Congenital insensitivity to pain, the Glossary

Table of Contents

1. 35 relations: ABC-Clio, Action potential, Autism, Chili pepper, Cognition, Congenital insensitivity to pain with anhidrosis, Cornea, Deletion (genetics), Dorsal root ganglion, Elsevier, Endorphins, Familial dysautonomia, Fatty-acid amide hydrolase 1, Hereditary sensory and autonomic neuropathy, Human brain, Hypoalgesia, Infection, Kiruna Municipality, Mouth, Naloxone, Naltrexone, Opioid antagonist, Pain, Pain asymbolia, PRDM12, Pseudogene, Sense, Signs and symptoms, Sodium voltage-gated channel alpha subunit 9, Springer Science+Business Media, Sweden, Tongue, Vittangi, Voltage-gated sodium channel, Zinc finger homeobox 2.

ABC-Clio

ABC-Clio, LLC (stylized ABC-CLIO) is an American publishing company for academic reference works and periodicals primarily on topics such as history and social sciences for educational and public library settings.

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Action potential

An action potential occurs when the membrane potential of a specific cell rapidly rises and falls.

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Autism

Autism, also called autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental disorder characterised by symptoms of deficient reciprocal social communication and the presence of restricted, repetitive and inflexible patterns of behavior that are impairing in multiple contexts and excessive or atypical to be developmentally and socioculturally inappropriate.

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Chili pepper

Chili peppers, also spelled chile or chilli, are varieties of the berry-fruit of plants from the genus Capsicum, which are members of the nightshade family Solanaceae, cultivated for their pungency.

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Cognition

Cognition is the "mental action or process of acquiring knowledge and understanding through thought, experience, and the senses".

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Congenital insensitivity to pain with anhidrosis

Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder of the nervous system which prevents the feeling of pain or temperature and prevents a person from sweating. Congenital insensitivity to pain and Congenital insensitivity to pain with anhidrosis are rare diseases.

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Cornea

The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber.

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Deletion (genetics)

In genetics, a deletion (also called gene deletion, deficiency, or deletion mutation) (sign: Δ) is a mutation (a genetic aberration) in which a part of a chromosome or a sequence of DNA is left out during DNA replication.

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Dorsal root ganglion

A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve.

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Elsevier

Elsevier is a Dutch academic publishing company specializing in scientific, technical, and medical content.

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Endorphins

Endorphins (contracted from endogenous morphine) are peptides produced in the brain that block the perception of pain and increase feelings of wellbeing. Congenital insensitivity to pain and Endorphins are pain.

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Familial dysautonomia

Familial dysautonomia (FD), also known as Riley-Day syndrome, is a rare, progressive, recessive genetic disorder of the autonomic nervous system that affects the development and survival of sensory, sympathetic, and some parasympathetic neurons in the autonomic and sensory nervous system. Congenital insensitivity to pain and Familial dysautonomia are rare diseases and syndromes.

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Fatty-acid amide hydrolase 1

Fatty-acid amide hydrolase 1 (FAAH) is a member of the serine hydrolase family of enzymes.

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Hereditary sensory and autonomic neuropathy

Hereditary sensory and autonomic neuropathy (HSAN) or hereditary sensory neuropathy (HSN) is a condition used to describe any of the types of this disease which inhibit sensation. Congenital insensitivity to pain and hereditary sensory and autonomic neuropathy are rare diseases.

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Human brain

The brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system.

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Hypoalgesia

Hypoalgesia or hypalgesia denotes a decreased sensitivity to painful stimuli.

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Infection

An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce.

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Kiruna Municipality

Kiruna Municipality (Kiruna kommun; Giron gielda; Meänkieli: Kierunan kunta; Finnish: Kiirunan kunta) is a municipality in Norrbotten County in northernmost Sweden.

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Mouth

The mouth is the body orifice through which many animals ingest food and vocalize.

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Naloxone

Naloxone is an opioid antagonist: a medication used to reverse or reduce the effects of opioids.

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Naltrexone

Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol use or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. It has also been found effective in the treatment of other addictions and may be used for them off-label.

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Opioid antagonist

An opioid antagonist, or opioid receptor antagonist, is a receptor antagonist that acts on one or more of the opioid receptors.

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Pain

Pain is a distressing feeling often caused by intense or damaging stimuli.

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Pain asymbolia

Pain asymbolia, also called pain dissociation, is a condition in which pain is experienced without unpleasantness. Congenital insensitivity to pain and pain asymbolia are pain.

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PRDM12

PR domain zinc finger protein 12 is a protein that in humans is encoded by the PRDM12 gene.

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Pseudogene

Pseudogenes are nonfunctional segments of DNA that resemble functional genes.

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Sense

A sense is a biological system used by an organism for sensation, the process of gathering information about the surroundings through the detection of stimuli.

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Signs and symptoms

Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition.

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Sodium voltage-gated channel alpha subunit 9

Sodium voltage-gated channel alpha subunit 9 (also Nav1.7) is a sodium ion channel that in humans is encoded by the SCN9A gene.

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Springer Science+Business Media, commonly known as Springer, is a German multinational publishing company of books, e-books and peer-reviewed journals in science, humanities, technical and medical (STM) publishing.

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Sweden

Sweden, formally the Kingdom of Sweden, is a Nordic country located on the Scandinavian Peninsula in Northern Europe.

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Tongue

The tongue is a muscular organ in the mouth of a typical tetrapod.

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Vittangi

Vittangi is a locality situated in Kiruna Municipality, Norrbotten County, Sweden with 784 inhabitants in 2010.

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Voltage-gated sodium channel

Voltage-gated sodium channels (VGSCs), also known as voltage-dependent sodium channels (VDSCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the sodium ion Na+.

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Zinc finger homeobox 2

Zinc finger homeobox 2 is a protein that in humans is encoded by the ZFHX2 gene.

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References

[1] https://en.wikipedia.org/wiki/Congenital_insensitivity_to_pain

Also known as Channelopathy-associated insensitivity to pain, Congenital absence of pain, Congenital analgesia, Congenital analgia, Congenital indifference to pain, Congenital pain insensitivity, Pain agnosia, Pain insensitivity, congenital.