Biphalin, the Glossary
Biphalin is a dimeric enkephalin endogenous peptide (Tyr-D-Ala-Gly-Phe-NH)2 composed of two tetrapeptides derived from enkephalins, connected 'tail-to-tail' by a hydrazide bridge.[1]
Table of Contents
16 relations: Alkaloid, Analgesic, Behavioral addiction, Dimerization (chemistry), Enkephalin, Etorphine, Hydrazide, Δ-opioid receptor, Lipophilicity, Molecular binding, Morphine, Nociception, Peritoneum, Phenylalanine, Structure–activity relationship, Tyrosine.
- Dimers (chemistry)
Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom.
Analgesic
An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management. Biphalin and analgesic are opioids.
Behavioral addiction
Behavioral addiction, process addiction, or non-substance-related disorder is a form of addiction that involves a compulsion to engage in a rewarding non-substance-related behavior – sometimes called a natural reward – despite any negative consequences to the person's physical, mental, social or financial well-being.
See Biphalin and Behavioral addiction
Dimerization (chemistry)
In chemistry, dimerization is the process of joining two identical or similar molecular entities by bonds. Biphalin and dimerization (chemistry) are dimers (chemistry).
See Biphalin and Dimerization (chemistry)
Enkephalin
An enkephalin is a pentapeptide involved in regulating nociception (pain sensation) in the body.
Etorphine
Etorphine (M99) is a semi-synthetic opioid possessing an analgesic potency approximately 1,000–3,000 times that of morphine.
Hydrazide
Hydrazides in organic chemistry are a class of organic compounds with the formula where R is acyl, sulfonyl, phosphoryl, phosphonyl and similar groups (chalcogen analogs are included, for example sulfur analogs called thiohydrazides), (subscription required) and R' are any groups (typically hydrogen or organyl).
Δ-opioid receptor
The δ-opioid receptor, also known as delta opioid receptor or simply delta receptor, abbreviated DOR or DOP, is an inhibitory 7-transmembrane G-protein coupled receptor coupled to the G protein Gi/G0 and has enkephalins as its endogenous ligands.
See Biphalin and Δ-opioid receptor
Lipophilicity
Lipophilicity (from Greek λίπος "fat" and φίλος "friendly") is the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene.
See Biphalin and Lipophilicity
Molecular binding
Molecular binding is an attractive interaction between two molecules that results in a stable association in which the molecules are in close proximity to each other.
See Biphalin and Molecular binding
Morphine
Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (Papaver somniferum).
Nociception
In physiology, nociception (/ˌnəʊsɪˈsɛpʃ(ə)n/), also nocioception) is the sensory nervous system's process of encoding noxious stimuli. It deals with a series of events and processes required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal to trigger an appropriate defensive response.
Peritoneum
The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids.
Phenylalanine
Phenylalanine (symbol Phe or F) is an essential α-amino acid with the formula.
See Biphalin and Phenylalanine
Structure–activity relationship
The structure–activity relationship (SAR) is the relationship between the chemical structure of a molecule and its biological activity.
See Biphalin and Structure–activity relationship
Tyrosine
-Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins.
See also
Dimers (chemistry)
- (Benzene)ruthenium dichloride dimer
- (Cymene)ruthenium dichloride dimer
- 1,1′-Bi-2-naphthol
- 5,6-Dihydro-5(α-thyminyl)thymine
- AP20187
- Allylpalladium chloride dimer
- Bicinchoninic acid
- Biphalin
- Bolazine
- Bolazine capronate
- Chiral oligoethylene glycol
- Chlorobis(cyclooctene)iridium dimer
- Chlorobis(cyclooctene)rhodium dimer
- Chlorobis(ethylene)rhodium dimer
- Cyclooctadiene rhodium chloride dimer
- Cyclopentadienylchromium tricarbonyl dimer
- Cyclopentadienyliron dicarbonyl dimer
- Cyclopentadienylmolybdenum tricarbonyl dimer
- Cyclopentadienyltungsten tricarbonyl dimer
- Diapocynin
- Dicoumarol
- Dicyclopentadiene
- Dimerization (chemistry)
- Dimerization of catharanthine and vindoline
- Dioxane tetraketone
- Diruthenium tetraacetate chloride
- Dithymoquinone
- FK1012
- Flupamesone
- Glycylglycine
- Gossypol
- Helium dimer
- Herrmann's catalyst
- Hibarimicinone
- Hydrodimerization
- Mebolazine
- Pentamethylcyclopentadienyl iridium dichloride dimer
- Pentamethylcyclopentadienyl rhodium dichloride dimer
- Pentamethylcyclopentadienyl ruthenium dichloride dimer
- Protein dimer
- Pyrimidine dimer
- Rhodium carbonyl chloride
- Rhodium(II) acetate
- Tris(dimethylamino)aluminium dimer
- Water dimer
References
[1] https://en.wikipedia.org/wiki/Biphalin
Also known as C46H56N10O10.