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Cell adhesion, the Glossary

Index Cell adhesion

Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface.[1]

Table of Contents

  1. 89 relations: Adherens junction, Arthritis, Autoantibody, Autoimmune disease, Bacteria, Bacterial adhesin, Basal lamina, Biochemical cascade, Cadherin, Catenin, CD4, Cell adhesion molecule, Cell junction, Cell migration, Cell signaling, Circumsporozoite protein, Claudin, Conformational change, Connexin, Connexon, Cytoskeleton, Desmocollin, Desmoglein, Desmosome, Differential adhesion hypothesis, Disease, Endothelium, Envelope glycoprotein GP120, Epithelium, Extracellular matrix, Fibronectin, Filamin, Flagellum, Focal adhesion, Fungal adhesin, Fungus, Gap junction, Genetics, Hemagglutinin, Hemidesmosome, Hepatitis C virus, HIV, Immune response, Immunoglobulin domain, Immunoglobulin superfamily, Infection, Inflammation, Influenza, Integrin, Intercellular adhesion molecule, ... Expand index (39 more) »

Adherens junction

In cell biology, adherens junctions (or zonula adherens, intermediate junction, or "belt desmosome") are protein complexes that occur at cell–cell junctions and cell–matrix junctions in epithelial and endothelial tissues, usually more basal than tight junctions.

See Cell adhesion and Adherens junction

Arthritis

Arthritis is a term often used to mean any disorder that affects joints.

See Cell adhesion and Arthritis

Autoantibody

An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins.

See Cell adhesion and Autoantibody

Autoimmune disease

An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms.

See Cell adhesion and Autoimmune disease

Bacteria

Bacteria (bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell.

See Cell adhesion and Bacteria

Bacterial adhesin

Adhesins are cell-surface components or appendages of bacteria that facilitate adhesion or adherence to other cells or to surfaces, usually in the host they are infecting or living in.

See Cell adhesion and Bacterial adhesin

Basal lamina

The basal lamina is a layer of extracellular matrix secreted by the epithelial cells, on which the epithelium sits.

See Cell adhesion and Basal lamina

Biochemical cascade

A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions that occur within a biological cell when initiated by a stimulus.

See Cell adhesion and Biochemical cascade

Cadherin

Cadherins (named for "calcium-dependent adhesion") are cell adhesion molecules important in forming adherens junctions that let cells adhere to each other.

See Cell adhesion and Cadherin

Catenin

Catenins are a family of proteins found in complexes with cadherin cell adhesion molecules of animal cells.

See Cell adhesion and Catenin

CD4

In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR).

See Cell adhesion and CD4

Cell adhesion molecule

Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion.

See Cell adhesion and Cell adhesion molecule

Cell junction

Cell junctions or junctional complexes are a class of cellular structures consisting of multiprotein complexes that provide contact or adhesion between neighboring cells or between a cell and the extracellular matrix in animals.

See Cell adhesion and Cell junction

Cell migration

Cell migration is a central process in the development and maintenance of multicellular organisms.

See Cell adhesion and Cell migration

Cell signaling

In biology, cell signaling (cell signalling in British English) is the process by which a cell interacts with itself, other cells, and the environment.

See Cell adhesion and Cell signaling

Circumsporozoite protein

Circumsporozoite protein (CSP) is a secreted protein of the sporozoite stage of the malaria parasite (Plasmodium sp.) and is the antigenic target of RTS,S and other malaria vaccines.

See Cell adhesion and Circumsporozoite protein

Claudin

Claudins are a family of proteins which, along with occludin, are the most important components of the tight junctions (zonulae occludentes).

See Cell adhesion and Claudin

Conformational change

In biochemistry, a conformational change is a change in the shape of a macromolecule, often induced by environmental factors.

See Cell adhesion and Conformational change

Connexin

Connexins (Cx), or gap junction proteins, are structurally related transmembrane proteins that assemble to form vertebrate gap junctions.

See Cell adhesion and Connexin

Connexon

In biology, a connexon, also known as a connexin hemichannel, is an assembly of six proteins called connexins that form the pore for a gap junction between the cytoplasm of two adjacent cells.

See Cell adhesion and Connexon

Cytoskeleton

The cytoskeleton is a complex, dynamic network of interlinking protein filaments present in the cytoplasm of all cells, including those of bacteria and archaea.

See Cell adhesion and Cytoskeleton

Desmocollin

Desmocollins are a subfamily of desmosomal cadherins, the transmembrane constituents of desmosomes.

See Cell adhesion and Desmocollin

Desmoglein

The desmogleins are a family of desmosomal cadherins consisting of proteins DSG1, DSG2, DSG3, and DSG4.

See Cell adhesion and Desmoglein

Desmosome

A desmosome ("binding body"), also known as a macula adherens (plural: maculae adherentes) (Latin for adhering spot), is a cell structure specialized for cell-to-cell adhesion.

See Cell adhesion and Desmosome

Differential adhesion hypothesis

Differential adhesion hypothesis (DAH) is a hypothesis that explains cellular movement during morphogenesis with thermodynamic principles.

See Cell adhesion and Differential adhesion hypothesis

Disease

A disease is a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to any external injury.

See Cell adhesion and Disease

Endothelium

The endothelium (endothelia) is a single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels.

See Cell adhesion and Endothelium

Envelope glycoprotein GP120

Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope.

See Cell adhesion and Envelope glycoprotein GP120

Epithelium

Epithelium or epithelial tissue is a thin, continuous, protective layer of compactly packed cells with little extracellular matrix.

See Cell adhesion and Epithelium

In biology, the extracellular matrix (ECM), also called intercellular matrix (ICM), is a network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide structural and biochemical support to surrounding cells.

See Cell adhesion and Extracellular matrix

Fibronectin

Fibronectin is a high-molecular weight (~500-~600 kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins.

See Cell adhesion and Fibronectin

Filamin

Filamins are a class of proteins that hold two actin filaments at large angles.

See Cell adhesion and Filamin

Flagellum

A flagellum (flagella) (Latin for 'whip' or 'scourge') is a hairlike appendage that protrudes from certain plant and animal sperm cells, from fungal spores (zoospores), and from a wide range of microorganisms to provide motility.

See Cell adhesion and Flagellum

Focal adhesion

In cell biology, focal adhesions (also cell–matrix adhesions or FAs) are large macromolecular assemblies through which mechanical force and regulatory signals are transmitted between the extracellular matrix (ECM) and an interacting cell.

See Cell adhesion and Focal adhesion

Fungal adhesin

Fungal adhesins are proteins located on the surface of fungal cells, specifically found on the outside of the cell wall.

See Cell adhesion and Fungal adhesin

Fungus

A fungus (fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

See Cell adhesion and Fungus

Gap junction

Gap junctions are membrane channels between cells that allow the exchange of substances from the cytoplasm of one cell directly to the cytoplasm of an adjacent cell.

See Cell adhesion and Gap junction

Genetics

Genetics is the study of genes, genetic variation, and heredity in organisms.

See Cell adhesion and Genetics

Hemagglutinin

In molecular biology, hemagglutinins (alternatively spelt haemagglutinin, from the Greek haima, 'blood' + Latin gluten, 'glue') are receptor-binding membrane fusion glycoproteins produced by viruses in the Paramyxoviridae and Orthomyxoviridae families.

See Cell adhesion and Hemagglutinin

Hemidesmosome

Hemidesmosomes are very small stud-like structures found in keratinocytes of the epidermis of skin that attach to the extracellular matrix.

See Cell adhesion and Hemidesmosome

Hepatitis C virus

The hepatitis C virus (HCV) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae.

See Cell adhesion and Hepatitis C virus

HIV

The human immunodeficiency viruses (HIV) are two species of Lentivirus (a subgroup of retrovirus) that infect humans.

See Cell adhesion and HIV

Immune response

An immune response is a physiological reaction which occurs within an organism in the context of inflammation for the purpose of defending against exogenous factors.

See Cell adhesion and Immune response

Immunoglobulin domain

The immunoglobulin domain, also known as the immunoglobulin fold, is a type of protein domain that consists of a 2-layer sandwich of 7-9 antiparallel β-strands arranged in two β-sheets with a Greek key topology, consisting of about 125 amino acids.

See Cell adhesion and Immunoglobulin domain

Immunoglobulin superfamily

The immunoglobulin superfamily (IgSF) is a large protein superfamily of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells.

See Cell adhesion and Immunoglobulin superfamily

Infection

An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce.

See Cell adhesion and Infection

Inflammation

Inflammation (from inflammatio) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.

See Cell adhesion and Inflammation

Influenza

Influenza, commonly known as "the flu" or just "flu", is an infectious disease caused by influenza viruses.

See Cell adhesion and Influenza

Integrin

Integrins are transmembrane receptors that help cell-cell and cell-extracellular matrix (ECM) adhesion.

See Cell adhesion and Integrin

Intercellular adhesion molecule

In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily.

See Cell adhesion and Intercellular adhesion molecule

Intermediate filaments (IFs) are cytoskeletal structural components found in the cells of vertebrates, and many invertebrates.

See Cell adhesion and Intermediate filament

Keratin

Keratin is one of a family of structural fibrous proteins also known as scleroproteins.

See Cell adhesion and Keratin

Laminin

Laminins are a family of glycoproteins of the extracellular matrix of all animals.

See Cell adhesion and Laminin

Leukocyte adhesion deficiency

Leukocyte adhesion deficiency (LAD) is a rare autosomal recessive disorder characterized by immunodeficiency resulting in recurrent infections.

See Cell adhesion and Leukocyte adhesion deficiency

Ligand

In coordination chemistry, a ligand is an ion or molecule with a functional group that binds to a central metal atom to form a coordination complex.

See Cell adhesion and Ligand

Lymphocyte

A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates.

See Cell adhesion and Lymphocyte

Malaria

Malaria is a mosquito-borne infectious disease that affects vertebrates.

See Cell adhesion and Malaria

Merozoite surface protein

Merozoite surface proteins are both integral and peripheral membrane proteins found on the surface of a merozoite, an early life cycle stage of a protozoan.

See Cell adhesion and Merozoite surface protein

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor.

See Cell adhesion and Metastasis

Microfilament

Microfilaments, also called actin filaments, are protein filaments in the cytoplasm of eukaryotic cells that form part of the cytoskeleton.

See Cell adhesion and Microfilament

Multicellular organism

A multicellular organism is an organism that consists of more than one cell, unlike unicellular organisms.

See Cell adhesion and Multicellular organism

Neural cell adhesion molecule

Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle.

See Cell adhesion and Neural cell adhesion molecule

Occludin

Occludin is a transmembrane protein that regulates the permeability of epithelial and endothelial barriers.

See Cell adhesion and Occludin

Paracellular transport

Paracellular transport refers to the transfer of substances across an epithelium by passing through the intercellular space between the cells.

See Cell adhesion and Paracellular transport

Pemphigus

Pemphigus is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes.

See Cell adhesion and Pemphigus

Pilus

A pilus (Latin for 'hair';: pili) is a hair-like appendage found on the surface of many bacteria and archaea.

See Cell adhesion and Pilus

Plasmodesma

Plasmodesmata (singular: plasmodesma) are microscopic channels which traverse the cell walls of plant cells and some algal cells, enabling transport and communication between them.

See Cell adhesion and Plasmodesma

Plasmodium falciparum

Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.

See Cell adhesion and Plasmodium falciparum

Plectin

Plectin is a giant protein found in nearly all mammalian cells which acts as a link between the three main components of the cytoskeleton: actin microfilaments, microtubules and intermediate filaments.

See Cell adhesion and Plectin

Polymerization

In polymer chemistry, polymerization (American English), or polymerisation (British English), is a process of reacting monomer molecules together in a chemical reaction to form polymer chains or three-dimensional networks.

See Cell adhesion and Polymerization

Prokaryote

A prokaryote (less commonly spelled procaryote) is a single-cell organism whose cell lacks a nucleus and other membrane-bound organelles.

See Cell adhesion and Prokaryote

Protein complex

A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.

See Cell adhesion and Protein complex

Protein dynamics

In molecular biology, proteins are generally thought to adopt unique structures determined by their amino acid sequences.

See Cell adhesion and Protein dynamics

Protozoa

Protozoa (protozoan or protozoon; alternative plural: protozoans) are a polyphyletic group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic debris.

See Cell adhesion and Protozoa

Red blood cell

Red blood cells (RBCs), referred to as erythrocytes (with -cyte translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen to the body tissues—via blood flow through the circulatory system.

See Cell adhesion and Red blood cell

Role of cell adhesions in neural development

Cellular adhesions can be defined as proteins or protein aggregates that form mechanical and chemical linkages between the intracellular and extracellular space.

See Cell adhesion and Role of cell adhesions in neural development

Scaffold protein

In biology, scaffold proteins are crucial regulators of many key signalling pathways.

See Cell adhesion and Scaffold protein

Selectin

The selectins (cluster of differentiation 62 or CD62) are a family of cell adhesion molecules (or CAMs).

See Cell adhesion and Selectin

Sialic acid

Sialic acids are a class of alpha-keto acid sugars with a nine-carbon backbone.

See Cell adhesion and Sialic acid

Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events.

See Cell adhesion and Signal transduction

Sugar

Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food.

See Cell adhesion and Sugar

Talin (protein)

Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell–substratum contact and, in lymphocytes, at cell–cell contacts.

See Cell adhesion and Talin (protein)

Tight junction

Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens), are multiprotein junctional complexes whose canonical function is to prevent leakage of solutes and water and seals between the epithelial cells.

See Cell adhesion and Tight junction

Tropism

In biology, a tropism is a phenomenon indicating the growth or turning movement of an organism, usually a plant, in response to an environmental stimulus.

See Cell adhesion and Tropism

VCAM-1

Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the VCAM1 gene.

See Cell adhesion and VCAM-1

Vinculin

In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton.

See Cell adhesion and Vinculin

Virus

A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism.

See Cell adhesion and Virus

Voltage-gated ion channel

Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.

See Cell adhesion and Voltage-gated ion channel

White blood cell

White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

See Cell adhesion and White blood cell

References

[1] https://en.wikipedia.org/wiki/Cell_adhesion

Also known as Cell-cell adhesion, Cellular adhesion, Tumor adhesion.

, Intermediate filament, Keratin, Laminin, Leukocyte adhesion deficiency, Ligand, Lymphocyte, Malaria, Merozoite surface protein, Metastasis, Microfilament, Multicellular organism, Neural cell adhesion molecule, Occludin, Paracellular transport, Pemphigus, Pilus, Plasmodesma, Plasmodium falciparum, Plectin, Polymerization, Prokaryote, Protein complex, Protein dynamics, Protozoa, Red blood cell, Role of cell adhesions in neural development, Scaffold protein, Selectin, Sialic acid, Signal transduction, Sugar, Talin (protein), Tight junction, Tropism, VCAM-1, Vinculin, Virus, Voltage-gated ion channel, White blood cell.