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Cytarabine, the Glossary

Index Cytarabine

Cytarabine, also known as cytosine arabinoside (ara-C), is a chemotherapy medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and non-Hodgkin's lymphoma.[1]

Table of Contents

  1. 60 relations: Acute lymphoblastic leukemia, Acute myeloid leukemia, Allergy, Anemia, Antimetabolite, Antiviral drug, Arabinofuranosylcytosine triphosphate, Arabinose, Ataxia, Bleeding, Bone marrow suppression, Cell cycle, Cerebellum, Chemotherapy, Chemotherapy-induced acral erythema, Chronic myelogenous leukemia, Conjunctivitis, Cytosine, Dermatitis, DNA, DNA polymerase, Fever, Food and Drug Administration, Glia, Granulocyte, Herpesviridae, Induction chemotherapy, Intrathecal administration, Intravenous therapy, Kidney, Leukopenia, Liposome, Liver, Liver disease, Lymphoma, Mitosis, Myelopathy, Nervous system, Neuron, Non-Hodgkin lymphoma, Non-homologous end joining, Nucleoside, Nucleoside analogue, Nucleotide, Pancreatitis, Peripheral neuropathy, Pneumonitis, Pregnancy, RNA polymerase, S phase, ... Expand index (10 more) »

  2. Arabinosides
  3. DNA polymerase inhibitors
  4. DNA replication inhibitors
  5. Pyrimidine antagonists
  6. RNA polymerase inhibitors

Acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes.

See Cytarabine and Acute lymphoblastic leukemia

Acute myeloid leukemia

Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production.

See Cytarabine and Acute myeloid leukemia

Allergy

Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.

See Cytarabine and Allergy

Anemia

Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen.

See Cytarabine and Anemia

An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.

See Cytarabine and Antimetabolite

Antiviral drug

Antiviral drugs are a class of medication used for treating viral infections. Cytarabine and Antiviral drug are Antiviral drugs.

See Cytarabine and Antiviral drug

Arabinofuranosylcytosine triphosphate

Arabinofuranosylcytosine triphosphate is a nucleotide that inhibits the synthesis of DNA by acting as an antimetabolic agent against deoxycytidine (a component of DNA). Cytarabine and Arabinofuranosylcytosine triphosphate are Arabinosides and Pyrimidones.

See Cytarabine and Arabinofuranosylcytosine triphosphate

Arabinose

Arabinose is an aldopentose – a monosaccharide containing five carbon atoms, and including an aldehyde (CHO) functional group.

See Cytarabine and Arabinose

Ataxia

Ataxia (from Greek α- + -τάξις.

See Cytarabine and Ataxia

Bleeding

Bleeding, hemorrhage, haemorrhage or blood loss is blood escaping from the circulatory system from damaged blood vessels.

See Cytarabine and Bleeding

Bone marrow suppression

Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).

See Cytarabine and Bone marrow suppression

Cell cycle

The cell cycle, or cell-division cycle, is the sequential series of events that take place in a cell that causes it to divide into two daughter cells.

See Cytarabine and Cell cycle

Cerebellum

The cerebellum (cerebella or cerebellums; Latin for "little brain") is a major feature of the hindbrain of all vertebrates.

See Cytarabine and Cerebellum

Chemotherapy

Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) in a standard regimen. Cytarabine and Chemotherapy are cancer treatments.

See Cytarabine and Chemotherapy

Chemotherapy-induced acral erythema

Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.

See Cytarabine and Chemotherapy-induced acral erythema

Chronic myelogenous leukemia

Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells.

See Cytarabine and Chronic myelogenous leukemia

Conjunctivitis

Conjunctivitis, also known as pink eye, is inflammation of the outermost layer of the white part of the eye and the inner surface of the eyelid.

See Cytarabine and Conjunctivitis

Cytosine

Cytosine (symbol C or Cyt) is one of the four nucleobases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). Cytarabine and Cytosine are Pyrimidones.

See Cytarabine and Cytosine

Dermatitis

Dermatitis is inflammation of the skin, typically characterized by itchiness, redness and a rash.

See Cytarabine and Dermatitis

DNA

Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.

See Cytarabine and DNA

DNA polymerase

A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA.

See Cytarabine and DNA polymerase

Fever

Fever or pyrexia in humans is a body temperature above the normal range due to an increase in the body's temperature set point in the hypothalamus.

See Cytarabine and Fever

Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

See Cytarabine and Food and Drug Administration

Glia

Glia, also called glial cells (gliocytes) or neuroglia, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system that do not produce electrical impulses.

See Cytarabine and Glia

Granulocyte

Granulocytes are cells in the innate immune system characterized by the presence of specific granules in their cytoplasm.

See Cytarabine and Granulocyte

Herpesviridae

Herpesviridae is a large family of DNA viruses that cause infections and certain diseases in animals, including humans.

See Cytarabine and Herpesviridae

Induction chemotherapy

Induction chemotherapy is the first-line treatment of cancer with a chemotherapeutic drug.

See Cytarabine and Induction chemotherapy

Intrathecal administration

Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF).

See Cytarabine and Intrathecal administration

Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

See Cytarabine and Intravenous therapy

Kidney

In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.

See Cytarabine and Kidney

Leukopenia

Leukopenia is a decrease in the number of leukocytes (WBC).

See Cytarabine and Leukopenia

Liposome

A liposome is a small artificial vesicle, spherical in shape, having at least one lipid bilayer.

See Cytarabine and Liposome

Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

See Cytarabine and Liver

Liver disease

Liver disease, or hepatic disease, is any of many diseases of the liver.

See Cytarabine and Liver disease

Lymphoma

Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell).

See Cytarabine and Lymphoma

Mitosis

Mitosis is a part of the cell cycle in which replicated chromosomes are separated into two new nuclei.

See Cytarabine and Mitosis

Myelopathy

Myelopathy describes any neurologic deficit related to the spinal cord.

See Cytarabine and Myelopathy

Nervous system

In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body.

See Cytarabine and Nervous system

Neuron

A neuron, neurone, or nerve cell is an excitable cell that fires electric signals called action potentials across a neural network in the nervous system.

See Cytarabine and Neuron

Non-Hodgkin lymphoma

Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas.

See Cytarabine and Non-Hodgkin lymphoma

Non-homologous end joining

Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA.

See Cytarabine and Non-homologous end joining

Nucleoside

Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. Cytarabine and Nucleoside are nucleosides.

See Cytarabine and Nucleoside

Nucleoside analogue

Nucleoside analogues are structural analogues of a nucleoside, which normally contain a nucleobase and a sugar. Cytarabine and nucleoside analogue are Antiviral drugs and nucleosides.

See Cytarabine and Nucleoside analogue

Nucleotide

Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate.

See Cytarabine and Nucleotide

Pancreatitis

Pancreatitis is a condition characterized by inflammation of the pancreas.

See Cytarabine and Pancreatitis

Peripheral neuropathy

Peripheral neuropathy, often shortened to neuropathy, refers to damage or disease affecting the nerves.

See Cytarabine and Peripheral neuropathy

Pneumonitis

Pneumonitis describes general inflammation of lung tissue.

See Cytarabine and Pneumonitis

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Cytarabine and Pregnancy

RNA polymerase

In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that catalyzes the chemical reactions that synthesize RNA from a DNA template.

See Cytarabine and RNA polymerase

S phase

S phase (Synthesis phase) is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase.

See Cytarabine and S phase

SAMHD1

SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene.

See Cytarabine and SAMHD1

Sponge

Sponges (also known as sea sponges), the members of the phylum Porifera (meaning 'pore bearer'), are a basal animal clade as a sister of the diploblasts.

See Cytarabine and Sponge

Stomatitis

Stomatitis is inflammation of the mouth and lips.

See Cytarabine and Stomatitis

Subcutaneous administration

Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion.

See Cytarabine and Subcutaneous administration

Tectitethya crypta

Tectitethya crypta is a species of demosponge belonging to the family Tethyidae.

See Cytarabine and Tectitethya crypta

Thrombocytopenia

In hematology, thrombocytopenia is a condition characterized by abnormally low levels of platelets (also known as thrombocytes) in the blood.

See Cytarabine and Thrombocytopenia

Unconsciousness

Unconsciousness is a state in which a living individual exhibits a complete, or near-complete, inability to maintain an awareness of self and environment or to respond to any human or environmental stimulus.

See Cytarabine and Unconsciousness

University of California, Berkeley

The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California.

See Cytarabine and University of California, Berkeley

Upjohn

The Upjohn Company was an American pharmaceutical manufacturing firm founded in 1886 in Hastings, Michigan, by Dr.

See Cytarabine and Upjohn

WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. Cytarabine and WHO Model List of Essential Medicines are World Health Organization essential medicines.

See Cytarabine and WHO Model List of Essential Medicines

See also

Arabinosides

DNA polymerase inhibitors

DNA replication inhibitors

Pyrimidine antagonists

RNA polymerase inhibitors

References

[1] https://en.wikipedia.org/wiki/Cytarabine

Also known as 1-beta-D-arabinofuranosylcytosine, AR3, ATC code L01BC01, ATCvet code QL01BC01, Alexan, Ara C, Ara-C, Arabinofuranosylcytosine, Arabitin, Arafcyt, Cytarbel, Cytosar, Cytosar-U, Cytosine arabinoside, Depocyt, Depocyte, Erpalfa, Iretin, Spongocytidine, Tarabine, Udicil.

, SAMHD1, Sponge, Stomatitis, Subcutaneous administration, Tectitethya crypta, Thrombocytopenia, Unconsciousness, University of California, Berkeley, Upjohn, WHO Model List of Essential Medicines.