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Apricitabine, the Glossary

Index Apricitabine

Apricitabine (INN, codenamed AVX754 and SPD754, sometimes abbreviated to ATC) is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV.[1]

Table of Contents

  1. 33 relations: Adverse drug reaction, Australian Securities Exchange, Bone marrow suppression, Clinical trial, Cytidine, Diarrhea, Didanosine, Drug resistance, Emtricitabine, Fast track (FDA), Food and Drug Administration, Hepatotoxicity, HIV, Hypertriglyceridemia, International nonproprietary name, Kidney, Lamivudine, Lipase, Nasal congestion, National Institutes of Health, Nausea, Nephrotoxicity, Placebo, Randomized controlled trial, Reverse-transcriptase inhibitor, Shire (pharmaceutical company), Statistical significance, Structural analog, Tenofovir disoproxil, Thymidine, Upper respiratory tract infection, Viral load, Zidovudine.

  2. Experimental antiviral drugs
  3. Nucleoside analog reverse transcriptase inhibitors
  4. Oxathiolanes

Adverse drug reaction

An adverse drug reaction (ADR) is a harmful, unintended result caused by taking medication.

See Apricitabine and Adverse drug reaction

Australian Securities Exchange

Australian Securities Exchange Ltd (ASX) is an Australian public company that operates Australia's primary securities exchange, the Australian Securities Exchange (sometimes referred to outside of Australia as, or confused within Australia as, the Sydney Stock Exchange, a separate entity).

See Apricitabine and Australian Securities Exchange

Bone marrow suppression

Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).

See Apricitabine and Bone marrow suppression

Clinical trial

Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison.

See Apricitabine and Clinical trial

Cytidine

Cytidine (symbol C or Cyd) is a nucleoside molecule that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N1-glycosidic bond. Apricitabine and Cytidine are Hydroxymethyl compounds and Pyrimidones.

See Apricitabine and Cytidine

Diarrhea

Diarrhea (American English), also spelled diarrhoea or diarrhœa (British English), is the condition of having at least three loose, liquid, or watery bowel movements in a day.

See Apricitabine and Diarrhea

Didanosine

Didanosine (ddI, DDI), sold under the brand name Videx, is a medication used to treat HIV/AIDS. Apricitabine and Didanosine are Hydroxymethyl compounds and nucleoside analog reverse transcriptase inhibitors.

See Apricitabine and Didanosine

Drug resistance

Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition.

See Apricitabine and Drug resistance

Emtricitabine

Emtricitabine (commonly called FTC, systematic name 2',3'-dideoxy-5-fluoro-3'-thiacytidine), with trade name Emtriva (formerly Coviracil), is a nucleoside reverse-transcriptase inhibitor (NRTI) for the prevention and treatment of HIV infection in adults and children. Apricitabine and Emtricitabine are Hydroxymethyl compounds, nucleoside analog reverse transcriptase inhibitors, Oxathiolanes and Pyrimidones.

See Apricitabine and Emtricitabine

Fast track (FDA)

Fast track is a designation by the United States Food and Drug Administration (FDA) of an investigational drug for expedited review to facilitate development of drugs that treat a serious or life-threatening condition and fill an unmet medical need.

See Apricitabine and Fast track (FDA)

Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

See Apricitabine and Food and Drug Administration

Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.

See Apricitabine and Hepatotoxicity

HIV

The human immunodeficiency viruses (HIV) are two species of Lentivirus (a subgroup of retrovirus) that infect humans.

See Apricitabine and HIV

Hypertriglyceridemia

Hypertriglyceridemia is the presence of high amounts of triglycerides in the blood.

See Apricitabine and Hypertriglyceridemia

International nonproprietary name

An international nonproprietary name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or an active ingredient.

See Apricitabine and International nonproprietary name

Kidney

In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.

See Apricitabine and Kidney

Lamivudine

Lamivudine, commonly called 3TC, is an antiretroviral medication used to prevent and treat HIV/AIDS. Apricitabine and Lamivudine are Hydroxymethyl compounds, nucleoside analog reverse transcriptase inhibitors, Oxathiolanes and Pyrimidones.

See Apricitabine and Lamivudine

Lipase

In biochemistry, lipase refers to a class of enzymes that catalyzes the hydrolysis of fats.

See Apricitabine and Lipase

Nasal congestion

Nasal congestion is the partial or complete blockage of nasal passages, leading to impaired nasal breathing, usually due to membranes lining the nose becoming swollen from inflammation of blood vessels.

See Apricitabine and Nasal congestion

National Institutes of Health

The National Institutes of Health, commonly referred to as NIH, is the primary agency of the United States government responsible for biomedical and public health research.

See Apricitabine and National Institutes of Health

Nausea

Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit.

See Apricitabine and Nausea

Nephrotoxicity

Nephrotoxicity is toxicity in the kidneys.

See Apricitabine and Nephrotoxicity

Placebo

A placebo is a substance or treatment which is designed to have no therapeutic value.

See Apricitabine and Placebo

Randomized controlled trial

A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control.

See Apricitabine and Randomized controlled trial

Reverse-transcriptase inhibitor

Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication of HIV and other retroviruses.

See Apricitabine and Reverse-transcriptase inhibitor

Shire (pharmaceutical company)

Shire plc was a UK-founded Jersey-registered specialty biopharmaceutical company.

See Apricitabine and Shire (pharmaceutical company)

Statistical significance

In statistical hypothesis testing, a result has statistical significance when a result at least as "extreme" would be very infrequent if the null hypothesis were true.

See Apricitabine and Statistical significance

Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

See Apricitabine and Structural analog

Tenofovir disoproxil

Tenofovir disoproxil, sold under the brand name Viread among others, is a medication used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Apricitabine and Tenofovir disoproxil are nucleoside analog reverse transcriptase inhibitors.

See Apricitabine and Tenofovir disoproxil

Thymidine

Thymidine (symbol dT or dThd), also known as deoxythymidine, deoxyribosylthymine, or thymine deoxyriboside, is a pyrimidine deoxynucleoside. Apricitabine and Thymidine are Hydroxymethyl compounds.

See Apricitabine and Thymidine

Upper respiratory tract infection

An upper respiratory tract infection (URTI) is an illness caused by an acute infection, which involves the upper respiratory tract, including the nose, sinuses, pharynx, larynx or trachea.

See Apricitabine and Upper respiratory tract infection

Viral load

Viral load, also known as viral burden, is a numerical expression of the quantity of virus in a given volume of fluid, including biological and environmental specimens.

See Apricitabine and Viral load

Zidovudine

Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. Apricitabine and Zidovudine are Hydroxymethyl compounds and nucleoside analog reverse transcriptase inhibitors.

See Apricitabine and Zidovudine

See also

Experimental antiviral drugs

Nucleoside analog reverse transcriptase inhibitors

Oxathiolanes

References

[1] https://en.wikipedia.org/wiki/Apricitabine