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Brimonidine, the Glossary

Brimonidine is an α2 agonist medication used to treat open-angle glaucoma, ocular hypertension, and rosacea.^[1]

24 relations: Adenylyl cyclase, Adrenergic agonist, Allergy, Alpha-2 adrenergic receptor, Aqueous humour, Brimonidine/timolol, Ciliary body, Clonidine, Cochrane (organisation), Cyclic adenosine monophosphate, Eye drop, Food and Drug Administration, G protein-coupled receptor, Generic drug, Glaucoma, Hypotension, Intraocular pressure, Liver, Medication, Ocular hypertension, Pregnancy, Rosacea, Timolol, Topical medication.
Alpha-2 adrenergic receptor agonists
Quinoxalines

Adenylyl cyclase

Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase (cyclizing; 3′,5′-cyclic-AMP-forming).

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Adrenergic agonist

An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors.

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Allergy

Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Aqueous humour

The aqueous humour is a transparent water-like fluid similar to blood plasma, but containing low protein concentrations.

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Brimonidine/timolol

Brimonidine/timolol, sold under the brand name Combigan among others, is a fixed-dose combination medication eye drop used for the treatment of glaucoma. Brimonidine and Brimonidine/timolol are drugs developed by AbbVie and Ophthalmology drugs.

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Ciliary body

The ciliary body is a part of the eye that includes the ciliary muscle, which controls the shape of the lens, and the ciliary epithelium, which produces the aqueous humor.

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Clonidine

Clonidine, sold under the brand name Catapres among others, is an α2A-adrenergic agonist medication used to treat high blood pressure, ADHD, drug withdrawal (alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions. Brimonidine and Clonidine are alpha-2 adrenergic receptor agonists, Imidazolines and Ophthalmology drugs.

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Cochrane (organisation)

Cochrane is a British international charitable organisation formed to synthesize medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers.

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Cyclic adenosine monophosphate

Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger, or cellular signal occurring within cells, that is important in many biological processes.

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Eye drop

Eye drops or eyedrops are liquid drops applied directly to the surface of the eye usually in small amounts such as a single drop or a few drops. Brimonidine and eye drop are Ophthalmology drugs.

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Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

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G protein-coupled receptor

G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses.

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Generic drug

A generic drug (or simply generic) is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents.

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Glaucoma

Glaucoma is a group of eye diseases that lead to damage of the optic nerve, which transmits visual information from the eye to the brain.

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Hypotension

Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure.

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Intraocular pressure

Intraocular pressure (IOP) is the fluid pressure inside the eye.

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Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

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Medication

A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Ocular hypertension

Ocular hypertension is the presence of elevated fluid pressure inside the eye (intraocular pressure), usually with no optic nerve damage or visual field loss.

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Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

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Rosacea

Rosacea is a long-term skin condition that typically affects the face.

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Timolol

Timolol is a beta blocker medication used either by mouth or as eye drops. Brimonidine and Timolol are Ophthalmology drugs.

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Topical medication

A topical medication is a medication that is applied to a particular place on or in the body.

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References

[1] https://en.wikipedia.org/wiki/Brimonidine

Also known as ATC code D11AX21, ATC code S01EA05, ATCvet code QD11AX21, ATCvet code QS01EA05, Alphagan, Alphagan P, Alphagan-P, Brimonidine Tartrate, Brimonidine ophthalmic, C11H10BrN5, Lumify, Mirvaso, Qoliana.