Dolichol, the Glossary
Dolichol refers to any of a group of long-chain mostly unsaturated organic compounds that are made up of varying numbers of isoprene units terminating in an α-saturated isoprenoid group, containing an alcohol functional group.[1]
Table of Contents
36 relations: Alcohol (chemistry), Alzheimer's disease, Antioxidant, Asparagine, Biomarkers of aging, Birkbeck, University of London, Cholesterol, Coenzyme Q10, Dehydrodolichyl diphosphate synthase, Dolichol kinase, Dolichol monophosphate, Endoplasmic reticulum, Farnesyl pyrophosphate, Glucose, Glycoprotein, Glycosylation, Human brain, Isoprene, Lipid peroxidation, Mannose, Mevalonate pathway, Mevalonic acid, N-Acetylglucosamine, N-linked glycosylation, Neurodegenerative disease, Neuromelanin, Oligosaccharide, Organic compound, Oxidative stress, Polyprenol, Post-translational modification, Progeroid syndromes, Protein, Saturated and unsaturated compounds, Statin, Terpenoid.
Alcohol (chemistry)
In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group bound to carbon.
See Dolichol and Alcohol (chemistry)
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.
See Dolichol and Alzheimer's disease
Antioxidant
Antioxidants are compounds that inhibit oxidation (usually occurring as autoxidation), a chemical reaction that can produce free radicals.
Asparagine
Asparagine (symbol Asn or N) is an α-amino acid that is used in the biosynthesis of proteins.
Biomarkers of aging
Biomarkers of aging are biomarkers that could predict functional capacity at some later age better than chronological age.
See Dolichol and Biomarkers of aging
Birkbeck, University of London
Birkbeck, University of London (formally Birkbeck College, University of London), is a research university located in London, England, and a member institution of the University of London.
See Dolichol and Birkbeck, University of London
Cholesterol
Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Coenzyme Q10
Coenzyme Q10 (CoQ10) also known as ubiquinone, is a naturally occurring biochemical cofactor (coenzyme) and an antioxidant produced by the human body.
Dehydrodolichyl diphosphate synthase
Dehydrodolichyl diphosphate synthase is an enzyme that in humans is encoded by the DHDDS gene.
See Dolichol and Dehydrodolichyl diphosphate synthase
Dolichol kinase
In enzymology, a dolichol kinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are CTP and dolichol, whereas its two products are CDP and dolichyl phosphate.
See Dolichol and Dolichol kinase
Dolichol monophosphate
Dolichol monophosphate is a phosphate ester of dolichol.
See Dolichol and Dolichol monophosphate
Endoplasmic reticulum
The endoplasmic reticulum (ER) is a part of a transportation system of the eukaryotic cell, and has many other important functions such as protein folding.
See Dolichol and Endoplasmic reticulum
Farnesyl pyrophosphate
Farnesyl pyrophosphate (FPP), also known as farnesyl diphosphate (FDP), is an intermediate in the biosynthesis of terpenes and terpenoids such as sterols and carotenoids.
See Dolichol and Farnesyl pyrophosphate
Glucose
Glucose is a sugar with the molecular formula.
Glycoprotein
Glycoproteins are proteins which contain oligosaccharide (sugar) chains covalently attached to amino acid side-chains.
Glycosylation
Glycosylation is the reaction in which a carbohydrate (or 'glycan'), i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor) in order to form a glycoconjugate.
See Dolichol and Glycosylation
Human brain
The brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system.
Isoprene
Isoprene, or 2-methyl-1,3-butadiene, is a common volatile organic compound with the formula CH2.
Lipid peroxidation
Lipid peroxidation, or lipid oxidation, is a complex chemical process that leads to oxidative degradation of lipids, resulting in the formation of peroxide and hydroperoxide derivatives.
See Dolichol and Lipid peroxidation
Mannose
Mannose is a sugar monomer of the aldohexose series of carbohydrates.
Mevalonate pathway
The mevalonate pathway, also known as the isoprenoid pathway or HMG-CoA reductase pathway is an essential metabolic pathway present in eukaryotes, archaea, and some bacteria.
See Dolichol and Mevalonate pathway
Mevalonic acid
Mevalonic acid (MVA) is a key organic compound in biochemistry; the name is a contraction of dihydroxymethylvalerolactone. Dolichol and Mevalonic acid are Primary alcohols.
See Dolichol and Mevalonic acid
N-Acetylglucosamine
N-Acetylglucosamine (GlcNAc) is an amide derivative of the monosaccharide glucose.
See Dolichol and N-Acetylglucosamine
N-linked glycosylation
N-linked glycosylation is the attachment of an oligosaccharide, a carbohydrate consisting of several sugar molecules, sometimes also referred to as glycan, to a nitrogen atom (the amide nitrogen of an asparagine (Asn) residue of a protein), in a process called N-glycosylation, studied in biochemistry.
See Dolichol and N-linked glycosylation
Neurodegenerative disease
A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration.
See Dolichol and Neurodegenerative disease
Neuromelanin
Neuromelanin (NM) is a dark pigment found in the brain which is structurally related to melanin.
Oligosaccharide
An oligosaccharide is a saccharide polymer containing a small number (typically three to ten) of monosaccharides (simple sugars).
See Dolichol and Oligosaccharide
Organic compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon.
See Dolichol and Organic compound
Oxidative stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Dolichol and Oxidative stress are cell biology.
See Dolichol and Oxidative stress
Polyprenol
Polyprenols are natural long-chain isoprenoid alcohols of the general formula H-(C5H8)n-OH, where n is the number of isoprene units. Dolichol and Polyprenol are Alkene derivatives and terpenes and terpenoids.
Post-translational modification
In molecular biology, post-translational modification (PTM) is the covalent process of changing proteins following protein biosynthesis. Dolichol and post-translational modification are cell biology.
See Dolichol and Post-translational modification
Progeroid syndromes
Progeroid syndromes (PS) are a group of rare genetic disorders that mimic physiological aging, making affected individuals appear to be older than they are.
See Dolichol and Progeroid syndromes
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.
Saturated and unsaturated compounds
A saturated compound is a chemical compound (or ion) that resists addition reactions, such as hydrogenation, oxidative addition, and binding of a Lewis base.
See Dolichol and Saturated and unsaturated compounds
Statin
Statins (or HMG-CoA reductase inhibitors) are a class of medications that reduce illness and mortality in people who are at high risk of cardiovascular disease.
Terpenoid
The terpenoids, also known as isoprenoids, are a class of naturally occurring organic chemicals derived from the 5-carbon compound isoprene and its derivatives called terpenes, diterpenes, etc. Dolichol and terpenoid are terpenes and terpenoids.
References
[1] https://en.wikipedia.org/wiki/Dolichol
Also known as C100H164O, Dolichols.