae is a parasitic protozoan that causes malaria in humans.

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Plasmodium ovale

Plasmodium ovale is a species of parasitic protozoon that causes tertian malaria in humans.

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Plasmodium vivax

Plasmodium vivax is a protozoal parasite and a human pathogen.

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Point mutation

A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism's genome.

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Poultry

Poultry are domesticated birds kept by humans for the purpose of harvesting animal products such as meat, eggs or feathers.

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Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

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Primaquine

Primaquine is a medication used to treat and prevent malaria and to treat ''Pneumocystis'' pneumonia. Antimalarial medication and Primaquine are antimalarial agents.

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Proguanil

Proguanil, also known as chlorguanide and chloroguanide, is a medication used to treat and prevent malaria. Antimalarial medication and Proguanil are antimalarial agents.

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Project 523

Project 523 is a code name for a 1967 secret military project of the People's Republic of China to find antimalarial medications. Antimalarial medication and project 523 are antimalarial agents.

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Prokaryotic small ribosomal subunit

The prokaryotic small ribosomal subunit, or 30S subunit, is the smaller subunit of the 70S ribosome found in prokaryotes.

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Protein biosynthesis

Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation or export) through the production of new proteins.

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Psoriasis

Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin.

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Psychosis

Psychosis is a condition of the mind or psyche that results in difficulties determining what is real and what is not real.

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Public health

Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals".

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Purine

Purine is a heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together.

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Pyrimethamine

Pyrimethamine, sold under the brand name Daraprim among others, is a medication used with leucovorin (leucovorin is used to decrease side effects of pyrimethamine; it does not have intrinsic anti-parasitic activity) to treat the parasitic diseases toxoplasmosis and cystoisosporiasis. Antimalarial medication and pyrimethamine are antimalarial agents.

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Pyrimidine

Pyrimidine is an aromatic, heterocyclic, organic compound similar to pyridine.

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Quinidine

Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances.

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Quinine

Quinine is a medication used to treat malaria and babesiosis. Antimalarial medication and Quinine are antimalarial agents.

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Respiratory system

The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants.

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Retinopathy

Retinopathy is any damage to the retina of the eyes, which may cause vision impairment.

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Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

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Ribosome

Ribosomes are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation).

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Route of administration

In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body.

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Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is unintended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

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Sinus arrhythmia

Sinus arrhythmia is a commonly encountered variation of normal sinus rhythm.

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Stereoisomerism

In stereochemistry, stereoisomerism, or spatial isomerism, is a form of isomerism in which molecules have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space.

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Sub-Saharan Africa

Sub-Saharan Africa, Subsahara, or Non-Mediterranean Africa is the area and regions of the continent of Africa that lie south of the Sahara.

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Sulfadoxine

Sulfadoxine (also spelled sulphadoxine) is an ultra-long-lasting sulfonamide used in combination with pyrimethamine to treat malaria. Antimalarial medication and Sulfadoxine are antimalarial agents.

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Sulfadoxine/pyrimethamine

Sulfadoxine/pyrimethamine, sold under the brand name Fansidar, is a combination medication used to treat malaria. Antimalarial medication and Sulfadoxine/pyrimethamine are antimalarial agents.

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Sulfamethoxypyridazine

Sulfamethoxypyridazine is a sulfonamide antibacterial.

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Sulfonamide (medicine)

Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs.

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Synergy

Synergy is an interaction or cooperation giving rise to a whole that is greater than the simple sum of its parts (i.e., a non-linear addition of force, energy, or effect).

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Tafenoquine

Tafenoquine, sold under the brand name Krintafel among others, is a medication used to prevent and to treat malaria. Antimalarial medication and Tafenoquine are antimalarial agents.

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Teratology

Teratology is the study of abnormalities of physiological development in organisms during their life span.

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Tetracycline

Tetracycline, sold under various brand names, is an oral antibiotic in the tetracyclines family of medications, used to treat a number of infections, including acne, cholera, brucellosis, plague, malaria, and syphilis.

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Tinnitus

Tinnitus is a variety of sound that is heard when no corresponding external sound is present.

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Toxic encephalopathy

Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater cyanobacteria crusts.

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Trophozoite

A trophozoite (G. trope, nourishment + zoon, animal) is the activated, feeding stage in the life cycle of certain protozoa such as malaria-causing Plasmodium falciparum and those of the Giardia group.

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Tropical medicine

Tropical medicine is an interdisciplinary branch of medicine that deals with health issues that occur uniquely, are more widespread, or are more difficult to control in tropical and subtropical regions.

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United States

The United States of America (USA or U.S.A.), commonly known as the United States (US or U.S.) or America, is a country primarily located in North America.

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Vacuole

A vacuole is a membrane-bound organelle which is present in plant and fungal cells and some protist, animal, and bacterial cells.

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Vertigo

Vertigo is a condition in which a person has the sensation that they are moving, or that objects around them are moving, when they are not.

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Vestibulocochlear nerve

The vestibulocochlear nerve or auditory vestibular nerve, also known as the eighth cranial nerve, cranial nerve VIII, or simply CN VIII, is a cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain.

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Vietnam War

The Vietnam War was a conflict in Vietnam, Laos, and Cambodia from 1 November 1955 to the fall of Saigon on 30 April 1975.

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Walter Reed Army Institute of Research

The Walter Reed Army Institute of Research (WRAIR) is the largest biomedical research facility administered by the U.S. Department of Defense (DoD).

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Warburg's tincture

Warburg's tincture was a pharmaceutical drug, now obsolete. Antimalarial medication and Warburg's tincture are antimalarial agents.

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Western New Guinea

Western New Guinea, also known as Papua, Indonesian New Guinea, New Guinea, and Indonesian Papua, is the western half of the island of New Guinea, formerly Dutch and granted to Indonesia in 1962.

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World Health Organization

The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health.

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4-Aminobenzoic acid

4-Aminobenzoic acid (also known as para-aminobenzoic acid or PABA because the two functional groups are attached to the benzene ring across from one another in the para position) is an organic compound with the formula H2NC6H4CO2H.

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4-Aminoquinoline

4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline.

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References

[1] https://en.wikipedia.org/wiki/Antimalarial_medication

Also known as Anti malarial, Anti-malaria drug, Anti-malaria medication, Anti-malarial, Anti-malarial drug, Anti-malarial medication, Antimalaria, Antimalaria drug, Antimalaria medication, Antimalarial, Antimalarial agent, Antimalarial drug, Antimalarial drugs, Antimalarial medications, Antimalarials, Artemesinin-based combination, Artemisinin combination therapy, Artemisinin-based combination therapies, Artemisinin-based combination therapy, Artemisinin-combination therapy, Malaria drugs, Schizontocide.

, Dihydroartemisinin, Dihydrofolate reductase, Dihydropteroate synthase, Diospyros melanoxylon, Disease, Disease vector, DNA, DNA replication, Doxycycline, Drug of last resort, Drug resistance, Drug-induced hyperthermia, Endemic (epidemiology), Esophagitis, Ether, Evolution, Folate, Gamete, Gametocyte, Ge Hong, Glucose-6-phosphate dehydrogenase, Granulocyte, Half-life, Halofantrine, Heme, Hemolytic anemia, Hemozoin, Hydroxy group, Hydroxychloroquine, Hypoglycemia, Immunodeficiency, Indoor residual spraying, Infrastructure, Insect repellent, Insecticide, Insulin, Intermittent preventive therapy, Intramuscular injection, Intravenous therapy, Itch, Kidney failure, Lincomycin, Liver, Long QT syndrome, Lumefantrine, Lupus erythematosus, Maceration (cooking), Malaria, Malaria prophylaxis, Malaria vaccine, Martindale: The Complete Drug Reference, Medicines for Malaria Venture, Mefloquine, Merck Veterinary Manual, Metabolite, Methyl group, Mosquito net, Multiple drug resistance, Mutation, Myeloid tissue, Natural product, Neurotoxicity, Neutropenia, Nucleic acid, Ossification, Oxytetracycline, Papua New Guinea, Parasitemia, Peru, PH, Pharmacokinetics, Phenotypic plasticity, Photosensitivity, Piperaquine, Plasmodium, Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, Plasmodium vivax, Point mutation, Poultry, Pregnancy, Primaquine, Proguanil, Project 523, Prokaryotic small ribosomal subunit, Protein biosynthesis, Psoriasis, Psychosis, Public health, Purine, Pyrimethamine, Pyrimidine, Quinidine, Quinine, Respiratory system, Retinopathy, Rheumatoid arthritis, Ribosome, Route of administration, Side effect, Sinus arrhythmia, Stereoisomerism, Sub-Saharan Africa, Sulfadoxine, Sulfadoxine/pyrimethamine, Sulfamethoxypyridazine, Sulfonamide (medicine), Synergy, Tafenoquine, Teratology, Tetracycline, Tinnitus, Toxic encephalopathy, Trophozoite, Tropical medicine, United States, Vacuole, Vertigo, Vestibulocochlear nerve, Vietnam War, Walter Reed Army Institute of Research, Warburg's tincture, Western New Guinea, World Health Organization, 4-Aminobenzoic acid, 4-Aminoquinoline.