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EC586, the Glossary

EC586, also known as testosterone 17β-(1-((5-(aminosulfonyl)-2-pyridinyl)carbonyl)--proline), is an androgen and anabolic steroid which is under development by Evestra for use in androgen replacement therapy in men.^[1]

23 relations: Anabolic steroid, Androgen, Androgen ester, Androgen replacement therapy, Area under the curve (pharmacokinetics), Bioidentical hormone replacement therapy, EC508, Ester, First pass effect, Investigational New Drug, List of estrogen esters, Liver, Natural product, Oral administration, Pharmacokinetics, Potency (pharmacology), Prodrug, Proline, Propionic acid, Route of administration, Testosterone (medication), Testosterone propionate, Testosterone undecanoate.
Experimental sex-hormone agents
Sulfamates
Testosterone

Anabolic steroid

Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are a class of drugs that are structurally related to testosterone, the main male sex hormone, and produce effects by binding to the androgen receptor (AR). EC586 and anabolic steroid are Anabolic–androgenic steroids.

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Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. EC586 and androgen are Anabolic–androgenic steroids.

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Androgen ester

An androgen or anabolic steroid ester is an ester of an androgen/anabolic steroid (AAS) such as the natural testosterone or dihydrotestosterone (DHT) or the synthetic nandrolone (19-nortestosterone). EC586 and androgen ester are Anabolic–androgenic steroids, androgen esters and Androstanes.

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Androgen replacement therapy

Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced. EC586 and androgen replacement therapy are testosterone.

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Area under the curve (pharmacokinetics)

In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral of the concentration of a drug in blood plasma as a function of time (this can be done using liquid chromatography–mass spectrometry).

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Bioidentical hormone replacement therapy

Bioidentical hormone replacement therapy (BHRT), also known as bioidentical hormone therapy (BHT) or natural hormone therapy, is the use of hormones that are identical on a molecular level with endogenous hormones in hormone replacement therapy.

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EC508

EC508, also known as estradiol 17β-(1-(4-(aminosulfonyl)benzoyl)--proline), is an estrogen which is under development by Evestra for use in menopausal hormone therapy and as a hormonal contraceptive for the prevention of pregnancy in women. EC586 and EC508 are amino acids and experimental sex-hormone agents.

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Ester

In chemistry, an ester is a functional group derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group of that acid is replaced by an organyl group.

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First pass effect

The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

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Investigational New Drug

The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical company obtains permission to start human clinical trials and to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved.

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List of estrogen esters

This is a list of estrogen esters, or ester prodrugs of estrogens.

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Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

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Natural product

A natural product is a natural compound or substance produced by a living organism—that is, found in nature.

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Oral administration

| name.

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration.

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Potency (pharmacology)

In pharmacology, potency or biological potency is a measure of a drug's biological activity expressed in terms of the dose required to produce a pharmacological effect of given intensity.

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Prodrug

A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

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Proline

Proline (symbol Pro or P) is an organic acid classed as a proteinogenic amino acid (used in the biosynthesis of proteins), although it does not contain the amino group but is rather a secondary amine.

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Propionic acid

Propionic acid (from the Greek words πρῶτος: prōtos, meaning "first", and πίων: píōn, meaning "fat"; also known as propanoic acid) is a naturally occurring carboxylic acid with chemical formula.

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Route of administration

In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body.

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Testosterone (medication)

Testosterone (T) is a medication and naturally occurring steroid hormone. EC586 and Testosterone (medication) are Anabolic–androgenic steroids, Androstanes, Enones and testosterone.

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Testosterone propionate

Testosterone propionate, sold under the brand name Testoviron among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men. EC586 and testosterone propionate are Anabolic–androgenic steroids and Androstanes.

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Testosterone undecanoate

Testosterone undecanoate, sold under the brand name Nebido among others, is an androgen and anabolic steroid (AAS) medication that is used mainly in the treatment of low testosterone levels in men, It is taken by mouth or given by injection into muscle. EC586 and testosterone undecanoate are Anabolic–androgenic steroids and Androstanes.

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References

[1] https://en.wikipedia.org/wiki/EC586

Also known as 3-Oxoandrost-4-en-17β-yl 1-((5-(aminosulfonyl)-2-pyridinyl)carbonyl)-L-proline, 3-hydroxyestra-1,3,5(10)-trien-17β-yl 1-(4-(aminosulfonyl)benzoyl)-L-proline, Androst-4-en-17β-ol-3-one 17β-(1-((5-(aminosulfonyl)-2-pyridinyl)carbonyl)-L-proline), EC 586, EC-586, Testosterone 17β-(1-((5-(aminosulfonyl)-2-pyridinyl)carbonyl)-L-proline), Testosterone 17β-Aminosulfonylpyridinylcarbonylproline, Testosterone Aminosulfonylpyridinylcarbonylproline.